DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mob2 and Mob2

DIOPT Version :9

Sequence 1:	NP_729715.2	Gene:	Mob2 / 39293	FlyBaseID:	FBgn0259481	Length:	728	Species:	Drosophila melanogaster
Sequence 2:	NP_001361564.1	Gene:	Mob2 / 101513	MGIID:	1919891	Length:	266	Species:	Mus musculus

Alignment Length:	229	Identity:	102/229 - (44%)
Similarity:	137/229 - (59%)	Gaps:	3/229 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   297 LVAKARRKERDGDQNSTDTKLYLEESVLERKLPEADLKALVDLPAGLDYNEWLASHTLALFEHVN 361
            ::.|::.|.......:.:.|:|||....:.::.:.:.|.||.||..:|.||||||:|...|.|:|
Mouse    35 VLRKSKAKPNGKKPAAEEKKVYLEPEHTKSRITDFEFKELVVLPREIDLNEWLASNTTTFFHHIN 99

  Fly   362 LVYGTISEFCTQSGCADMTGPGNRTYLWFDEKGKKTRVAAPQYIDYVMTFTQKTVSDESIFPTKY 426
            |.|.|||||||...|..| ...|..|.|:||:|||.:..||||:|:||:..||.|:||.:|||||
Mouse   100 LQYSTISEFCTGETCQTM-AVCNTQYYWYDERGKKVKCTAPQYVDFVMSSVQKLVTDEDVFPTKY 163

  Fly   427 ANEFPGSFESIARKILRLQFHVIAHLYAAHFREIALLGLHTHLNLTFAHLTALHRRFNLIDEKET 491
            ..|||.||||:.:||.:..|||:.|:|.|||:|...|.||.|||..:.|.....|.|||:|.|||
Mouse   164 GREFPSSFESLVKKICKYLFHVLGHIYWAHFKETLALELHGHLNTLYVHFILFAREFNLLDPKET 228

  Fly   492 DVLRDL-EVALRLTDDTGGCQD-ATSTTSSVHDH 523
            .|:.|| ||......::|...| |.|..|...:|
Mouse   229 AVMDDLTEVLCSSPGNSGATGDGANSGASGAQNH 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mob2	NP_729715.2	Mob1_phocein	328..494	CDD:281617	85/165 (52%)
Mob2	NP_001361564.1	Mob1_phocein	63..231	CDD:397617	85/167 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	184	1.000	Domainoid score	I3414
eggNOG	1	0.900	-	-		E1_KOG0440
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1127941at2759
OrthoFinder	1	1.000	-	-		FOG0005522
OrthoInspector	1	1.000	-	-		oto93119
orthoMCL	1	0.900	-	-		OOG6_107229
Panther	1	1.100	-	-	LDO	PTHR22599
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4664
SonicParanoid	1	1.000	-	-		X3943
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.850