DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vha16-2 and vha-3

DIOPT Version :9

Sequence 1:	NP_729707.1	Gene:	Vha16-2 / 39282	FlyBaseID:	FBgn0028668	Length:	158	Species:	Drosophila melanogaster
Sequence 2:	NP_001367642.1	Gene:	vha-3 / 177018	WormBaseID:	WBGene00006912	Length:	161	Species:	Caenorhabditis elegans

Alignment Length:	152	Identity:	95/152 - (62%)
Similarity:	114/152 - (75%)	Gaps:	3/152 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 EEPSYAFFLGCTGAAVAIIFTTLGASYGTAVSGVGIAKMAVNRPDMIMKAIIPVVMAGIIAIYGL 72
            |..:||.|.|..|||.|.|||.|||:||||.|.|||..|.|.||::|||::|||:|||||.||||
Worm     9 ERAAYAPFFGYMGAASAQIFTVLGAAYGTAKSAVGICSMGVMRPELIMKSVIPVIMAGIIGIYGL 73

  Fly    73 VVSVLIAG---SIGDDYTMEDSYVHLGAGLSVGLPGLTAGVAIGIAGDAGVRGTAEQPRLFVGMV 134
            ||::::.|   |....|.:...:.||.|||:.||.||.||.||||.|||||||||:||||||||:
Worm    74 VVAMVLKGKVTSASAGYDLNKGFAHLAAGLTCGLCGLGAGYAIGIVGDAGVRGTAQQPRLFVGMI 138

  Fly   135 LILIFAEVLALYGLIVAIYLYT 156
            |||||:|||.|||:|||:.|.|
Worm   139 LILIFSEVLGLYGMIVALILGT 160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vha16-2	NP_729707.1	PRK06558	14..158	CDD:235830	92/146 (63%)
		ATP-synt_C	15..120	CDD:294318	62/107 (58%)
		ATP-synt_C	94..154	CDD:278563	46/59 (78%)
vha-3	NP_001367642.1	V_ATP_synt_C	16..124	CDD:130170	62/107 (58%)
vha-3	NP_001367642.1	ATP-synt_Vo_c_ATP6C_rpt2	92..158	CDD:349416	46/65 (71%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0636
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	210	1.000	Inparanoid score	I2374
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53914
OrthoDB	1	1.010	-	-		D1534092at2759
OrthoFinder	1	1.000	-	-		FOG0001101
OrthoInspector	1	1.000	-	-		mtm4729
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10263
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X666
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.940