Protein Alignment Fum3 and FUM1

DIOPT Version :10

• Sequence 1: NP_648467.1
• Gene: Fum3 / 39281
• FlyBaseID: FBgn0036162
• Length: 470
• Species: Drosophila melanogaster
• Sequence 2: NP_015061.1
• Gene: FUM1 / 855866
• SGDID: S000006183
• Length: 488
• Species: Saccharomyces cerevisiae
• Alignment Length: 462
• Identity: 277/462 - (59%)
• Similarity: 351/462 - (75%)
• Gaps: 5/462 - (1%)

  Fly    10 RQESDTLGPMEVPMDRYYGAQTMRCLINFRIGGEEERMPRQIIQAMGILKKAAAETNQEF-GLDP 73
            |.|:|..|.:.||.|:|:||||.|...||:|||..||||..::.|.|:|||:||..|:.. ||||
Yeast    29 RTETDAFGEIHVPADKYWGAQTQRSFQNFKIGGARERMPLPLVHAFGVLKKSAAIVNESLGGLDP 93

  Fly    74 KLSTAISNAADDVISGKLYDEGHFPLPIWQTGSGTQSNMNSNEVIGNRAIELLGGRIGTKDPVHP 138
            |:|.||..|||:|.||||.|  ||||.::|||||||||||:||||.|||||:|||:||:|. |||
Yeast    94 KISKAIQQAADEVASGKLDD--HFPLVVFQTGSGTQSNMNANEVISNRAIEILGGKIGSKQ-VHP 155

  Fly   139 NDHVNKSQSSNDTFPSAIHIAVATALTKDLRPAVTALRDSLQAKSNEWKDIIKIGRTHTQDAVPL 203
            |:|.|:|||||||||:.:|||.:..:..:|.|.:|.|:::|:|||.|:..|:||||||.|||.||
Yeast   156 NNHCNQSQSSNDTFPTVMHIAASLQIQNELIPELTNLKNALEAKSKEFDHIVKIGRTHLQDATPL 220

  Fly   204 TLGQEFSGYAQQLTNGLQRIDAVLPRVYQLALGGTAVGTGLNTRRGFAEKCVKRIAQLSGLPFVV 268
            |||||||||.||:.||:||:...|..:..||.|||||||||||:.||..|..::|::.:||.|..
Yeast   221 TLGQEFSGYVQQVENGIQRVAHSLKTLSFLAQGGTAVGTGLNTKPGFDVKIAEQISKETGLKFQT 285

  Fly   269 APNFFEALACRDAMVEVHGALNVLAVSLMKVTNDIRFLGSGPRCGLGELFLPENEPGSSIMPGKV 333
            |||.|||||..||:||..||||.||.||.|:..|||:||||||||..||.|||||||||||||||
Yeast   286 APNKFEALAAHDAIVECSGALNTLACSLFKIAQDIRYLGSGPRCGYHELMLPENEPGSSIMPGKV 350

  Fly   334 NPTQCEAMTMICAQVMGNHVAVSVGGANGHFELNVFKPLIASNVLRSIKLLADGCISFNCNCVKG 398
            ||||.||:|.:|.|||||:.|::..|:.|.||||||||::.:|:|.||:|:.|...||..:||:|
Yeast   351 NPTQNEALTQVCVQVMGNNAAITFAGSQGQFELNVFKPVMIANLLNSIRLITDAAYSFRVHCVEG 415

  Fly   399 IKPNKEKLAKIVNESLMLVTALNPHIGYDKSAQIAKAAHKNGTTLKVEALNAGI-SEKDFNEWVR 462
            ||.|:.::.:::.:||||||||||.||||.::::||.|||.|.|||..||..|: :||:|:|||.
Yeast   416 IKANEPRIHELLTKSLMLVTALNPKIGYDAASKVAKNAHKKGITLKESALELGVLTEKEFDEWVV 480

  Fly   463 PEKMLGP 469
            ||.||||
Yeast   481 PEHMLGP 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Fum3	NP_648467.1	fumC	8..469	CDD:234779	275/460 (60%)
FUM1	NP_015061.1	FumC	26..486	CDD:439884	274/459 (60%)