Protein Alignment CG7551 and KHK

DIOPT Version :9

• Sequence 1: NP_648466.1
• Gene: CG7551 / 39280
• FlyBaseID: FBgn0036161
• Length: 322
• Species: Drosophila melanogaster
• Sequence 2: XP_006712071.1
• Gene: KHK / 3795
• HGNCID: 6315
• Length: 371
• Species: Homo sapiens
• Alignment Length: 330
• Identity: 80/330 - (24%)
• Similarity: 130/330 - (39%)
• Gaps: 103/330 - (31%)

  Fly    14 KKTVLCIGTTTIDFVSTIKRFPEENSHQKVIGGYWIRGGKASNNCTVLANLGVKVEFLGMLS--- 75
            :|.:||:|...:|.:|.:.::|:|:|..:.:...|.|||.|||:||||:.||....|:|.::
Human     3 EKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTVLSLLGAPCAFMGSMAPGH 67

  Fly    76 -----------------SWSVFQV--------------------------LVDDLKSRGIIIDNC 97
                             .::|||.                          ||.|.:.||:.:...
Human    68 VADSFVLDDLRRYSVDLRYTVFQTTGSVPIATVIINEASGSRTILYYDSFLVADFRRRGVDVSQV 132

  Fly    98 PTCDQG-APFSSVILTKATKTRNIVYCNNNFPYVSIDDFRKLNLNQYGWIHIRALYFDKSLPMVK 161
            ....:| .|.|..|:..:...|.||..:.:.|.||..||.|::|.|:.||||......:.:.|::
Human   133 AWQSKGDTPSSCCIINNSNGNRTIVLHDTSLPDVSATDFEKVDLTQFKWIHIEGRNASEQVKMLQ 197

  Fly   162 DIEAYNANR--KEKIVLSMEFDNNLDDMWPLMDYCDY--AVFSKKLAQP---------------- 206
            .|:|:|..:  ::||.:|:|.:...::::.|..|.|.  |.||..|..|
Human   198 RIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVGAPFSLSLPLPANLVLKGSQNPFILPT 262

  Fly   207 ------NGWVSLEDACMQLDER--------------------LRMRW----------GLNLKRPY 235
                  .|.|..||....|.:|                    |..||          .:.||:|.
Human   263 TIGIVVPGLVVFEDGGWGLKQRSRPLALGSSAGLSSEQGVECLHPRWVHRCKNAQRAWVGLKQPQ 327

  Fly   236 VVVLW 240
            ...:|
Human   328 GKPVW 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7551	NP_648466.1	Ketohexokinase	16..311	CDD:238914	79/328 (24%)
KHK	XP_006712071.1	ribokinase_pfkB_like	5..>235	CDD:294126	61/229 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158959
Domainoid	1	1.000	177	1.000	Domainoid score	I3600
eggNOG	1	0.900	-	-		E1_KOG2947
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	178	1.000	Inparanoid score	I4031
Isobase	1	0.950	-	0	Normalized mean entropy	S6304
OMA	1	1.010	-	-		QHG53391
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003629
OrthoInspector	1	1.000	-	-		otm41108
orthoMCL	1	0.900	-	-		OOG6_104955
Panther	1	1.100	-	-	O	PTHR43085
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4048
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.710