Protein Alignment CG12289 and Khk

DIOPT Version :10

• Sequence 1: NP_648465.2
• Gene: CG12289 / 39279
• FlyBaseID: FBgn0036160
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_001297453.1
• Gene: Khk / 16548
• MGIID: 1096353
• Length: 343
• Species: Mus musculus
• Alignment Length: 348
• Identity: 96/348 - (27%)
• Similarity: 158/348 - (45%)
• Gaps: 60/348 - (17%)

  Fly    11 KAVLCVGCTEVDYVTTMDKV-DFQCD-RCSTQNGMLQRSGRSSNVSTALRLLGANVELFGVLTRN 73
            |.:||||...:|.:..:||. :...| ||.:|.  .||.|.:||..|.|.||||.....|.|...
Mouse     4 KQILCVGLVVLDIINVVDKYPEEDTDRRCLSQR--WQRGGNASNSCTVLSLLGARCAFMGSLAPG 66

  Fly    74 PTYRMILDDLEQRGIDISHCTF-TDASPPFSTIV-----------------------------QD 108
            .....:||||.|..:|:.:... |:.|.|.||::                             |.
Mouse    67 HVADFVLDDLRQHSVDLRYVVLQTEGSIPTSTVIINEASGSRTILHAYSFLVADFRQRGVDVSQV 131

  Fly   109 RWTRR-------C---------TVVYCDKSFPYVTAADFRKLDLDQYGWVNFEARSPRETCDMIR 157
            .|..:       |         |::..|.:.|.|:|.||.|:||.::.|::.|.|:..|...|::
Mouse   132 TWQSQGDTPCSCCIVNNSNGSRTIILYDTNLPDVSAKDFEKVDLTRFKWIHIEGRNASEQVKMLQ 196

  Fly   158 LILDHNNGRDERDRIVVSLQIFNSFEQVVHLIAMCDYVFVTKYIAESRGWKSPLEACEGVNALLR 222
            .|.:||..:....::.||::|....|::..|.:..:.|||:|.:|:..|::|.:||..|:.:
Mouse   197 RIEEHNAKQPLPQKVRVSVEIEKPREELFQLFSYGEVVFVSKDVAKHLGFQSAVEALRGLYS--- 258

  Fly   223 MPRNIRIRRPCIIV-PWSSLGAGCMTTEGEYFEVPAHKPKKIIDRVGDSDCFTAGFIYAAFVRQR 286
                 |:::...:| .|:..||..:..:|:.....|..|.:::|.:|..|.|.|..|: :..:..
Mouse   259 -----RVKKGATLVCAWAEEGADALGPDGQLLHSDAFPPPRVVDTLGAGDTFNASVIF-SLSKGN 317

  Fly   287 RLAEAVDFANAVASYKLGYVGFD 309
            .:.||:.|...||..|.|..|||
Mouse   318 SMQEALRFGCQVAGKKCGLQGFD 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG12289	NP_648465.2	Ketohexokinase	12..309	CDD:238914	93/345 (27%)
Khk	NP_001297453.1	Ketohexokinase	5..340	CDD:238914	93/345 (27%)