Protein Alignment CG7560 and Mthfr

DIOPT Version :10

• Sequence 1: NP_648462.1
• Gene: CG7560 / 39276
• FlyBaseID: FBgn0036157
• Length: 349
• Species: Drosophila melanogaster
• Sequence 2: NP_001155270.1
• Gene: Mthfr / 17769
• MGIID: 106639
• Length: 695
• Species: Mus musculus
• Alignment Length: 270
• Identity: 70/270 - (25%)
• Similarity: 125/270 - (46%)
• Gaps: 38/270 - (14%)

  Fly    79 PTFVSFVWLSQRYWDVEPVG------QVESLQMAQHLAT--RIPVLPHVSAYRMSRQRLDQFL-- 133
            |.||...|        .|.|      :..|:.:|.....  .:..:.|::..:...:.:...|
Mouse   128 PLFVDVTW--------HPAGDPGSDKETSSMMIASTAVNYCGLETILHMTCCQQRPEEITGHLHR 184

  Fly   134 --ALNFSSLLAVRGDRV--H---EDQDFSISYPMVEQSIRQRGETISVCVGGYPEGYTSLGDIPQ 191
              .|...:::|:|||.|  |   |:..||.:..:|:....:..:...:||.|||.|:..    .:
Mouse   185 AKQLGLKNIMALRGDPVGDHWEAEEGGFSYATDLVKHIRTEFADYFDICVAGYPRGHPD----AE 245

  Fly   192 NSAKNMEFLKAKIDAGADCIITQLCYRPEVIVQFVKDCRAAGISVPIVVGLMSHESFRSYSMIEQ 256
            :...:::.||.|:.||||.|||||.:.......|||.|...|||.||:.|:...:.:.|...:.:
Mouse   246 SFEDDLKHLKEKVSAGADFIITQLFFEASTFFSFVKACTEIGISCPILPGIFPIQGYTSLRQLVK 310

  Fly   257 ITGVHLPDDLREQLDQLHSAHMKDMKSDQDLIRRFFVSLTVRTIRNVLDADVGVWGFHFFTLNRF 321
            ::.:.:|..:::.::.:        |.:...||.:.:.|.|...|.:||:.: |.|.||:||||.
Mouse   311 LSKLEVPQKIKDVIEPI--------KDNDAAIRNYGIELAVSLCRELLDSGL-VPGLHFYTLNRE 366

  Fly   322 KSVQAVLQEL 331
            .:...||::|
Mouse   367 VATMEVLKQL 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7560	NP_648462.1	MTHFR	76..331	CDD:238299	69/268 (26%)
Mthfr	NP_001155270.1	MTHFR	100..666	CDD:444783	70/270 (26%)