Protein Alignment CG7560 and mthf-1

DIOPT Version :10

• Sequence 1: NP_648462.1
• Gene: CG7560 / 39276
• FlyBaseID: FBgn0036157
• Length: 349
• Species: Drosophila melanogaster
• Sequence 2: NP_741027.1
• Gene: mthf-1 / 174254
• WormBaseID: WBGene00015512
• Length: 663
• Species: Caenorhabditis elegans
• Alignment Length: 331
• Identity: 80/331 - (24%)
• Similarity: 151/331 - (45%)
• Gaps: 52/331 - (15%)

  Fly    23 TFAPDQNESVVTKQRIGTLVAERTAQHRLFYGIEVMASDP---SGRPTCLDFNHFLPLL------ 78
            :::|...|  :..:||..|:.|:    :.|:.:|..  .|   :|.|      :||..:
 Worm    49 SWSPKHYE--LLHERIERLIDEK----QQFFSLEFF--PPRFVNGVP------NFLERVERLSEG 99

  Fly    79 -PTFVSFVW-LSQRYWDVEPVGQVESLQMAQHLATRIPVLPHVSAYRMSR----QRLDQFLALNF 137
             ..||...| :.....:|:.|....|:..:......:..:.|::..:.::    :.|:|..|:..
 Worm   100 GSVFVDMTWHMGSDPANVDKVTSSSSIAASMLDYCGVDTMLHMTCVQYNKADTLKHLEQAKAMGL 164

  Fly   138 SSLLAVRGD-----RVHEDQDFSISYPMVEQSIRQRGETISVCVGGYPEGYTSLGDIPQ--NSAK 195
            .|:||:|||     .:.:...|. :..|:.....:.|...|:...|||.|:      ||  :...
 Worm   165 RSILALRGDLPPGTELEDTHQFR-ALDMIRWIREEYGNYFSIGCAGYPLGH------PQAPSYKA 222

  Fly   196 NMEFLKAKIDAGADCIITQLCYRPEVIVQFVKDCRAAGISVPIVVGLMSHESFRSYSMIEQITGV 260
            ::.:||||.||||:.:||||.:..|...:||:|||..||:.||:.|:|....:.|...|.:::.:
 Worm   223 DLMYLKAKCDAGANFVITQLFFEAETFEKFVRDCREIGITQPIIPGIMPIMGYESIKRIAKLSQL 287

  Fly   261 HLPDDLREQLDQLHSAHMKDMKSDQDLIRRFFVSLTVRTIRNVLDADVGVWGFHFFTLNRFKSVQ 325
            .:|..:.:.|:.:        |.|.|.::::.....:...|.:||..... ..|.:|:||..|::
 Worm   288 EIPQHILDDLEPI--------KHDDDAVQKYGTERCIEMCRRLLDNGTAP-SIHLYTMNREGSIR 343

  Fly   326 AVLQEL 331
            .:|:.|
 Worm   344 EILKSL 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7560	NP_648462.1	MTHFR	76..331	CDD:238299	66/273 (24%)
mthf-1	NP_741027.1	MTHFR	73..644	CDD:444783	73/301 (24%)