DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11726 and NOP12

DIOPT Version :9

Sequence 1:	NP_648461.1	Gene:	CG11726 / 39275	FlyBaseID:	FBgn0036156	Length:	291	Species:	Drosophila melanogaster
Sequence 2:	NP_014601.1	Gene:	NOP12 / 854116	SGDID:	S000005401	Length:	459	Species:	Saccharomyces cerevisiae

Alignment Length:	286	Identity:	61/286 - (21%)
Similarity:	102/286 - (35%)	Gaps:	98/286 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 SSSVSSVSGSESGQGLEDMLHVTKVRTSQVDNAELFMYGDGP-----KKS-------NSDLQKKV 70
            ||::.::.|:...:.:|          |.||  :||....||     .||       :|..:::.
Yeast     2 SSAIDNLFGNIDEKKIE----------SSVD--KLFSSSCGPINKLEVKSKTRTVLPDSKKRERA 54

  Fly    71 STPDPEEEVSMEPPFVALVSNLPMECTEGELRKVFTSFSIRSLTIPKKGKRPKGFAYVEMDSRED 135
            :..|.||:.:.:|.    ||:...|  |..|.||            ||.|:.|     ..|..||
Yeast    55 AEADQEEKEASKPD----VSDEQTE--EVALPKV------------KKAKKSK-----RNDEDED 96

  Fly   136 L-----VRLLKMDKLKCRGRCLMAKIGQLPPEPPTKAAGDGFSL-FTCSGRQFDINSSHYSASV- 193
            |     .:||..:             .:...:.||....|..|: .|.:.::.|........:.
Yeast    97 LEARYYAKLLNEE-------------AEAEDDKPTVTKTDETSVPLTSAAKKVDFKEDELEKAER 148

  Fly   194 -----SDLSTIDSPISARNSPFPSESESSFFGRDNPIKRIPSSTEEVERRMQIRLQKLAEFENS- 252
                 :.|||:   |:::.   ..:.....|| .|||.....|..|.|.      :...:.:|:
Yeast   149 TVFIGNILSTV---ITSKK---VYKEFKKLFG-TNPIAETEESGNEKEE------ESSKKSDNNE 200

  Fly   253 ---ESERIKSECEDDPDAFMSWSDAL 275
               ||.|.:|         :|:.:||
Yeast   201 FAIESIRFRS---------ISFDEAL 217

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11726	NP_648461.1	RRM_SF	84..156	CDD:302621	17/76 (22%)
NOP12	NP_014601.1	RRM1_Nop12p_like	148..272	CDD:410070	20/92 (22%)
NOP12	NP_014601.1	RRM2_Nop12p_like	280..370	CDD:410071
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23236
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100