Protein Alignment CG11726 and EIF4B

DIOPT Version :9

• Sequence 1: NP_648461.1
• Gene: CG11726 / 39275
• FlyBaseID: FBgn0036156
• Length: 291
• Species: Drosophila melanogaster
• Sequence 2: NP_001287750.1
• Gene: EIF4B / 1975
• HGNCID: 3285
• Length: 616
• Species: Homo sapiens
• Alignment Length: 416
• Identity: 68/416 - (16%)
• Similarity: 114/416 - (27%)
• Gaps: 193/416 - (46%)

  Fly    11 FKLPPVSSSSVSSVSGSESGQGLEDMLHVTKVRTSQVDNAELFMYGDGPKKSNSDLQKKVSTPDP 75
            ::.||:..|.:.:...:              .|...:|.:.|      ||
Human    63 YRAPPIDRSILPTAPRA--------------AREPNIDRSRL------PK--------------- 92

  Fly    76 EEEVSMEPPFVALVSNLPMECTEGELRKVFTSFSIRSLTIPKKGKRP---KGFAYVEMDSREDLV 137
                  .||:.|.:.|||.:.||..:::.|...:|.::.:|::...|   |||.|.|.:..:.|:
Human    93 ------SPPYTAFLGNLPYDVTEESIKEFFRGLNISAVRLPREPSNPERLKGFGYAEFEDLDSLL 151

  Fly   138 RLLKMDKLKCRGRCLMAKIG--------------------------------------QLPPEPP 164
            ..|.:::.....|.:...:.                                      ..||...
Human   152 SALSLNEESLGNRRIRVDVADQAQDKDRDDRSFGRDRNRDSDKTDTDWRARPATDSFDDYPPRRG 216

  Fly   165 TKAAGD----------------------------------------------GFSLFTCSGR--- 180
            ..:.||                                              |:.....|||
Human   217 DDSFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRAF 281

  Fly   181 -------------------QFDINSSHYSASVSDLSTIDSPISARNSP-----------FPSESE 215
                               ::|.......:|..|.|..|.....|..|           .|.|.:
Human   282 GSGYRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDYSRDDYRRDDRGPPQRPKLNLKPRSTPKEDD 346

  Fly   216 S-----------SFFGRDNPIKRIPSSTEEVERRMQIRLQKLAEFENSESERIKSECEDDP---- 265
            |           |.||...|:     .|...||.::.||||       |.|:::.:. |:|
Human   347 SSASTSQSTRAASIFGGAKPV-----DTAAREREVEERLQK-------EQEKLQRQL-DEPKLER 398

  Fly   266 ---DAFMSW-SDALDEIRKSETDSSN 287
               :...|| |:...|..:|.|.|.:
Human   399 RPRERHPSWRSEETQERERSRTGSES 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11726	NP_648461.1	RRM_SF	84..156	CDD:302621	19/74 (26%)
EIF4B	NP_001287750.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..37
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	66..93		8/67 (12%)
		RRM	<83..>190	CDD:223796	24/133 (18%)
		RRM_eIF4B	95..171	CDD:240848	19/75 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1530583at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920