Protein Alignment CG11726 and SRSF12

DIOPT Version :10

• Sequence 1: NP_648461.1
• Gene: CG11726 / 39275
• FlyBaseID: FBgn0036156
• Length: 291
• Species: Drosophila melanogaster
• Sequence 2: NP_542781.3
• Gene: SRSF12 / 135295
• HGNCID: 21220
• Length: 261
• Species: Homo sapiens
• Alignment Length: 183
• Identity: 46/183 - (25%)
• Similarity: 72/183 - (39%)
• Gaps: 39/183 - (21%)

  Fly    83 PPFVAL-VSNLPMECTEGELRKVFTSFS-IRSLTIPKK--GKRPKGFAYVEM-DSREDLVRLLKM 142
            ||..:| :.|:.......:||:.|..:. |..:.||..  .:||:|||||:. |.|:....|..:
Human     7 PPNTSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQFEDVRDAEDALYNL 71

  Fly   143 DKLKCRGRCLMAKIGQLPPEPPTKAAGDGFSLFTCSGRQFDINSSHYSASVSDLSTIDSPISARN 207
            ::....||.:..:..|...:.|.:..                :...:..|.||.....||...|
Human    72 NRKWVCGRQIEIQFAQGDRKTPGQMK----------------SKERHPCSPSDHRRSRSPSQRR- 119

  Fly   208 SPFPSESESSFFGRDNPIKRIPSSTEEVERRMQIRLQKLAEFENSESE-RIKS 259
                :.|.||.:||:.  :|..|..|...||          |..|:|: |.||
Human   120 ----TRSRSSSWGRNR--RRSDSLKESRHRR----------FSYSQSKSRSKS 156

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11726	NP_648461.1	RRM_SF	83..150	CDD:473069	20/71 (28%)
SRSF12	NP_542781.3	RRM_SRSF10_SRSF12	10..93	CDD:240758	21/82 (26%)
		PABP-1234	<12..211	CDD:130689	44/178 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	86..261		24/104 (23%)