DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6168 and qpctla

DIOPT Version :9

Sequence 1:	NP_001287032.1	Gene:	CG6168 / 39273	FlyBaseID:	FBgn0036154	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	NP_001038418.1	Gene:	qpctla / 561142	ZFINID:	ZDB-GENE-030131-1441	Length:	392	Species:	Danio rerio

Alignment Length:	367	Identity:	130/367 - (35%)
Similarity:	196/367 - (53%)	Gaps:	50/367 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 IALICL--AIIVVVITICQSFHTNFLTVGRNGT------------LRYEPTELNLGQMRMIAGLS 58
            :.|:||  |:.:.:|...      :|:...:|:            |.::|.:.::.|.:.:||..
Zfish    33 LLLLCLCGALSLAMILAL------YLSAEPSGSLLPHPADLIKDRLSHKPNKYSVAQAKKLAGQV 91

  Fly    59 DPENL-RKNVQRIAIKRAVSTPGHSEVRNYIVDYLKKLN--WNVELDIFTQKVPIMSNVTFHNIV 120
            |...| ..:::.:.|:|...|.|...:|.:|:..|:.|:  |.:|.:.|....| ..:|||.|::
Zfish    92 DGHRLWETHLRPLLIERVPGTTGSQIIRQHILSQLRSLSAGWTLEENDFVSSTP-KGDVTFTNLL 155

  Fly   121 ARQNPQTQRYLMFGCHYDSKYF----KDFD--FMAATDSAVPCALMLNMATILKHQF-----HRS 174
            |..:|...|.|:..||:|||..    |:..  |:.|:|||||||::|.:|:.|..|.     .||
Zfish   156 AVLDPSAPRRLLLACHHDSKIIPADPKNSKRVFVGASDSAVPCAIILELASALDKQLKALKQQRS 220

  Fly   175 QVSLMLVFFDGEEAFGEWSQEDSPYGSRHLAELWE---------KHGFLDKIDLFVLPDLIGAKD 230
            .|:|.||||||||||.||:..||.|||||||||..         |...|..:||.||.||:||.:
Zfish   221 AVTLQLVFFDGEEAFEEWTDTDSLYGSRHLAELMSRTPHPAGSTKSSLLQAVDLLVLLDLLGAPE 285

  Fly   231 VVFKKNILDTSGWFHRLVQLELKLFQAGIVR---SERPLFK--FEPGIDVDDDHLPFTRRNVPVI 290
            .:...:..:|:.||.||:..|.:|.:.|::.   ||:..|:  |..| .|.|||:||..|.|||:
Zfish   286 PLIVNHFDNTARWFDRLIAAEKRLHKQGLLTSHPSEQSYFRKDFYLG-PVQDDHIPFLNRGVPVL 349

  Fly   291 HLISNKYPAVWHQAEDVEMNVDYNTTEQVGLVLRMFVMEYLN 332
            |||...:|..||..:|||..:...|.|.:..:|.:||.|||:
Zfish   350 HLIPTPFPVFWHTLDDVEERMHRPTVENLTRILAIFVAEYLS 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6168	NP_001287032.1	M28_QC_like	49..330	CDD:193501	118/308 (38%)
qpctla	NP_001038418.1	M28_QC_like	82..389	CDD:193501	118/308 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577741
Domainoid	1	1.000	42	1.000	Domainoid score	I12432
eggNOG	1	0.900	-	-		E1_KOG3946
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	243	1.000	Inparanoid score	I3283
OMA	1	1.010	-	-		QHG55920
OrthoDB	1	1.010	-	-		D1257754at2759
OrthoFinder	1	1.000	-	-		FOG0001509
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12283
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1074
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.870