DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6168 and H27A22.1

DIOPT Version :9

Sequence 1:	NP_001287032.1	Gene:	CG6168 / 39273	FlyBaseID:	FBgn0036154	Length:	342	Species:	Drosophila melanogaster
Sequence 2:	NP_001041144.1	Gene:	H27A22.1 / 179482	WormBaseID:	WBGene00010418	Length:	356	Species:	Caenorhabditis elegans

Alignment Length:	353	Identity:	120/353 - (33%)
Similarity:	190/353 - (53%)	Gaps:	24/353 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 WRSFIALICLAIIVVVITICQSFHTNFLTVGRNGTLRYEPTELNLGQMRMIAGLSDPENLRKNVQ 68
            ||....|:.||:::.::....|....:.|..|...|...|....|   |:....::....::.:.
Worm     8 WRLIFVLMGLALVLGILICTTSAWGQWRTNQRTHQLSLLPESSTL---RLCRDFTNTTRFKEILA 69

  Fly    69 RIAIKRAVSTPGHSEVRNYIVDYLKKLNWNVELDIFTQKVPIMSNVTFHNIVARQNPQTQRYLMF 133
            .|.:.|.|.|..|.:|.:|:..:|..|.:..|.|.||...|:.:. .|.|::|..:....|.|:.
Worm    70 PIMVPRIVDTKQHRQVGDYLQSFLHNLGFATEWDAFTDTTPLGTR-NFRNLIATFDESAPRRLVL 133

  Fly   134 GCHYDSKYFKDFDFMAATDSAVPCALMLNMA-TILKHQFHR--SQVSLMLVFFDGEEAFGEWSQE 195
            .||||||.......:||||||||||:||::| |:..:.:.|  .|:.|.|:||||||||.:|:..
Worm   134 ACHYDSKIIPGQVMIAATDSAVPCAMMLDIAQTLAPYMYKRVAQQIGLQLIFFDGEEAFRDWTAT 198

  Fly   196 DSPYGSRHLAELWEKHGF--------------LDKIDLFVLPDLIGAKDVVFKKNI-LDTSGWFH 245
            ||.|||||||:.||:..:              ||:||:.:|.||:||.:......| :..:..|.
Worm   199 DSLYGSRHLAQKWEQKWYPSSSSLNNFELSKELDRIDVLMLLDLLGAANPSIGNTIGMGANDLFS 263

  Fly   246 RLVQLELKLFQAGIVRS-ERPLFKFEPGID-VDDDHLPFTRRNVPVIHLISNKYPAVWHQAEDVE 308
            :|..:|..|..:|.:.| .|.:|..:...: |:|||:||.:|.||::|||:..:|:|||::.|..
Worm   264 QLADVESNLRTSGCLSSLRRNVFNKQLSYNQVEDDHIPFLKRGVPILHLITVPFPSVWHRSSDNA 328

  Fly   309 MNVDYNTTEQVGLVLRMFVMEYLNSAPS 336
            ..:.|.|.:.:..|:|:||.:||..||:
Worm   329 NALHYPTIDHMTAVIRVFVAKYLGIAPA 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6168	NP_001287032.1	M28_QC_like	49..330	CDD:193501	105/300 (35%)
H27A22.1	NP_001041144.1	M28_QC_like	50..350	CDD:349876	106/303 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55920
OrthoDB	1	1.010	-	-		D1257754at2759
OrthoFinder	1	1.000	-	-		FOG0001509
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12283
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1074
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.030