Protein Alignment CG7573 and STE24

DIOPT Version :10

• Sequence 1: NP_729695.2
• Gene: CG7573 / 39272
• FlyBaseID: FBgn0036153
• Length: 477
• Species: Drosophila melanogaster
• Sequence 2: NP_012651.1
• Gene: STE24 / 853581
• SGDID: S000003878
• Length: 453
• Species: Saccharomyces cerevisiae
• Alignment Length: 458
• Identity: 92/458 - (20%)
• Similarity: 179/458 - (39%)
• Gaps: 86/458 - (18%)

  Fly    53 SFHLILCCRQLKLCKRTSVPPKQMEGILSQEAFQASKDKQLHASSLEIF----NIAIDTLYSCLD 113
            ||...|..||.:....|.:|| .:|..:..|.|..|::.....:...||    |:|...::...|
Yeast    28 SFESYLTYRQYQKLSETKLPP-VLEDEIDDETFHKSRNYSRAKAKFSIFGDVYNLAQKLVFIKYD 91

  Fly   114 LYLCTLAFLWKLTVGW--------YHYADSTWLNVTFMTVFSTYLVVRKLPSLFYEKLVLDPRYN 170
            |:    ..:|.:.|..        :|...:...::.|:.:.|:...:..||..:|...||:.::.
Yeast    92 LF----PKIWHMAVSLLNAVLPVRFHMVSTVAQSLCFLGLLSSLSTLVDLPLSYYSHFVLEEKFG 152

  Fly   171 VDPEKTPPLLGLICALVFVVVFLQVAVI---PLTAIFMAI------HMLSEWYFTLFVWLGLVGL 226
            .:.      |.:...:..::..|.:|..   |:..:|:.|      ..|  ||..:|:::    :
Yeast   153 FNK------LTVQLWITDMIKSLTLAYAIGGPILYLFLKIFDKFPTDFL--WYIMVFLFV----V 205

  Fly   227 SVLVLAFVGLFGVPCLGKSRKMNSTDMDNSLKAVLDDFNFP-GRVYMV---------HTFHVGRP 281
            .:|.:..:.:|.:|...|...:...::..|::::.|...|| .:::::         :.:..|.|
Yeast   206 QILAMTIIPVFIMPMFNKFTPLEDGELKKSIESLADRVGFPLDKIFVIDGSKRSSHSNAYFTGLP 270

  Fly   282 TAWVMGCCCCLRLDIHDNLKWNRGFSSDDFDWGQMGAGLNDEQLAAFVAHQLAHWQLWHVAKGLA 346
            ..       ..|:.:.|.|     .:|:..|           ::.|.:||::.|||..|:...:.
Yeast   271 FT-------SKRIVLFDTL-----VNSNSTD-----------EITAVLAHEIGHWQKNHIVNMVI 312

  Fly   347 LIYFYLLIYLLLFGICNRWITLYAAAGF--------------TTFYPSSVGFWLVYKYLMPIYHD 397
            ....:..:...||....|..:.|...||              |..:|..:||.|....|.|: ..
Yeast   313 FSQLHTFLIFSLFTSIYRNTSFYNTFGFFLEKSTGSFVDPVITKEFPIIIGFMLFNDLLTPL-EC 376

  Fly   398 ISTWIVFFCIRHFEYAADAYVNRRGYGLPMRAALLKLFSDDYEFPYVDQCYLMWHRLRPSVLQRI 462
            ...:::....|..||.||||..:.||...:..||:.|...:.....||..|..:|...|::.:|:
Yeast   377 AMQFVMSLISRTHEYQADAYAKKLGYKQNLCRALIDLQIKNLSTMNVDPLYSSYHYSHPTLAERL 441

  Fly   463 DNL 465
            ..|
Yeast   442 TAL 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7573	NP_729695.2	Peptidase_M48_M56	42..467	CDD:333718	92/458 (20%)
STE24	NP_012651.1	M48A_Zmpste24p_like	17..446	CDD:320702	92/458 (20%)