Protein Alignment Ir68a and gria1a

DIOPT Version :9

• Sequence 1: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_991161.1
• Gene: gria1a / 798689
• ZFINID: ZDB-GENE-020125-1
• Length: 914
• Species: Danio rerio
• Alignment Length: 917
• Identity: 160/917 - (17%)
• Similarity: 288/917 - (31%)
• Gaps: 319/917 - (34%)

  Fly     2 RCLWILIVAFISLAMATSIP--IPIANPAPLSGYEMQL------------KILLQ-KILWVAN-- 49
            |.|.:|..:|:.|...:|.|  |.|....|...:|.::            |::.| .::.:.|
Zfish     3 RSLTLLCTSFLGLCFGSSFPSNINIGGLFPTESHEYEVFRFALSHHQDIPKLVPQVDMVKLGNSF 67

  Fly    50 ----------VKRCFAVITDDLHYPIYDR----IFFESVGRR----VIPFFVMRTNESDDLQ-RP 95
                      .|..:|:|      .:|||    :.....|..    |.|.|.|..:....:| ||
Zfish    68 SMTYAFCSQFSKGVYAII------GVYDRKTVNMLMSFCGALHVCFVTPSFPMENSNQFVIQLRP 126

  Fly    96 SRQVELFVKAIK-----------SSDCELNVITIL------NGWQV----------QRFLGYIYD 133
            ..| :..|..|:           |||..|:|:..:      :.|.|          ..||....|
Zfish   127 ELQ-DALVGVIEHYRWSKFVYMYSSDSGLSVLQKVLDTAAEHNWLVTSVNVETMTEASFLKVFQD 190

  Fly   134 ---------------NRSLNMQKKFV-----------LLHDLRLFESDM---------------- 156
                           .|..::.||.:           :|.:|...:.|:
Zfish   191 LDKKKEGQIIIDCELERLTSILKKIIELGKNVKSYHYILANLGFLDIDLTEFKKGEANVTGFQLV 255

  Fly   157 ----------IHLWSVF--IDAIFLKRQLDNKYTISTIAFPGILSGVLVMKNI------------ 197
                      :..|..|  .||...||:|  ||| ..:.:.|:.......:|:
Zfish   256 NYADPNVSRTVQQWMEFDNKDAKVPKRRL--KYT-GALTYDGVKVMSTAFQNLRRQRIDISRRGN 317

  Fly   198 ---------ANWELG------------KGLNGRILFADK-------------------------- 215
                     |.|..|            :||.|.|.|.:|
Zfish   318 AGECLANPPAPWGQGIDIQRALQQVRIEGLTGHIQFNEKGRRTNYSISVMELRPTGPKKVGYWNE 382

  Fly   216 -------------TSNLFG----TSLPVAISEHVPMVLWAN-----ATKSFQGVEVEIMNALGKA 258
                         ::..:|    |.:...|.|...::|..|     ....::|..||:...:.|.
Zfish   383 DEKFVSTAAYMPGSNETYGLQNRTYIVTTILESPYVMLKKNHEHFTGNDKYEGYCVELAAEIAKH 447

  Fly   259 LNFKPVY-------YKPNQTENMDWTELDGGASVAYGSGNPDGYAQNGTHIDSMLVDEVAAHSAR 316
            :.:..:.       |.....|.|.|                     ||      :|.|:....|.
Zfish   448 VGYHYILKIVADGKYGARDAETMMW---------------------NG------MVGELVYGKAD 485

  Fly   317 FAIGDLHLFQVYLKLVELSAPHNFECLTFL--TPESSTDNSWQTFILPFSAGMWVGVLLSLFVVG 379
            .|:..|.:..|..::::.|.|.....::.:  .|..|....: :|:.|.:..:|:.::.:...|.
Zfish   486 VAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPTKSKPGVF-SFLDPLAYEIWMCIVFAYIGVS 549

  Fly   380 TVFYAISFLN------------AIINGNVSSEFFRCLRPNRNVPMDPKIYRRISFRIAISRYRSS 432
            .|.:.:|..:            |..|.|..|.  ...:|.:|                 .:.::.
Zfish   550 VVLFLVSRFSPYEWHADDCEDGAEENPNQPSS--SSAQPGQN-----------------QQNQNQ 595

  Fly   433 KGDRMPRDLFDGYTNCILLTYSMLLYVALPRMPRNWPLRVLTGWYWIYCILLVATYRASFTAILA 497
            :......:.  |..|.:..:....:.......||:...|::.|.:|.:.::::::|.|:..|.|.
Zfish   596 QSQEQTNEF--GIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLT 658

  Fly   498 NPAARVTIDTLEDLLR-SHIPPST-GATENRQFFLEANDEVARKVGEKME-----VFGYSDD--- 552
            .......|::.|||.: :.|...| .|...::||..:...|..|:...|:     ||..:.|
Zfish   659 VERMVSPIESAEDLAKQTEIAYGTLDAGSTKEFFRRSKIAVFEKMWSYMKSADPSVFVKTTDEGV 723

  Fly   553 LTSRIAKGQCAYYDNEFYLRYLRV------------ADESGSALHIMKECVLYMPVVLAMEKNSA 605
            :..|.:||:.||........|:..            .|..|..              :|..|.|.
Zfish   724 MRVRKSKGKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYG--------------IATPKGSP 774

  Fly   606 LKPRVDASIQHLAEGGLI----AKWLKDAIEHLPAEALAQQE-ALMNIQKFWSSFVALLIGYVIS 665
            |:..|:.::..|.|.||:    .||..|..|.......::.: :.:::......|..|:.|..::
Zfish   775 LRNPVNLAVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILIGGLGLA 839

  Fly   666 MLTLLAE 672
            ||..|.|
Zfish   840 MLVALVE 846

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68a	NP_648455.2	Lig_chan	429..661	CDD:278489	49/258 (19%)
gria1a	NP_991161.1	Periplasmic_Binding_Protein_Type_1	26..387	CDD:299141	60/370 (16%)
		ANF_receptor	36..369	CDD:279440	58/342 (17%)
		PBP2_iGluR_AMPA_GluR1	404..806	CDD:270447	83/464 (18%)
		Lig_chan	536..836	CDD:278489	59/334 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591162
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740