Protein Alignment Ir68a and Grik2

DIOPT Version :10

• Sequence 1: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_062182.1
• Gene: Grik2 / 54257
• RGDID: 2733
• Length: 908
• Species: Rattus norvegicus
• Alignment Length: 656
• Identity: 133/656 - (20%)
• Similarity: 230/656 - (35%)
• Gaps: 185/656 - (28%)

  Fly    65 IYDRIFFESVGRRVIPFFVMRTNESDDLQRPSRQVELFVKAIKSSDCELNVITILNGWQVQRFLG 129
            :||.:...||..:..|...:.:.:. :..:|.|....|:..||.:.           |  :...|
  Rat   323 MYDAVHVVSVAVQQFPQMTVSSLQC-NRHKPWRFGTRFMSLIKEAH-----------W--EGLTG 373

  Fly   130 YIYDNRSLNMQKKFVLLHDLRLFESDMIHLWSVFIDAIFLKRQLDNKYTISTIAFPGILSGVLVM 194
            .|..|::..::..|.|                   |.|.||.:                    .:
  Rat   374 RITFNKTNGLRTDFDL-------------------DVISLKEE--------------------GL 399

  Fly   195 KNIANWELGKGLN------GRILFADKTSNLFGTSLPVAISEHVPMVLWANATK------SFQGV 247
            :.|..|:...|||      |:.  |:.|.:|...||.|......|.||:..:.|      .|:|.
  Rat   400 EKIGTWDPASGLNMTESQKGKP--ANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGY 462

  Fly   248 EVEIMNALGKALNFKPVYYKPNQTENMDWTELDGGASVAYGSGNPDGYAQNGTHIDSMLVDEVAA 312
            .::::..|...|.|.   |:....|       ||    .||:.:......||      :|.|:..
  Rat   463 CIDLLRELSTILGFT---YEIRLVE-------DG----KYGAQDDVNGQWNG------MVRELID 507

  Fly   313 HSARFAIGDLHLFQVYLKLVELSAPHNFECLTFLT--------PESSTDNSWQTFILPFSAGMWV 369
            |.|..|:..|.:..|..|:::.|.|       |:|        ..:.|:....:|:.|.|..:|:
  Rat   508 HKADLAVAPLAITYVREKVIDFSKP-------FMTLGISILYRKPNGTNPGVFSFLNPLSPDIWM 565

  Fly   370 GVLLSLFVVGTVFYAISFLNAIINGNVSSEFFRCLRPNRNVPMDPKIYRRISFRIAISRYRSSKG 434
            .|||:...|..|.:.|:..:.          :....|:   |.:|
  Rat   566 YVLLACLGVSCVLFVIARFSP----------YEWYNPH---PCNP-------------------- 597

  Fly   435 DRMPRDLFDGYTNCILLTYSMLLYVALPR-----MPRNWPLRVLTGWYWIYCILLVATYRASFTA 494
               ..|:.:  .|..||........||.|     ||:....|::.|.:|.:.::::::|.|:..|
  Rat   598 ---DSDVVE--NNFTLLNSFWFGVGALMRQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAA 657

  Fly   495 ILANPAARVTIDTLEDLLRSHIPPSTGATEN---RQFFLEANDEVARKVG--EKMEVFGYSDDLT 554
            .|........||:.:||.: ......||.|:   ..||.::      |:.  :||..|     ::
  Rat   658 FLTVERMESPIDSADDLAK-QTKIEYGAVEDGATMTFFKKS------KISTYDKMWAF-----MS 710

  Fly   555 SRIAKGQCAYYDNEFYLRYLRVAD-----ESGSALHI-MKECVLYMPVVLAMEK--------NSA 605
            ||  :.......||..::.:..:|     ||.:...: .:.|.|.....|...|        .|.
  Rat   711 SR--RQSVLVKSNEEGIQRVLTSDYAFLMESTTIEFVTQRNCNLTQIGGLIDSKGYGVGTPMGSP 773

  Fly   606 LKPRVDASIQHLAEGGLI----AKWLKDAIEHLPAEALAQQEALMNIQKFWSSFVALLIGYVISM 666
            .:.::..:|..|.|.|.:    .||.:.  ...|.|...:..|| .:|.....|:.|..|.|:|:
  Rat   774 YRDKITIAILQLQEEGKLHMMKEKWWRG--NGCPEEESKEASAL-GVQNIGGIFIVLAAGLVLSV 835

  Fly   667 LTLLAE 672
            ...:.|
  Rat   836 FVAVGE 841

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68a	NP_648455.2	Lig_chan	367..661	CDD:459656	64/321 (20%)
Grik2	NP_062182.1	PBP1_iGluR_Kainate	37..414	CDD:380605	25/143 (17%)
		Periplasmic_Binding_Protein_Type_2	430..800	CDD:473866	93/448 (21%)