Protein Alignment Ir68a and GluRIB

DIOPT Version :9

• Sequence 1: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_001261621.2
• Gene: GluRIB / 44484
• FlyBaseID: FBgn0264000
• Length: 1182
• Species: Drosophila melanogaster
• Alignment Length: 893
• Identity: 167/893 - (18%)
• Similarity: 296/893 - (33%)
• Gaps: 314/893 - (35%)

  Fly    42 QKILWVANVKRCFAV-ITDDLHYPIYDRIFFESVGRRVIPFF-----VMRTNESDDLQRP---SR 97
            :|:|..::....||: :..|.|..|.|.|.|.. .|::|..:     ::|..:.....||   |.
  Fly   137 EKVLTPSSGFLDFALSMRPDYHQAIIDTIQFYG-WRKIIYLYDSHDGLLRLQQIYQGLRPGNESF 200

  Fly    98 QVELFVKAIKSSDCELNVITILNGWQVQRFLGYIYDNRSL------NMQKKFVLLH--DLRL--- 151
            |||| ||.|.:....:..:..|.  |:.||     :|:.:      .|.|:.::.|  ||||
  Fly   201 QVEL-VKRISNVSMAIEFLHTLE--QIGRF-----ENKHIVLDCPTEMAKQILIQHVRDLRLGRR 257

  Fly   152 --------------FESDMIHLWSVFI-------------------------------------- 164
                          :||::|...::.|
  Fly   258 TYHYLLSGLVMDDRWESEIIEFGAINITGFRIVDTNRRLVREFYDSWKRLDPQMSVGAGRESISA 322

  Fly   165 ------DAIFLKRQLDNK---------------------------------YTISTI-------- 182
                  ||:|:..:..||                                 |..|..
  Fly   323 QAALMYDAVFVLVEAFNKILRKKPDQFRNNVQRRSQTLMVAQAAASTSSDGYNYSASGGGGGNGG 387

  Fly   183 ---AFPGILSG-----------VLVMKNIAN-WELG------------KGLNGRILFADKTSNLF 220
               .|.|..||           ....|...| ||.|            :||.|.|.|.|....:.
  Fly   388 AGGGFAGSDSGGSGGMASRALDCNTAKGWVNAWEHGDKISRYLRKVEIEGLTGDIKFNDDGRRVN 452

  Fly   221 GTSLPVAISEHVPMVLWANATKSFQGVEVEIMNALGKALNFKP-VYYKPNQTENMDWTELDGG-- 282
            .|...|.::.:..||..|...   ....::.:||  |.:..:| |.::.|:|..:. |.|:..
  Fly   453 YTLHVVEMTVNSAMVKVAEWN---DDAGLQPLNA--KYVRLRPHVEFEKNRTYIVT-TVLEEPYI 511

  Fly   283 --ASVAYGS---GNP--DGYAQN---------GTHIDSMLV-------DEVAAH----------- 313
              ..||:|.   ||.  :||.::         |.:.:..||       ::.:||
  Fly   512 MLKQVAFGEKLHGNNRFEGYCKDLADLLAKELGINYELRLVKDGNYGSEKSSAHGGWDGMVGELV 576

  Fly   314 --SARFAIGDLHLFQVYLKLVELSAPHNFECLTFL--TPESSTDNSWQTFILPFSAGMWVGVLLS 374
              .|..||..:.:.....::::.|.|.....::.:  .|...|...: :|:.|.|..:||.|:.|
  Fly   577 RKEADIAIAAMTITAERERVIDFSKPFMSLGISIMIKKPVKQTPGVF-SFMNPLSQEIWVSVIFS 640

  Fly   375 LFVVGTVFYAISFLNAIINGNVSSEFFRCL--RPNRNVPMDPKIYRR------------------ 419
            ...|..|.:.:|        ..|...:|.:  :|.::...||..:..
  Fly   641 YIGVSIVLFFVS--------RFSPHEWRLVQQQPQQSQSPDPHAHHEQLANQQPPGIIGGAPLPA 697

  Fly   420 ---------------ISFRIAISRYRSSKGDRMPRDLFDGYTNCILLTYSM----------LLYV 459
                           .:.:.|:|......|         |.::.::..:|:          .:..
  Fly   698 PPGPPTPGAQTAAGAAALQAALSAGSPGSG---------GSSSAVVNEFSVWNSFWFSLAAFMQQ 753

  Fly   460 ALPRMPRNWPLRVLTGWYWIYCILLVATYRASFTAILANPAARVTIDTLEDL-LRSHIPPST--- 520
            .....||:...|:....::.:.::|:::|.|:..|.|........|::.||| :::.:...|
  Fly   754 GCDLSPRSVSGRIAAASWFFFTLILISSYTANLAAFLTVERMVTPINSPEDLAMQTEVQYGTLLH 818

  Fly   521 GATENRQFFLEANDEVARKVGEKM----EVF--GYSDDLTS-RIAKGQCAYY----DNEFY---- 570
            |:|.:  ||..:...:..|:.|.|    .||  .|.:.:.. |.:||:.|..    .||:.
  Fly   819 GSTWD--FFRRSQIGLHNKMWEYMNSRKHVFVPTYDEGIKRVRNSKGKYALLVESPKNEYVNARE 881

  Fly   571 ----LRYLRVADESGSALHIMKECVLYMPVVLAMEKNSALKPRVDASIQHLAEGG----LIAKWL 627
                ::..|..|..|..              :|....||||..::.::..|.|.|    |..||.
  Fly   882 PCDTMKVGRNLDTKGFG--------------IATPLGSALKDPINLAVLTLKENGELIKLRNKWW 932

  Fly   628 KDAIE---HLPAEALAQQEALMNIQKFWSSFVALLIGYVISMLTLLAE 672
            .:..|   |...|....:.:|.|:.   ..|..|:.|.::|:...:.|
  Fly   933 YEKAECSTHKDGETSHSELSLSNVA---GIFYILIGGLLVSVFVAILE 977

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68a	NP_648455.2	Lig_chan	429..661	CDD:278489	53/271 (20%)
GluRIB	NP_001261621.2	PBP1_iGluR_AMPA	43..478	CDD:107375	66/352 (19%)
		ANF_receptor	55..461	CDD:279440	63/332 (19%)
		PBP2_iGluR_AMPA	497..938	CDD:270433	86/475 (18%)
		Lig_chan	632..967	CDD:278489	67/370 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462516
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740