Protein Alignment Ir68a and Ekar

DIOPT Version :10

• Sequence 1: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Alignment Length: 662
• Identity: 130/662 - (19%)
• Similarity: 245/662 - (37%)
• Gaps: 172/662 - (25%)

  Fly   123 QVQRFLG----YIYDNRSLNMQ-KKFVLLHDLRLFESDMIHLW-SVFIDAIFLKRQLDNKYTIST 181
            |:.:.:|    :|:....||:. ||..:|      ||:...:: ||::.||.| :.|:..::::.
  Fly   263 QILKDIGLYSHHIFKKPYLNLHIKKSTIL------ESEPALMFDSVYVFAIGL-QTLEQSHSLTL 320

  Fly   182 I--------AFPGILSGVLVMKNIANWELGKGLNGRILFADKTSNLFGTSLPVAISEH--VPMVL 236
            :        ::.|.|| ::...|...|   |||.|.|.|.|.....|...| :.:.:|  |.:..
  Fly   321 LNISCEEENSWDGGLS-LINYLNAVEW---KGLTGPIQFKDGQRVQFKLDL-IKLKQHSIVKVGE 380

  Fly   237 WA-------------------NAT-----------------KSFQGVE------VEIMNALGKAL 259
            |.                   |.|                 |:|.|.|      |:|:..:.:.:
  Fly   381 WTPHGHLNITEPSMFFDAGSMNVTLVVITILETPYVMMHYGKNFTGNERFYGFCVDILETISREV 445

  Fly   260 NFKPVYYKPNQTENMDWTELDGGASVAYGSGNPDGYAQNGTHIDSMLVDEVAAHSARFAIGDLHL 324
            .|..:              ||......||:.:|:....||      :|.::..:.|..|:|.:.:
  Fly   446 GFDYI--------------LDLVPDRKYGAKDPETGEWNG------MVAQLMKYKADLAVGSMTI 490

  Fly   325 FQVYLKLVELSAPH-NFE-CLTFLTPESSTDNSWQTFILPFSAGMWVGVLLSLFVVGTVFYAISF 387
            ......:::.:.|. |.. .:.|..|.|.....: :|:.|.:..:|:.||::.|:|....|.:
  Fly   491 TYARESVIDFTKPFMNLGISILFKVPTSEPTRLF-SFMNPLAIEIWIYVLIAYFLVSLCIYIV-- 552

  Fly   388 LNAIINGNVSSEFFRCLR--PNRNVPMDPKIYRRISFRIAISRYRSSKGDRMPRDLFDGYTNCIL 450
                  |.:|...::|:.  ...|:.:..:.....||...|..:.....|
  Fly   553 ------GKLSPIEWKCINACDLENISIGNQFSLTDSFWFTIGTFMQQSPD--------------- 596

  Fly   451 LTYSMLLYVALPRMPRNWPLRVLTGWYWIYCILLVATYRASFTAILANPAARVTIDTLEDLLR-- 513
                  :|      ||....|:::..:..:.:::||:|.|:..|.|........|:..|||..
  Fly   597 ------IY------PRAMSTRIISSTWGFFSLIIVASYTANLAAFLTTERMINPIENAEDLASQT 649

  Fly   514 --SHIPPSTGATENRQFFLEANDEVARKVGEKME-------VFGYSDDLTSRIAKGQCAYYDNEF 569
              |:....:|:|  ..||.::..|..:|:...|:       ...|.|.: .|:.:|..|:.....
  Fly   650 EISYGTLDSGST--MTFFRDSVIETYKKIWRSMDNKKPSAFTTTYEDGI-KRVNQGNYAFLMEST 711

  Fly   570 YLRYLRVADESGSALHIMKECVLYM--------PVVLAMEKNSALKPRVDASIQHLAEGG----L 622
            .|.|:           :.::|.|..        ...:|..|.|..:.::..:|..|.|.|    |
  Fly   712 MLDYI-----------VQRDCNLTQIGGLLDTKGYGIATPKGSPWRDKISLAILELQERGDIQML 765

  Fly   623 IAKWLKDAIEHLPAEALAQQEAL--MNIQKFWSSFVALLIGYVISMLTLLAERWH-FKHIVMKHP 684
            ..||.|:..|....:..::|...  :.::.....||.|:.|.:::.:....|.|: |::.....|
  Fly   766 YDKWWKNTDETCTRKNTSKQSKANSLGLESIGGVFVVLIAGIIVAAVVAFFEFWYNFRYNYEATP 830

  Fly   685 MYDVYNPSLYYN 696
            ...|.|..  ||
  Fly   831 SQSVVNNK--YN 840

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68a	NP_648455.2	Lig_chan	367..661	CDD:459656	61/320 (19%)
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605	33/138 (24%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	82/438 (19%)
		Lig_chan	532..806	CDD:459656	61/322 (19%)