Protein Alignment Ir68a and Nmdar1

DIOPT Version :9

• Sequence 1: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_730940.1
• Gene: Nmdar1 / 40665
• FlyBaseID: FBgn0010399
• Length: 997
• Species: Drosophila melanogaster
• Alignment Length: 667
• Identity: 121/667 - (18%)
• Similarity: 220/667 - (32%)
• Gaps: 197/667 - (29%)

  Fly   158 HLWSVFIDAIF--------LKRQL-----------DNKYTISTIAFPGILSGVLVMK-------N 196
            |:|.|...|:|        |..||           |:.|.::: |...::|...:.:       :
  Fly   264 HVWIVTEQALFSNNTPDGVLGLQLEHAHSDKGHIRDSVYVLAS-AIKEMISNETIAEAPKDCGDS 327

  Fly   197 IANWELGK------------GLNGRILFADKTSNLFGTSLPVAISE----HV------------- 232
            ..|||.||            |..|::.|.|....::.....:.|.|    ||
  Fly   328 AVNWESGKRLFQYLKSRNITGETGQVAFDDNGDRIYAGYDVINIREQQKKHVVGKFSYDSMRAKM 392

  Fly   233 ------PMVLW-ANATKSFQGVEVEIMNALGKALNFKPVYY-----------KPNQT-----ENM 274
                  ..::| ....:..:|:.:.....| ..:..||..|           :|::.     .|.
  Fly   393 RMRINDSEIIWPGKQRRKPEGIMIPTHLRL-LTIEEKPFVYVRRMGDDEFRCEPDERPCPLFNNS 456

  Fly   275 DWT---------------ELDGGASVAYGSG-NPDG-----YAQNGTHIDSM------LVDEVAA 312
            |.|               ||....:..|... :|||     ..:|.|...::      |:.|:..
  Fly   457 DATANEFCCRGYCIDLLIELSKRINFTYDLALSPDGQFGHYILRNNTGAMTLRKEWTGLIGELVN 521

  Fly   313 HSARFAIGDLHLFQVYLKLVELSAPHNFECLTFLTPESSTDNSWQTFILPFSAGMWVGVLLSLFV 377
            ..|...:..|.:.....:.:|.|.|..::.:|.|..:.|..::..:|:.|||..:|:.|::|:.|
  Fly   522 ERADMIVAPLTINPERAEYIEFSKPFKYQGITILEKKPSRSSTLVSFLQPFSNTLWILVMVSVHV 586

  Fly   378 VGTVFYAISFLNAIINGNVSSEFFRCLRPNRNVPMDPKIYRRISFRIAISRYRSSKGDRMPRDLF 442
            |..|.|.:.                                |.|   ...|::.|..|.......
  Fly   587 VALVLYLLD--------------------------------RFS---PFGRFKLSHSDSNEEKAL 616

  Fly   443 DGYTNCILLTYSMLLYVALPR-MPRNWPLRVLTGWYWI-YCILLVATYRASFTAILANPAARVTI 505
            : .::.:...:.:||...:.. .||::..||| |..|. :.:::||:|.|:..|.|.....:..:
  Fly   617 N-LSSAVWFAWGVLLNSGIGEGTPRSFSARVL-GMVWAGFAMIIVASYTANLAAFLVLERPKTKL 679

  Fly   506 DTLEDL-LRSHIPPSTGAT----------------ENRQFFLEANDEVARKVGEKMEVFGYSDDL 553
            ..:.|. ||:.:...|.||                .|....:|||:            :..::..
  Fly   680 SGINDARLRNTMENLTCATVKGSSVDMYFRRQVELSNMYRTMEANN------------YATAEQA 732

  Fly   554 TSRIAKGQCAYYDNEFYLRYLRVADESGSALHIMKECVLYMPVVL--------AMEKNSALKPRV 610
            ...:.||:...:          :.|.|.......|:|.|.....|        .::|.|.....|
  Fly   733 IQDVKKGKLMAF----------IWDSSRLEYEASKDCELVTAGELFGRSGYGIGLQKGSPWTDAV 787

  Fly   611 DASIQHLAEGGLIAKWLKDAIEH----LPAEALAQQEALMNIQKFWSSFVALLIGYVISMLTLLA 671
            ..:|....|.|.:.|..|..|.|    ...|...:....:.::.....|:.:.:|....:..::.
  Fly   788 TLAILEFHESGFMEKLDKQWIFHGHVQQNCELFEKTPNTLGLKNMAGVFILVGVGIAGGVGLIII 852

  Fly   672 ERWHFKHIVMKHPMYDV 688
            |..:.||.|.|....|:
  Fly   853 EVIYKKHQVKKQKRLDI 869

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68a	NP_648455.2	Lig_chan	429..661	CDD:278489	47/262 (18%)
Nmdar1	NP_730940.1	PBP1_iGluR_NMDA_NR1	12..405	CDD:107374	26/141 (18%)
		ANF_receptor	58..371	CDD:279440	21/107 (20%)
		PBP2_iGluR_NMDA_Nr1	417..818	CDD:270437	85/460 (18%)
		HisJ	451..>558	CDD:223904	20/106 (19%)
		Periplasmic_Binding_Protein_Type_2	<516..651	CDD:304360	33/171 (19%)
		Lig_chan	575..838	CDD:278489	57/321 (18%)
		CaM_bdg_C0	854..882	CDD:287524	5/16 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462725
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840