Protein Alignment Ir68a and GluRIIB

DIOPT Version :10

• Sequence 1: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_523485.3
• Gene: GluRIIB / 33789
• FlyBaseID: FBgn0020429
• Length: 913
• Species: Drosophila melanogaster
• Alignment Length: 572
• Identity: 117/572 - (20%)
• Similarity: 209/572 - (36%)
• Gaps: 143/572 - (25%)

  Fly   158 HLWSVFIDAIFLKRQLDNKYTISTIAFPGILSGVLVMKNIANWELGKGLNGRILFADKTSNLFGT 222
            |:|:.....:..::..:|    ||.|        |..|.:.|.|         .|:.|.     .
  Fly   384 HIWNKEFQLVDFEKLREN----STQA--------LKQKRLQNKE---------DFSQKP-----I 422

  Fly   223 SLPVAISEHVPMVLWA--------NATKSFQGVEVEIMNALGKA----LNFKPVYYKPNQTENMD 275
            ...||.....|...|.        ...:.|:|..|:::..|.:.    .||:||  :.|:
  Fly   423 RYTVATRVGKPYFSWREEPEGVHYEGNERFEGYAVDLIYMLAQECKFDFNFEPV--RDNK----- 480

  Fly   276 WTELDGGASVAYGSGNPDGYAQNGTHIDSMLVDEVAAHSARFAIGDLHLFQVYLKLVELSAPH-- 338
                       |||     |..|....|. ::.::..::|:..|.||.:.|....:|:.:.|.
  Fly   481 -----------YGS-----YDANTDEWDG-IIRQLIDNNAQIGICDLTITQARRSVVDFTVPFMQ 528

  Fly   339 -NFECLTFLTPESSTDNSWQTFILPFSAGMWVGVLLSLFVVGTVFYAISFLNAIINGNVSSEFFR 402
             ....|::..|....|  ...|:.|::|.:|:.|::::.:..   :|:.|...|       :.:.
  Fly   529 LGISILSYKEPPPKAD--IYAFLNPYNAEVWLFVMIAMMITA---FALIFTGRI-------DQYE 581

  Fly   403 CLRPNRNVPMDPKIYRRISFRIAISRYRSSKGDRMPRDLFDGYTNCILLTYSMLLYVALPRMPRN 467
            ..:|..||..:                       |.|......:|.:.|....:|......:||.
  Fly   582 WDQPVENVNRE-----------------------MERQNIWHLSNALWLVLGSMLNQGCDLLPRG 623

  Fly   468 WPLRVLTGWYWIYCILLVATYRASFTAILANPAARVTIDTLEDLL-RSHIPPST---GATENRQF 528
            .|:|:||.::||:.:|:..||.|...|.:.:......|.:|.||: ::.:...|   |||.  .:
  Fly   624 LPMRLLTAFWWIFALLISQTYIAKLAAFITSSKIAGDIGSLHDLVDQNKVQFGTIRGGATS--VY 686

  Fly   529 FLEANDEVARKVGEKMEVFGYSDDLTS---------RIAKGQCAYYDNEFYLRYLRVADESGSAL 584
            |.|:||...|....||..| ..|..|.         :::||..|:......|:|
  Fly   687 FSESNDTDNRMAWNKMLSF-KPDAFTKNNEEGVDRVKLSKGTYAFLMETTNLQY----------- 739

  Fly   585 HIMKECVLYM--------PVVLAMEKNSALKPRVDASIQHLAEGG----LIAKWLKDAIEHLPAE 637
            ::.:.|.|..        ...:|:..|:..:..:...|..|:|.|    |..||.........:.
  Fly   740 YVQRNCELTQIGESFGEKHYGIAVPLNADFRSNLSVGILRLSERGELFKLRNKWFNSNESTCDSN 804

  Fly   638 ALAQQEALMNIQKFWSSFVALLIGYVISMLTLLAE-RWHFKHIVMKH---PM 685
            .....:...::......||.|::|.|:.::..:|| .||.:.|.:|.   ||
  Fly   805 VPTIDDGQFDMDSVGGLFVVLIVGVVVGLVIGVAEFLWHVQRISVKEKIPPM 856

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68a	NP_648455.2	Lig_chan	367..661	CDD:459656	63/318 (20%)
GluRIIB	NP_523485.3	PBP1_iGluR_Kainate	26..387	CDD:380605	1/2 (50%)
		PBP2_iGluR_Kainate	422..795	CDD:270432	92/445 (21%)