Protein Alignment Ir68a and Grik3

DIOPT Version :10

• Sequence 1: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_001106187.1
• Gene: Grik3 / 298521
• RGDID: 71027
• Length: 919
• Species: Rattus norvegicus
• Alignment Length: 536
• Identity: 112/536 - (20%)
• Similarity: 193/536 - (36%)
• Gaps: 152/536 - (28%)

  Fly   194 MKNIANWELGKGLN------GRILFADKTSNLFGTSLPVAISEHVPMVLWANATKS------FQG 246
            ::.:..|....|||      ||  ..:.|.:|...||.|......|.|::..:.::      |:|
  Rat   402 LEKVGVWSPADGLNITEVAKGR--GPNVTDSLTNRSLIVTTLLEEPFVMFRKSDRTLYGNDRFEG 464

  Fly   247 VEVEIMNALGKALNFKPVYYKPNQTENMDWTELDGGASVAYGSGNPDGYAQNGTHIDSMLVDEVA 311
            ..::::..|...|.|.   |:....|       ||    .||:.:..| ..||      :|.|:.
  Rat   465 YCIDLLKELAHILGFS---YEIRLVE-------DG----KYGAQDDKG-QWNG------MVKELI 508

  Fly   312 AHSARFAIGDLHLFQVYLKLVELSAPHNFECLTFLT--------PESSTDNSWQTFILPFSAGMW 368
            .|.|..|:..|.:..|..|.::.|.|       |:|        ..:.|:.|..:|:.|.|..:|
  Rat   509 DHKADLAVAPLTITHVREKAIDFSKP-------FMTLGVSILYRKPNGTNPSVFSFLNPLSPDIW 566

  Fly   369 VGVLLSLFVVGTVFYAISFLNAIINGNVSSEFFRCLRPNRNVPMDPKIYRRISFRIAISRYRSSK 433
            :.|||:...|..|.:.|:                                |.|
  Rat   567 MYVLLAYLGVSCVLFVIA--------------------------------RFS------------ 587

  Fly   434 GDRMPRDLFDGY----------TNCILLT---YSM--LLYVALPRMPRNWPLRVLTGWYWIYCIL 483
                |.:.:|.:          .|..||.   :.|  |:......||:....|::.|.:|.:.::
  Rat   588 ----PYEWYDAHPCNPGSEVVENNFTLLNSFWFGMGSLMQQGSELMPKALSTRIIGGIWWFFTLI 648

  Fly   484 LVATYRASFTAILANPAARVTIDTLEDLLR----SHIPPSTGATENRQFFLEANDEVARKVGEKM 544
            ::::|.|:..|.|........||:.:||.:    .:.....|||  ..||.::      |:....
  Rat   649 IISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVKDGAT--MTFFKKS------KISTFE 705

  Fly   545 EVFGYSDDLTSRIAKGQCAYYDNEFYLRYLRVAD-----ESGSALHI-MKECVLYMPVVLAMEK- 602
            :::.:.....|.:.|      :||..::....||     ||.:..:| .:.|.|.....|...|
  Rat   706 KMWAFMSSKPSALVK------NNEEGIQRTLTADYALLMESTTIEYITQRNCNLTQIGGLIDSKG 764

  Fly   603 -------NSALKPRVDASIQHLAEGGLI----AKWLKDAIEHLPAEALAQQEALMNIQKFWSSFV 656
                   .|..:.::..:|..|.|...:    .||.:.:  ..|.|...:..|| .|||....|:
  Rat   765 YGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWWRGS--GCPEEENKEASAL-GIQKIGGIFI 826

  Fly   657 ALLIGYVISMLTLLAE 672
            .|..|.|:|:|..:.|
  Rat   827 VLAAGLVLSVLVAVGE 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68a	NP_648455.2	Lig_chan	367..661	CDD:459656	63/330 (19%)
Grik3	NP_001106187.1	PBP1_iGluR_Kainate	37..417	CDD:380605	4/14 (29%)
		PBP2_iGluR_Kainate_GluR7	433..801	CDD:270441	90/457 (20%)