Protein Alignment Ir68a and Gria4

DIOPT Version :9

• Sequence 1: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_001106655.1
• Gene: Gria4 / 29629
• RGDID: 61863
• Length: 902
• Species: Rattus norvegicus
• Alignment Length: 822
• Identity: 155/822 - (18%)
• Similarity: 279/822 - (33%)
• Gaps: 258/822 - (31%)

  Fly    15 AMATSIPIPIANPA-PLSG---YEMQLK--------ILLQKILWVANVKRCFAVITD-DLHYPIY 66
            :..:::.|.:..|: |..|   :.:||:        .||....|     .||..:.| |..|.|.
  Rat   108 SFCSALHISLITPSFPTEGESQFVLQLRPSLRGALLSLLDHYEW-----NCFVFLYDTDRGYSIL 167

  Fly    67 DRIFFESVGR---RVIPFFVMRTNE------SDDLQRPSRQVELFVKAIKSSDCEL----NVI-- 116
            ..| .|..|:   .|....|...|:      .::|.|  ||.:.||     .|||:    |::
  Rat   168 QAI-MEKAGQNGWHVSAICVENFNDVSYRQLLEELDR--RQEKKFV-----IDCEIERLQNILEQ 224

  Fly   117 TILNGWQVQRFLGYIYDNRSLNMQ----KKFVLLH--------DLRLFESDMI----HLWSVFID 165
            .:..|..|:   ||.|...:|..:    ::|:  |        .|..|.:.|:    ..|.....
  Rat   225 IVSVGKHVK---GYHYIIANLGFKDISLERFI--HGGANVTGFQLVDFNTPMVTKLMDRWKKLDQ 284

  Fly   166 AIFLKRQLDNKYTISTIAFPGIL---------------------SGVLVMKNIANWELG------ 203
            ..:...:...||| |.:.:.|:|                     :|..:....|.|..|
  Rat   285 REYPGSETPPKYT-SALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANPAAPWGQGIDMERT 348

  Fly   204 ------KGLNGRILF-----------------------------ADK-------------TSNLF 220
                  :||.|.:.|                             .||             |:.:.
  Rat   349 LKQVRIQGLTGNVQFDHYGRRVNYTMDVFELKSTGPRKVGYWNDMDKLVLIQDMPTLGNDTAAIE 413

  Fly   221 GTSLPVAISEHVPMVLWANATKSFQGVE------VEIMNALGKALNFKPVYYK----PNQTENMD 275
            ..::.|......|.|::....:.|:|.:      |::.:.:.|.:..|   ||    |
  Rat   414 NRTVVVTTIMESPYVMYKKNHEMFEGNDKYEGYCVDLASEIAKHIGIK---YKIAIVP------- 468

  Fly   276 WTELDGGASVAYGSGNPDGYAQNGTHIDSMLVDEVAAHSARFAIGDLHLFQVYLKLVELSAPHNF 340
                ||    .||:.:.|....||      :|.|:....|..||..|.:..|..::::.|.|...
  Rat   469 ----DG----KYGARDADTKIWNG------MVGELVYGKAEIAIAPLTITLVREEVIDFSKPFMS 519

  Fly   341 ECLTFL--TPESSTDNSWQTFILPFSAGMWVGVLLSLFVVGTVFYAISFLNAIINGNVSSEFFRC 403
            ..::.:  .|:.|....: :|:.|.:..:|:.::.:...|..|.:.:|             .|..
  Rat   520 LGISIMIKKPQKSKPGVF-SFLDPLAYEIWMCIVFAYIGVSVVLFLVS-------------RFSP 570

  Fly   404 LRPNRNVPMDPKIYRRISFRIAISRYRSSKGDRMPRDLFDGYTNCILLTYSMLLYVALPRMPRNW 468
            ...:...|.|.|               ....|:.|.:.  |..|.:..:....:.......||:.
  Rat   571 YEWHTEEPEDGK---------------EGPSDQPPNEF--GIFNSLWFSLGAFMQQGCDISPRSL 618

  Fly   469 PLRVLTGWYWIYCILLVATYRASFTAILANPAARVTIDTLEDLLR-SHIPPST---GATENRQFF 529
            ..|::.|.:|.:.::::::|.|:..|.|........|::.|||.: :.|...|   |:|  ::||
  Rat   619 SGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGST--KEFF 681

  Fly   530 LEANDEVARKVGEKMEVFGYSDD------------LTSRIAKGQCAYYDNEFYLRYLRV------ 576
              ...::|  |.|||..:..|.:            ...|.:||:.|:........|:..
  Rat   682 --RRSKIA--VYEKMWTYMRSAEPSVFTRTTAEGVARVRKSKGKFAFLLESTMNEYIEQRKPCDT 742

  Fly   577 ------ADESGSALHIMKECVLYMPVVLAMEKNSALKPRVDASIQHLAEGGLI----AKWLKDAI 631
                  .|..|..              :|..|.|:|:..|:.::..|.|.||:    .||..|..
  Rat   743 MKVGGNLDSKGYG--------------VATPKGSSLRNAVNLAVLKLNEQGLLDKLKNKWWYDKG 793

  Fly   632 EHLPAEALAQQE-ALMNIQKFWSSFVALLIGYVISMLTLLAE 672
            |.......::.: :.:::......|..|:.|..::||..|.|
  Rat   794 ECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIE 835

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68a	NP_648455.2	Lig_chan	429..661	CDD:278489	51/264 (19%)
Gria4	NP_001106655.1	PBP1_iGluR_AMPA_GluR4	28..398	CDD:107383	59/308 (19%)
		ANF_receptor	39..380	CDD:279440	57/290 (20%)
		PBP2_iGluR_AMPA_GluR4	414..795	CDD:270445	87/455 (19%)
		Lig_chan	546..825	CDD:278489	59/328 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349796
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740