Protein Alignment Ir68a and Grik1

DIOPT Version :10

• Sequence 1: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_001104587.1
• Gene: Grik1 / 29559
• RGDID: 2732
• Length: 949
• Species: Rattus norvegicus
• Alignment Length: 617
• Identity: 125/617 - (20%)
• Similarity: 211/617 - (34%)
• Gaps: 165/617 - (26%)

  Fly   129 GYIYDNRSLNMQKKFVLLHDLRLFESDMIHLWSVFIDAIFLKRQLDNKYTISTIAFPGILSGVL- 192
            |.|..|::..::|.|.|                   |.|.||.:...|.:       |.:|..|
  Rat   374 GRITFNKTDGLRKDFDL-------------------DIISLKEEGTEKAS-------GEVSKHLY 412

  Fly   193 -VMKNIANWELGKGLNGRILFADKTSN----LFGTSLPVAISEHVPMVLWANATK------SFQG 246
             |.|.|..|....|||......|:::|    |...:|.|......|.|::..:.|      .|:|
  Rat   413 KVWKKIGIWNSNSGLNMTDGNRDRSNNITDSLANRTLIVTTILEEPYVMYRKSDKPLYGNDRFEG 477

  Fly   247 VEVEIMNALGKALNF-KPVYYKPNQTENMDWTELDGGASVAYGSGNPDGYAQNGTHIDSMLVDEV 310
            ..::::..|...|.| ..|...|           ||    .||:.|..| ..||      :|.|:
  Rat   478 YCLDLLKELSNILGFLYDVKLVP-----------DG----KYGAQNDKG-EWNG------MVKEL 520

  Fly   311 AAHSARFAIGDLHLFQVYLKLVELSAPHNFECLTFLT--------PESSTDNSWQTFILPFSAGM 367
            ..|.|..|:..|.:..|..|:::.|.|       |:|        ..:.|:....:|:.|.|..:
  Rat   521 IDHRADLAVAPLTITYVREKVIDFSKP-------FMTLGISILYRKPNGTNPGVFSFLNPLSPDI 578

  Fly   368 WVGVLLSLFVVGTVFYAISFLNAIINGNVSSEFFRCLRPNRNVPMDPKIYRRISFRIAISRYRSS 432
            |:.|||:...|..|.:.|:....          :....|:   |.:|
  Rat   579 WMYVLLACLGVSCVLFVIARFTP----------YEWYNPH---PCNP------------------ 612

  Fly   433 KGDRMPRDLFD-GYT--NCILLTYSMLLYVALPRMPRNWPLRVLTGWYWIYCILLVATYRASFTA 494
                 ..|:.: .:|  |........|:......||:....|::.|.:|.:.::::::|.|:..|
  Rat   613 -----DSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWFFTLIIISSYTANLAA 672

  Fly   495 ILANPAARVTIDTLEDLLR----SHIPPSTGATENRQFFLEANDEVARKVG--EKMEVFGYSDDL 553
            .|........||:.:||.:    .:.....|:|  ..||.::      |:.  |||..| .|...
  Rat   673 FLTVERMESPIDSADDLAKQTKIEYGAVRDGST--MTFFKKS------KISTYEKMWAF-MSSRQ 728

  Fly   554 TSRIAKGQCAYYDNEFYLRYLRVADESGSALHIMKECVLYMPVVLAMEK--------NSALKPRV 610
            .|.:.|.............|..:.:.:.......:.|.|.....|...|        .|..:.::
  Rat   729 QSALVKNSDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKI 793

  Fly   611 DASIQHLAEGGLI----AKWLKDAIEHLPAEALAQQEALMNIQKFWSSFVALLIGYVISMLTLLA 671
            ..:|..|.|.|.:    .||.:.  ...|.|...:..|| .::.....|:.|..|.|:|:...:.
  Rat   794 TIAILQLQEEGKLHMMKEKWWRG--NGCPEEDSKEASAL-GVENIGGIFIVLAAGLVLSVFVAIG 855

  Fly   672 E--------------------RWHFKHIVMKH 683
            |                    |::|::.|..|
  Rat   856 EFLYKSRKNNDVEQKGKSSRLRFYFRNKVRFH 887

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68a	NP_648455.2	Lig_chan	367..661	CDD:459656	57/314 (18%)
Grik1	NP_001104587.1	PBP1_iGluR_Kainate	38..431	CDD:380605	21/82 (26%)
		Periplasmic_Binding_Protein_Type_2	446..815	CDD:473866	87/442 (20%)