Protein Alignment Ir68a and GRIN2C

DIOPT Version :9

• Sequence 1: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: XP_016880033.1
• Gene: GRIN2C / 2905
• HGNCID: 4587
• Length: 1337
• Species: Homo sapiens
• Alignment Length: 604
• Identity: 112/604 - (18%)
• Similarity: 207/604 - (34%)
• Gaps: 158/604 - (26%)

  Fly   191 VLVMKNIANWEL-GKGLNGRILFADKTSNLFGTSL-PVAISEHVPMVLWANAT---KSFQGVEVE 250
            |:.:.....||: |:..:|.:.........:..|| ||..|.|:.:     ||   :.|..||..
Human   435 VIALNRHRLWEMVGRWEHGVLYMKYPVWPRYSASLQPVVDSRHLTV-----ATLEERPFVIVESP 494

  Fly   251 IMNALGKALNFKPVYYKPNQTENMDWTELDGGASVAYGSGNPDGYAQ------------------ 297
            .....|...|..|...:.|.|               :.||:...|.:
Human   495 DPGTGGCVPNTVPCRRQSNHT---------------FSSGDVAPYTKLCCKGFCIDILKKLARVV 544

  Fly   298 ----------NGTH------IDSMLVDEVAAHSARFAIGDLHLFQVYLKLVELSAPHNFECLTFL 346
                      ||.|      :.:.::.||....|..|||.|.:.:...::|:.|.|.....::.:
Human   545 KFSYDLYLVTNGKHGKRVRGVWNGMIGEVYYKRADMAIGSLTINEERSEIVDFSVPFVETGISVM 609

  Fly   347 TPESSTDNSWQTFILPFSAGMWVGVLLSLFVVGTVFYAISFLNAIINGNVSSEFFRCLRPNRNVP 411
            ...|:...|...|:.|:|..:||    .:||:.....||:..        ..|:|..:..|:|
Human   610 VARSNGTVSPSAFLEPYSPAVWV----MMFVMCLTVVAITVF--------MFEYFSPVSYNQN-- 660

  Fly   412 MDPKIYRRISFRIAISRYRSSKGDRMPRDLFDGYT--NCILLTYSMLLYVALP-RMPRNWPLRVL 473
                          ::|.:.|.|        ..:|  ..:.|.::::...::| ..||....:::
Human   661 --------------LTRGKKSGG--------PAFTIGKSVWLLWALVFNNSVPIENPRGTTSKIM 703

  Fly   474 TGWYWIYCILLVATYRASFTAILANPAARVTIDTLEDLLRSHI---------------------- 516
            ...:..:.::.:|:|.|:..|.:.......|:..|.|....|:
Human   704 VLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKKSLHLENTGVAWTAFKTFCSDYFQRPQ 768

  Fly   517 ---PP------STGATEN--RQFFLEANDEVARKVGEKMEVFGYSDDLTS--------RIAKGQC 562
               ||      ..|:||.  |..:.:.:..:.:.....:|     |.|||        .:.:...
Human   769 DQYPPFRFGTVPNGSTERNIRSNYRDMHTHMVKFNQRSVE-----DALTSLKMGSEAQPVPRKLD 828

  Fly   563 AYYDNEFYLRYLRVADESGSALHIMKECVLYMP-VVLAMEKNSALKPRVD-ASIQHLAEG---GL 622
            |:..:...|.|:...||....:.|....|.... ..:||:|:|..|..:| |.:|.|.:|   .|
Human   829 AFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIAMQKDSHWKRAIDLALLQFLGDGETQKL 893

  Fly   623 IAKWLKDAIEHLPAEALAQQEALMNIQKFWSSFVALLIGYVISMLTLLAER---WHFKHIVMKHP 684
            ...||....::...|.::.:   ::|......|..||:...:::|....|.   |..:|.|....
Human   894 ETVWLSGICQNEKNEVMSSK---LDIDNMAGVFYMLLVAMGLALLVFAWEHLVYWKLRHSVPNSS 955

  Fly   685 MYD---VYNPSLYYNFKRI 700
            ..|   .::..:|..|..:
Human   956 QLDFLLAFSRGIYSCFSGV 974

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68a	NP_648455.2	Lig_chan	429..661	CDD:278489	51/280 (18%)
GRIN2C	XP_016880033.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165155888
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740