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Protein Alignment Ir68a and GRIA3

DIOPT Version :9

Sequence 1:	NP_648455.2	Gene:	Ir68a / 39269	FlyBaseID:	FBgn0036150	Length:	704	Species:	Drosophila melanogaster
Sequence 2:	NP_000819.4	Gene:	GRIA3 / 2892	HGNCID:	4573	Length:	894	Species:	Homo sapiens

Alignment Length:	496	Identity:	101/496 - (20%)
Similarity:	190/496 - (38%)	Gaps:	103/496 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 DKTSNLFGTSLPVAISEHVPMVLWANATKSFQGVE------VEIMNALGKALNFKPVYYKPNQTE 272
            |..|:...|.:...|.|. |.|::....:..:|.|      |::...:.|.:..|   ||.:...
Human   416 DSASSENRTIVVTTILES-PYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIK---YKLSIVG 476

  Fly   273 NMDWTELDGGASVAYGSGNPDGYAQNGTHIDSMLVDEVAAHSARFAIGDLHLFQVYLKLVELSAP 337
                   ||    .||:.:|:....||      :|.|:....|..|:..|.:..|..::::.|.|
Human   477 -------DG----KYGARDPETKIWNG------MVGELVYGRADIAVAPLTITLVREEVIDFSKP 524

  Fly   338 HNFECLTFL--TPESSTDNSWQTFILPFSAGMWVGVLLSLFVVGTVFYAISFLNAIINGNVSSEF 400
            .....::.:  .|:.|....: :|:.|.:..:|:.::.:...|..|.:.:|..         |.:
Human   525 FMSLGISIMIKKPQKSKPGVF-SFLDPLAYEIWMCIVFAYIGVSVVLFLVSRF---------SPY 579

  Fly   401 FRCLRPNRNVPMDPKIYRRISFRIAISRYRSSKGDRMPRDLFDGYTNCILLTYSMLLYVALPRMP 465
            ...|..|...|.||:                |..|  |.:.| |..|.:..:....:.......|
Human   580 EWHLEDNNEEPRDPQ----------------SPPD--PPNEF-GIFNSLWFSLGAFMQQGCDISP 625

  Fly   466 RNWPLRVLTGWYWIYCILLVATYRASFTAILANPAARVTIDTLEDLLR-SHIPPST---GATENR 526
            |:...|::.|.:|.:.::::::|.|:..|.|........|::.|||.: :.|...|   |:|  :
Human   626 RSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGST--K 688

  Fly   527 QFFLEANDEVARKVGEKME-----VFGYSD-DLTSRI--AKGQCAYYDNEFYLRYLRV------- 576
            :||..:...|..|:...|:     ||..:. |..:|:  :||:.|:........|:..
Human   689 EFFRRSKIAVYEKMWSYMKSAEPSVFTKTTADGVARVRKSKGKFAFLLESTMNEYIEQRKPCDTM 753

  Fly   577 -----ADESGSALHIMKECVLYMPVVLAMEKNSALKPRVDASIQHLAEGGLI----AKWLKDAIE 632
                 .|..|..              :|..|.|||:..|:.::..|.|.||:    .||..|..|
Human   754 KVGGNLDSKGYG--------------VATPKGSALRNAVNLAVLKLNEQGLLDKLKNKWWYDKGE 804

  Fly   633 HLPAEALAQQE-ALMNIQKFWSSFVALLIGYVISMLTLLAE 672
            .......::.: :.:::......|..|:.|..::|:..|.|
Human   805 CGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMMVALIE 845

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.