Protein Alignment Ir68a and Grin2d

DIOPT Version :9

• Sequence 1: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: XP_038951440.1
• Gene: Grin2d / 24412
• RGDID: 2740
• Length: 1334
• Species: Rattus norvegicus
• Alignment Length: 695
• Identity: 129/695 - (18%)
• Similarity: 234/695 - (33%)
• Gaps: 210/695 - (30%)

  Fly    81 FFVMRTNESDDLQRPSRQVELFVKAIKSSDCELNVITILNGWQ-VQRFLGYI----YDNRSLNMQ 140
            |.|......|||   :|:|            ...|..:..|.| :.|..|::    :|.|:.|
  Rat   302 FAVRSAGWRDDL---ARRV------------AAGVAVVARGAQALLRDYGFLPELGHDCRTQN-- 349

  Fly   141 KKFVLLHDLRLFESDMIHLWSVFIDAIFLKRQLDNK-YTISTIAF---PGILSGVLVMKNIANWE 201
                     |....:.:|.:       |:....||: |:.:...|   |.::  |:.:.....||
  Rat   350 ---------RTHRGESLHRY-------FMNITWDNRDYSFNEDGFLVNPSLV--VISLTRDRTWE 396

  Fly   202 LGKGLN--------------GRILF-ADKTSNLFGTSL------------PVA---ISEHVPMVL 236
            :.....              ||.|. .|.|.:|...:|            |::   |.:.||...
  Rat   397 VVGSWEQQTLRLKYPLWSRYGRFLQPVDDTQHLTVATLEERPFVIVEPADPISGTCIRDSVPCRS 461

  Fly   237 WANATKS------------FQGVEVEIMNALGKALNFK-PVYYKPNQTENMDWTELDGGASVAYG 288
            ..|.|.|            .:|..::|:..|...:.|. .:|...|
  Rat   462 QLNRTHSPPPDAPRPEKRCCKGFCIDILKRLAHTIGFSYDLYLVTN------------------- 507

  Fly   289 SGNPDGYAQNGTHIDSM---LVDEVAAHSARFAIGDLHLFQVYLKLVELS--------------- 335
                   .::|..||.:   ::.||....|..|||.|.:.:...::|:.|
  Rat   508 -------GKHGKKIDGVWNGMIGEVFYQRADMAIGSLTINEERSEIVDFSVPFVETGISVMVARS 565

  Fly   336 ----APHNFECLTFLTPESSTDNSWQTFILPFSAGMWVGV-LLSLFVVGTVFYAISFLNAI-ING 394
                :|..|....:|||..|.:        |:|..:||.: ::.|.||....:...:|:.: .|.
  Rat   566 NGTVSPSAFLAFAWLTPPMSPE--------PYSPAVWVMMFVMCLTVVAVTVFIFEYLSPVGYNR 622

  Fly   395 NVSSEFFRCLRPNRNVPMDPKIYRRISFRIAISRYRSSKGDRMPRDLFDGYTNCILLTYSMLLYV 459
            ::::.    .||..:           :|.|..|                     |.|.::::...
  Rat   623 SLATG----KRPGGS-----------TFTIGKS---------------------IWLLWALVFNN 651

  Fly   460 ALP-RMPRNWPLRVLTGWYWIYCILLVATYRASFTAILANPAARVTIDTLEDLL----RSHIPP- 518
            ::| ..||....:::...:..:.::.:|:|.|:..|.:.......|:..|.|..    :...||
  Rat   652 SVPVENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEEYVDTVSGLSDRKFQRPQEQYPPL 716

  Fly   519 -----STGATEN--RQFFLEANDEVARKVGEKMEVFGYSDDLTSRIAKGQCAYYDNEFYLRYLRV 576
                 ..|:||.  |..:.:.:..:.|....::|     :.||...|....|:..:...|.|:..
  Rat   717 KFGTVPNGSTEKNIRSNYPDMHSYMVRYNQPRVE-----EALTQLKAGKLDAFIYDAAVLNYMAR 776

  Fly   577 ADESGSALHIMKECVLYMP-VVLAMEKNSALKPRVD-ASIQHLAEGG---LIAKWLKDAIEHLPA 636
            .||....:.|....|.... ..:|:.|.|..|..:| |.:|.|.:..   |...||.....:...
  Rat   777 KDEGCKLVTIGSGKVFATTGYGIALHKGSRWKRPIDLALLQFLGDDEIEMLERLWLSGICHNDKI 841

  Fly   637 EALAQQEALMNIQKFWSSFVALLIGYVISMLTLLAER---WHFKH 678
            |.::.:   ::|......|..||:...:|:|....|.   |..:|
  Rat   842 EVMSSK---LDIDNMAGVFYMLLVAMGLSLLVFAWEHLVYWRLRH 883

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68a	NP_648455.2	Lig_chan	429..661	CDD:278489	46/249 (18%)
Grin2d	XP_038951440.1	PBP1_iGluR_NMDA_NR2	46..410	CDD:380601	26/142 (18%)
		PBP2_iGluR_NMDA_Nr2	427..838	CDD:270436	88/485 (18%)
		PHA03307	<1125..>1312	CDD:223039

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349795
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830