Protein Alignment Ir68a and Grin2c

DIOPT Version :9

• Sequence 1: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_036707.3
• Gene: Grin2c / 24411
• RGDID: 2739
• Length: 1250
• Species: Rattus norvegicus
• Alignment Length: 587
• Identity: 111/587 - (18%)
• Similarity: 201/587 - (34%)
• Gaps: 153/587 - (26%)

  Fly   191 VLVMKNIANWEL-GKGLNGRILFADKTSNLFGTSL-PVAISEH---------------------- 231
            |:.:.....||: |:..:|.:.........:.||| ||..|.|
  Rat   373 VIALNRHRLWEMVGRWDHGVLYMKYPVWPRYSTSLQPVVDSRHLTVATLEERPFVIVESPDPGTG 437

  Fly   232 ------VPMVLWANATKS-----------FQGVEVEIMNALGKALNFKPVYYKPNQTENMDWTEL 279
                  ||....:|.|.|           .:|..::|:..|.|.:.|....|
  Rat   438 GCVPNTVPCRRQSNHTFSSGDLTPYTKLCCKGFCIDILKKLAKVVKFSYDLY------------- 489

  Fly   280 DGGASVAYGSGNPDGYAQNGTH------IDSMLVDEVAAHSARFAIGDLHLFQVYLKLVELSAPH 338
                           ...||.|      :.:.::.||....|..|||.|.:.:...::::.|.|.
  Rat   490 ---------------LVTNGKHGKRVRGVWNGMIGEVYYKRADMAIGSLTINEERSEIIDFSVPF 539

  Fly   339 NFECLTFLTPESSTDNSWQTFILPFSAGMWVGVLLSLFVVGTVFYAISFLNAIINGNVSSEFFRC 403
            ....::.:...|:...|...|:.|:|..:||    .:||:.....||:..        ..|:|..
  Rat   540 VETGISVMVSRSNGTVSPSAFLEPYSPAVWV----MMFVMCLTVVAITVF--------MFEYFSP 592

  Fly   404 LRPNRNV-----PMDPKIYRRISFRIAISRYRSSKGDRMPRDLFDGYTNCILLTYSMLLYVALP- 462
            :..|:|:     |..|      ||.|..|                     :.|.::::...::|
  Rat   593 VSYNQNLTKGKKPGGP------SFTIGKS---------------------VWLLWALVFNNSVPI 630

  Fly   463 RMPRNWPLRVLTGWYWIYCILLVATYRASFTAILANPAARVTIDTLEDLL----RSHIPP----- 518
            ..||....:::...:..:.::.:|:|.|:..|.:.......|:..|.|..    :...||
  Rat   631 ENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKKFQRPQDQYPPFRFGT 695

  Fly   519 -STGATEN--RQFFLEANDEVARKVGEKMEVFGYSDDLTS-RIAKGQCAYYDNEFYLRYLRVADE 579
             ..|:||.  |..:.:.:..:.:.....:|     |.||| ::.|.....|| ...|.|:...||
  Rat   696 VPNGSTERNIRSNYRDMHTHMVKFNQRSVE-----DALTSLKMGKLDAFIYD-AAVLNYMAGKDE 754

  Fly   580 SGSALHIMKECVLYMP-VVLAMEKNSALKPRVDASIQHLAEGGLIAK----WLKDAIEHLPAEAL 639
            ....:.|....|.... ..:||:|:|..|..:|.::..|...|...|    ||....::...|.:
  Rat   755 GCKLVTIGSGKVFATTGYGIAMQKDSHWKRAIDLALLQLLGDGETQKLETVWLSGICQNEKNEVM 819

  Fly   640 AQQEALMNIQKFWSSFVALLIGYVISMLTLLAER---WHFKHIVMKHPMYD---VYNPSLYYNFK 698
            :.:   ::|......|..||:...:::|....|.   |..:|.|......|   .::..:|..|.
  Rat   820 SSK---LDIDNMAGVFYMLLVAMGLALLVFAWEHLVYWKLRHSVPNSSQLDFLLAFSRGIYSCFN 881

  Fly   699 RI 700
            .:
  Rat   882 GV 883

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68a	NP_648455.2	Lig_chan	429..661	CDD:278489	47/250 (19%)
Grin2c	NP_036707.3	PBP1_iGluR_NMDA_NR2	41..397	CDD:380601	5/23 (22%)
		PBP2_iGluR_NMDA_Nr2	413..813	CDD:270436	88/472 (19%)
		NMDAR2_C	850..>925	CDD:402274	6/34 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349799
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830