Protein Alignment Ir68a and Grik5

DIOPT Version :9

• Sequence 1: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: XP_006228444.1
• Gene: Grik5 / 24407
• RGDID: 2735
• Length: 980
• Species: Rattus norvegicus
• Alignment Length: 642
• Identity: 124/642 - (19%)
• Similarity: 222/642 - (34%)
• Gaps: 205/642 - (31%)

  Fly    66 YD----RIFFESVGRRVIPFFVMRTNESDDLQRPSRQVELFVKAIKSSDCELNVITILNGWQVQR 126
            ||    |:.|.|.|:        |||.:..:...||                         |..|
  Rat   355 YDGLTGRVEFNSKGQ--------RTNYTLRILEKSR-------------------------QGHR 386

  Fly   127 FLGYIYDNRSLNMQKKFVLLHDLRLFESDMIHLWSVFIDAIFLKRQLDNKYTISTIAFPGILSGV 191
            .:|..|.||:|.|.                    :..:| |.|.:.|.||    |:....||...
  Rat   387 EIGVWYSNRTLAMN--------------------ATTLD-INLSQTLANK----TLVVTTILENP 426

  Fly   192 LVMKNIANWELGKGLNGRILFADKTSNLFGTSLPVAISEHVPMVLWANATKSFQGVEVEIMNALG 256
            .||:. .|::   .|:|                                .:.|:|..|:::..|.
  Rat   427 YVMRR-PNFQ---ALSG--------------------------------NERFEGFCVDMLRELA 455

  Fly   257 KALNFKPVYYKPNQTENMDWTELDGGASVAYGSGNPDGYAQNGTHIDSMLVDEVAAHSARFAIGD 321
            :.|.|:   |:....|       ||    .||:..|:| :..|     |:.:.:....|..|:..
  Rat   456 ELLRFR---YRLRLVE-------DG----LYGAPEPNG-SWTG-----MVGELINRQKADLAVAA 500

  Fly   322 LHLFQVYLKLVELSAPHNFECLTFLT--------PESSTDNSWQTFILPFSAGMWVGVLLSLFVV 378
            ..:.....|:::.|.|       |:|        ........:.:|:.|||..:|:.:||:...|
  Rat   501 FTITAEREKVIDFSKP-------FMTLGISILYRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAV 558

  Fly   379 GTVFYAISFLNAIINGNVSSEFFR---CLRPNRNVPMDPKIYRRISFRIAISRYRSSKGDRMPRD 440
            ..|.:..:.|:..       |::.   |||..                              |..
  Rat   559 SCVLFLAARLSPY-------EWYNPHPCLRAR------------------------------PHI 586

  Fly   441 LFDGYT--NCILLTYSMLLYVALPRMPRNWPLRVLTGWYWIYCILLVATYRASFTAILANPAARV 503
            |.:.||  |.:.......:......|||....|.::|.:|.:.::::::|.|:..|.|......|
  Rat   587 LENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEV 651

  Fly   504 TIDTLEDLL-RSHIPPST---GATENRQFFLEANDEVARKVGEKME-----VFGYS-DDLTSRIA 558
            .:::.:||. :::|...|   |:|  ..||..:..:..:::...|:     ||..| ::..:|:.
  Rat   652 PVESADDLADQTNIEYGTIHAGST--MTFFQNSRYQTYQRMWNYMQSKQPSVFVKSTEEGIARVL 714

  Fly   559 KGQCAYY----DNEFYLRYLRVADESGSALHIMKECVLYMPVVLAMEKNSALKPRVDASIQHLAE 619
            ..:.|:.    .||::.|......:.|..|. .|...:.||:      .|..:..:..:|..|.|
  Rat   715 NSRYAFLLESTMNEYHRRLNCNLTQIGGLLD-TKGYGIGMPL------GSPFRDEITLAILQLQE 772

  Fly   620 GG----LIAKWLKDAIEHLPAEALAQQEALMNIQKFWSSFVALLIGYVISMLTLLAE 672
            ..    |..||.:..  ..|.|...:.:.| .::.....||.|:.|.:|::...:.|
  Rat   773 NNRLEILKRKWWEGG--RCPKEEDHRAKGL-GMENIGGIFVVLICGLIIAVFVAVME 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68a	NP_648455.2	Lig_chan	429..661	CDD:278489	51/251 (20%)
Grik5	XP_006228444.1	PBP1_iGluR_Kainate_KA1_2	23..401	CDD:380616	19/98 (19%)
		Periplasmic_Binding_Protein_Type_2	414..785	CDD:389745	92/483 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349802
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740