Protein Alignment Ir68a and glr-8

DIOPT Version :10

• Sequence 1: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_001368711.1
• Gene: glr-8 / 180924
• WormBaseID: WBGene00001619
• Length: 547
• Species: Caenorhabditis elegans
• Alignment Length: 561
• Identity: 105/561 - (18%)
• Similarity: 199/561 - (35%)
• Gaps: 140/561 - (24%)

  Fly   180 STIAFPGILSGVLVMKNIANWELGKGLNGRILFADKTS--NLFGTSLPVAISEHV---------- 232
            :|.|.|   :.:..:.||.     :.:|.::....:||  :.:|.:..::..:|.
 Worm     8 NTTADP---NSIRTLNNIL-----ESINEKVAHPPQTSLTSDYGDAYTLSNEKHFSLSEMKGRTL 64

  Fly   233 ---------PMVLWAN------ATKSF-QGVEVEIMNALGKALNFKPVYYKPNQTENMDWTE-LD 280
                     |.|.:.|      ..|.: .||.:||:..:||.||   :.|:........|.| |:
 Worm    65 KMVVPAIEPPYVNYVNFSDAAVTDKGYGPGVVMEILKEIGKRLN---LTYEILPALGSTWGEYLN 126

  Fly   281 GGASVAYGS---GNPDGYAQNGTHIDSMLVDEVAAHSARFAIGDLHLFQVYLKLVELSAPHNFE- 341
            |..:.|:|.   |..|           :|.........|..|.|            |:.|..||
 Worm   127 GSWTGAFGQLVRGEVD-----------LLAGGAIMEYDRSVIAD------------LTYPFQFEP 168

  Fly   342 -CLTFLTPESSTDNSWQTFILPFSAGMWVGVLLSLFVVGTVFYAISFLNAIINGNVSSEFFRCLR 405
             .:...:||...|::......|||..:||.....:.:.|.:|..::
 Worm   169 TGIMIRSPEKYEDDTLLIVTEPFSWEVWVITAAVILISGVIFLVMT------------------- 214

  Fly   406 PNRNVPMDPKIYRRISFRIAISRYRSSKGDRMPRDLFDGYTNCILLTYSMLLYVALPRMPRNWPL 470
                     .|.|::...:.::.:.|                 |.:.:|:.:...||..||:|..
 Worm   215 ---------NIIRKVYEEMTVTPFES-----------------IWVFFSIFVQQGLPEQPRSWSC 253

  Fly   471 RVLTGWYWIYCILLVATYRASFTAILANPAARVTIDTLEDLLR------SHIPPSTGATENRQFF 529
            |||...:|:..|.|.||:..|..|:.|.....|....::.|:|      ..|.....:....:..
 Worm   254 RVLVALWWLASITLSATFTGSLVALFAVDKTNVPFQNIDQLVRLVKQGKFEIVMDENSFTRTEMI 318

  Fly   530 LEANDEVARKVGEKMEVFGYSDDLTSRIAKGQCAYYDNEFYLRYLRVADESGSALHIMKEC--VL 592
            ..:...|.|.:..:| :..:.....:.||:|......|..|.....:|..:   .:...:|  :|
 Worm   319 ARSKLPVYRDLWHEM-IVNHKVKYVNGIARGVAFVRANPGYALLGPMATLN---FYAYSDCKVIL 379

  Fly   593 Y----MPVVLA--MEKNSALKPRVDASIQHLAEGGLIAKWLKDAIEHLPAEALAQ-------QEA 644
            :    :||.|:  :.|||...|.....|:.:.|.|...||:.|...::..:.:.:       .::
 Worm   380 FNDGILPVYLSIPLVKNSIYSPYFSTKIREMVERGFTQKWIADYRSYVAMQKINECNSTTIGPKS 444

  Fly   645 LMNIQKFWSSFVALLIGYVISMLTLLAE--RWHFKHIVMKH 683
            .:::::...:|...|.|..:.:...:.|  ...|:..:.||
 Worm   445 YLDLKRAQGAFWVFLGGAGLGLALFVGEFIFKFFREKMTKH 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68a	NP_648455.2	Lig_chan	367..661	CDD:459656	55/314 (18%)
glr-8	NP_001368711.1	PBP2_iGluR_ligand_binding	62..424	CDD:270219	88/436 (20%)