Protein Alignment Ir68a and glr-3

DIOPT Version :9

• Sequence 1: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_492017.3
• Gene: glr-3 / 172449
• WormBaseID: WBGene00001614
• Length: 836
• Species: Caenorhabditis elegans
• Alignment Length: 714
• Identity: 140/714 - (19%)
• Similarity: 250/714 - (35%)
• Gaps: 184/714 - (25%)

  Fly    30 LSGYEMQLKILLQKIL----WVANVKRCFAVITDDLHYPIYDRIFFESVGRRVIPFFVMRTNESD 90
            |..|.:.:.|.|||.|    ..||:..|..:    .||.:.|.
 Worm   202 LDRYRIVINIPLQKALHFLEQAANMSMCGVL----YHYVVMDM---------------------- 240

  Fly    91 DLQRPSRQVELFVKAIKS-SDCELNVITI--LNGWQVQRFLGYIYDNRSLNMQKK------FVLL 146
            ||      |.:.:.:|:. .||.:....:  :|...::.....|....|:.:.||      .:.:
 Worm   241 DL------VTVDIDSIRGIEDCNITSFGVHDVNSEYIEDIRQEIVHKSSIRLPKKGVPYTTSIWI 299

  Fly   147 HDLRLFESDM--IHLW-------SVFIDAIFLKRQLDN------------------KYTI----S 180
            ..|||....|  |.:|       |....:...||..:|                  .||:    .
 Worm   300 DTLRLLIRSMKSIQIWDEPRCGSSWKSGSDIKKRFFENPLAGISGDLHWAPSGERSNYTLHVYRR 364

  Fly   181 TIAFPGILSGVLVMKNIANWELGKGLNGRILFADKTSNLF--GTSLPVAISEHVPMVLWANATKS 243
            |::|..........:.||:.|       .::.|:.:..|.  |..|.:::....|.|: ..:..|
 Worm   365 TLSFQKFAEWSSRTRRIASSE-------AVVIANSSEKLTLEGKHLKISVYLEAPFVM-ITSNGS 421

  Fly   244 FQGVEVEIMNALGKALNFKPVYYKPNQTENMDWTELDGGASVAYGSGNPDGYAQNGTHIDSMLVD 308
            ::|..:::::.:...|.|.....|....              ||||...:|..       |.:|.
 Worm   422 YEGYCIDLLHKIANILKFTYTIQKVRDN--------------AYGSKESNGKW-------SGMVG 465

  Fly   309 EVAAHSARFAIGDLHLFQVYLKLVELSAP--HNFECLTFLTPESSTDNSWQTFILPFSAGMWVGV 371
            |:....|..|:..|.:.....::::.:.|  |....:.|..|. ..|:.|..|:.|.|..:|:..
 Worm   466 ELQRGDADLAVASLTISYGRSEVIDFTVPYMHLGISILFKKPR-IRDSDWFKFMDPLSTQVWIMT 529

  Fly   372 LLSLFVVGTVFYAISFLNAIINGNVSSEFFRCLRPNRNVPMDPKIYRRISFRIAISRYRSSKGDR 436
            ..|.|||....:.|:.::..      .:|.|.....:..|:|.:...|.||
 Worm   530 FASYFVVSVAIWIIAKISPY------EQFERDEDNGQYKPVDNQFSLRNSF-------------- 574

  Fly   437 MPRDLFDGYTNCILLTYSMLLYVALPRMPRNWPLRVLTGWYWIYCILLVATYRASFTAILANPAA 501
                   .:|.|.|:.....|      .||....|:|||.:|.:.::|:::|.|:..|:|.....
 Worm   575 -------WFTVCSLMQQGSEL------CPRAASTRLLTGIWWFFALILISSYTANLAAVLTTRRM 626

  Fly   502 RVTIDTLEDL-LRSHIPPST-GATENRQFFLEANDEVARKVGEKME----VFGYSD-DLTSRIAK 559
            ...|:..:|| .::.|...| |......||.|:..|...::.:.|.    :|..|. :..:|:..
 Worm   627 ETPIENADDLAAQTKIKYGTLGRGSTMSFFNESKIETYERMWQLMSSSPGLFVQSSKEGIARVKS 691

  Fly   560 GQCAYYDNEFYLRYLRVADESGSALHIMKECVLYMPV---------VLAMEKNSALKPRVDASIQ 615
            ...||......|.|.           :.::|.| |.:         .:.:.|.|..:..:..:|.
 Worm   692 SDYAYLMESSMLEYA-----------VERDCEL-MQIGGLIDQKGYGIGLPKGSPYRELISTAIL 744

  Fly   616 HLAE----GGLIAKWLKD---AIEHLPAEALAQQEALMNIQKFWSSFVALLIGYVISMLTLLAE 672
            .|.|    ..|..||.||   ..|....:.....|::..|      |:.|::|.|::.:.::.|
 Worm   745 RLQEKTELTELKEKWWKDKSVVCEQPKRKDQDDGESIGGI------FIILVVGLVLTAVLVIFE 802

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68a	NP_648455.2	Lig_chan	429..661	CDD:278489	52/254 (20%)
glr-3	NP_492017.3	PBP1_iGluR_non_NMDA-like	21..385	CDD:380591	40/214 (19%)
		Periplasmic_Binding_Protein_Type_2	401..761	CDD:419667	86/427 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810