Protein Alignment Ir68a and Grin3b

DIOPT Version :9

• Sequence 1: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_579842.2
• Gene: Grin3b / 170796
• RGDID: 621705
• Length: 1002
• Species: Rattus norvegicus
• Alignment Length: 444
• Identity: 94/444 - (21%)
• Similarity: 147/444 - (33%)
• Gaps: 130/444 - (29%)

  Fly   306 LVDEVAAHSARFAIGDLHLFQVYLKLVELSAPHNFECLTFLTPESSTDNSWQTFILPFSAGMWVG 370
            ||.::.|..|..|:....:.....::|:.::|.....|..:.....|.:....|:.|....||||
  Rat   516 LVGDLLAGRAHMAVTSFSINSARSQVVDFTSPFFSTSLGIMVRTRDTASPIGAFMWPLHWSMWVG 580

  Fly   371 V-----LLSLFVV-----------------GTVFYAISFLNAIINGNVSSEFFRCLRPNRNVPMD 413
            |     |.:||:.                 ||||...|.||
  Rat   581 VFAALHLTALFLTLYEWRSPYGLTPRGRNRGTVFSYSSALN------------------------ 621

  Fly   414 PKIYRRISFRIAISRYRSSKGDRMPRDLFDGYTNCILLTYSMLLYVALPRMPRNWPLRVLTGWYW 478
                  :.:.|...|..|||                           .|:.|..   |.|...:.
  Rat   622 ------LCYAILFGRTVSSK---------------------------TPKCPTG---RFLMNLWA 650

  Fly   479 IYCILLVATYRASFTAILANPAARVTIDTLEDLLRSHIP----PSTGA------TENRQFFLEAN 533
            |:|:|::::|.|:..|::      |...|.|:|...|.|    ||.|.      ..:.:.:::|:
  Rat   651 IFCLLVLSSYTANLAAVM------VGDKTFEELSGIHDPKLHHPSQGFRFGTVWESSAEAYIKAS 709

  Fly   534 -DEV---ARKVGEKMEVFGYSDDLTSRIAKGQCAYYDNEFYLRYLRVADESGSALHIMKECVL-- 592
             .|:   .|:........|.: .|||...|.. |:..::..|.|....|.....|.:.|...:
  Rat   710 FPEMHAHMRRHSAPTTPHGVA-MLTSDPPKLN-AFIMDKSLLDYEVSIDADCKLLTVGKPFAIEG 772

  Fly   593 YMPVVLAMEKNSALKPRVDASIQHLAEGGLI----AKWLKDAIEHLPA--EALAQQEAL-MNIQK 650
            |   .:.:.:||.|...:...|......|.|    .||.|    .:|.  ...|..|.| |.:..
  Rat   773 Y---GIGLPQNSPLTSNLSEFISRYKSSGFIDLLHDKWYK----MVPCGKRVFAVTETLQMGVYH 830

  Fly   651 FWSSFVALLIGYVISMLTLLAERWHFKHIVMKHPMYDVYNPSLYYNFKRIYPQH 704
            |...||.|.:|...::||.|.|          |..|.:..|.:....|..|..|
  Rat   831 FSGLFVLLCLGLGSALLTSLGE----------HVFYRLVLPRIRRGNKLQYWLH 874

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68a	NP_648455.2	Lig_chan	429..661	CDD:278489	55/254 (22%)
Grin3b	NP_579842.2	PBP1_iGluR_NMDA_NR3	21..405	CDD:107372
		PBP2_iGluR_NMDA_Nr3	414..808	CDD:270438	72/362 (20%)
		Lig_chan	576..842	CDD:278489	72/340 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	882..910
		Involved in the trafficking and surface expression of NMDARs. /evidence=ECO:0000250	951..984

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166349798
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930