Protein Alignment Ir68a and gria3a

DIOPT Version :10

• Sequence 1: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: XP_073805840.1
• Gene: gria3a / 170452
• ZFINID: ZDB-GENE-020125-5
• Length: 940
• Species: Danio rerio
• Alignment Length: 768
• Identity: 150/768 - (19%)
• Similarity: 270/768 - (35%)
• Gaps: 206/768 - (26%)

  Fly    42 QKILWVANVKRCFAVITDDLHYPIYD--RIFFESVGRRVIPFFVMRTNESDDLQRPSRQVELFVK 104
            :|.:::.:..|.|:::...:...:.:  ::...|||..|.|....|..|..|    .||.:.|:
Zfish   152 EKFVYLYDTDRGFSILQAIMESAVMNNWQVTARSVGNIVDPLEYRRIIEEMD----RRQEKRFL- 211

  Fly   105 AIKSSDCELNVI-TILNGWQV----QRFLGYIYDNRSL---NMQKKFVLLHDLRLFESDMIHLWS 161
                .|||:..| :||.  ||    :...||.|...:|   ||....|......:....:|:..|
Zfish   212 ----IDCEVERINSILE--QVVIAGKNSRGYHYILANLGFTNMSLDKVFSGGANITGFQIINPDS 270

  Fly   162 VFIDAIFLKR--QLDN-----------KYTISTIAFPGIL---------------------SGVL 192
            ..:.. ||:|  :||.           ||| |.:....||                     :|..
Zfish   271 PIVQQ-FLQRWERLDEREFPESRSSPLKYT-SALTHDAILVIAEAFRYLRRQRVDISRRGSAGDC 333

  Fly   193 VMKNIANWELG------------KGLNGRILFADKTSNLFG--TSLPVAISEHVP-----MVLWA 238
            :......|..|            :|:.|.|.|     :.||  ::..|.:.|..|     :..|.
Zfish   334 LANPAVPWSQGIDIERALKMVQVQGMTGNIQF-----DSFGRRSNYTVDVYEMKPGGARKIGYWN 393

  Fly   239 NATKSFQGVEVEIMNALGKALN----------FKPVYYKPN--QTENMDWTE---LDGGASVA-- 286
            ...|....||.::.|......|          ...|.||.|  |.|..|..|   :|..:.:|
Zfish   394 EFEKFVYIVEQQVTNESSSVENRTIVVTTIMEAPYVMYKRNYMQLEGNDRYEGYCVDLASEIAKH 458

  Fly   287 --------------YGSGNPDGYAQNGTHIDSMLVDEVAAHSARFAIGDLHLFQVYLKLVELSAP 337
                          ||:.:|:....||      :|.|:....|..|:..|.:..|..::::.|.|
Zfish   459 VGIKYKLSIVADGKYGARDPETKTWNG------MVGELVYGRADIAVAPLTITLVREEVIDFSKP 517

  Fly   338 HNFECLTFL--TPESSTDNSWQTFILPFSAGMWVGVLLSLFVVGTVFYAISFLNAI---INGNVS 397
            .....::.:  .|:.|....: :|:.|.:..:|:.::.:...|..|.:.:|..:..   ::.|..
Zfish   518 FMSLGISIMIKKPQKSKPGVF-SFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLDDNEE 581

  Fly   398 SEFFRCLRPNRNVPMDPKIYRRISFRIAISRYRSSKGDRMPRDLFDGYTNCILLTYSMLLYVALP 462
            ::       :...|.||                       |.|.  |..|.:..:....:.....
Zfish   582 TK-------DPQTPPDP-----------------------PNDF--GIFNSLWFSLGAFMQQGCD 614

  Fly   463 RMPRNWPLRVLTGWYWIYCILLVATYRASFTAILANPAARVTIDTLEDLLR-SHIPPST---GAT 523
            ..||:...|::.|.:|.:.::::::|.|:..|.|........|::.|||.: :.|...|   |:|
Zfish   615 ISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIAYGTLDSGST 679

  Fly   524 ENRQFFLEANDEVARKVGEKME-----VF-GYSDDLTSRI--AKGQCAYYDNEFYLRYLRV---- 576
              ::||..:...|..|:...|:     || ..:.|..:|:  :||:.|:........|:..
Zfish   680 --KEFFRRSKIAVYEKMWSYMKSAEPSVFVKTTPDGVARVRKSKGKFAFLLESTMNEYIEQRKPC 742

  Fly   577 --------ADESGSALHIMKECVLYMPVVLAMEKNSALKPRVDASIQHLAEGGLI----AKWLKD 629
                    .|..|..              :|..|.|||:..|:.::..|.|.||:    .||..|
Zfish   743 DTMKVGGNLDSKGYG--------------VATPKGSALRSAVNLAVLKLNEQGLLDKLKNKWWYD 793

  Fly   630 AIEHLPAEALAQQEALMNIQKFWSSFVALLIGYVI------SMLTLLAERWHF 676
            ..|.......::.:|.......|.:.:...:...:      .:|..|..:|.:
Zfish   794 KGECGSGGGDSKHKARCPTVSLWLTDIRTPVNLAVLKLSEQGILDKLKNKWWY 846

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68a	NP_648455.2	Lig_chan	367..661	CDD:459656	60/324 (19%)
gria3a	XP_073805840.1	None