Protein Alignment Ir68a and Grin2c

DIOPT Version :9

• Sequence 1: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: XP_017169765.1
• Gene: Grin2c / 14813
• MGIID: 95822
• Length: 1307
• Species: Mus musculus
• Alignment Length: 587
• Identity: 108/587 - (18%)
• Similarity: 202/587 - (34%)
• Gaps: 147/587 - (25%)

  Fly   191 VLVMKNIANWEL-GKGLNGRILFADKTSNLFGTSL-PVAISEH---------------------- 231
            |:.:.....||: |:..:|.:.........:.||| ||..|.|
Mouse   422 VIALNRHRLWEMVGRWDHGVLYMKYPVWPRYSTSLQPVVDSRHLTVATLEERPFVIVESPDPGTG 486

  Fly   232 ------VPMVLWANATKS-----------FQGVEVEIMNALGKALNFKPVYYKPNQTENMDWTEL 279
                  ||....:|.|.|           .:|..::|:..|.|.:.|....|
Mouse   487 GCVPNTVPCRRQSNHTFSSGDITPYTKLCCKGFCIDILKKLAKVVKFSYDLY------------- 538

  Fly   280 DGGASVAYGSGNPDGYAQNGTH------IDSMLVDEVAAHSARFAIGDLHLFQVYLKLVELSAPH 338
                           ...||.|      :.:.::.||....|..|||.|.:.:...::::.|.|.
Mouse   539 ---------------LVTNGKHGKRVRGVWNGMIGEVYYKRADMAIGSLTINEERSEIIDFSVPF 588

  Fly   339 NFECLTFLTPESSTDNSWQTFILPFSAGMWVGVLLSLFVVGTVFYAISFLNAIINGNVSSEFFRC 403
            ....::.:...|:...|...|:.|:|..:||    .:||:.....||:..        ..|:|..
Mouse   589 VETGISVMVARSNGTVSPSAFLEPYSPAVWV----MMFVMCLTVVAITVF--------MFEYFSP 641

  Fly   404 LRPNRNVPMDPKIYRRISFRIAISRYRSSKGDRMPRDLFDGYTNCILLTYSMLLYVALP-RMPRN 467
            :..|:|:                     :||.:.....|. ....:.|.::::...::| ..||.
Mouse   642 VSYNQNL---------------------TKGKKSGGPSFT-IGKSVWLLWALVFNNSVPIENPRG 684

  Fly   468 WPLRVLTGWYWIYCILLVATYRASFTAILANPAARVTIDTLEDLL----RSHIPP------STGA 522
            ...:::...:..:.::.:|:|.|:..|.:.......|:..|.|..    :...||      ..|:
Mouse   685 TTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKKFQRPQDQYPPFRFGTVPNGS 749

  Fly   523 TEN--RQFFLEANDEVARKVGEKMEVFGYSDDLTS------RIAKGQCAYYDNEFYLRYLRVADE 579
            ||.  |..:.:.:..:.:.....:|     |.|||      .:::...|:..:...|.|:...||
Mouse   750 TERNIRSNYRDMHTHMVKFNQRSVE-----DALTSLKMGARHVSRKLDAFIYDAAVLNYMAGKDE 809

  Fly   580 SGSALHIMKECVLYMP-VVLAMEKNSALKPRVD-ASIQHLAEG---GLIAKWLKDAIEHLPAEAL 639
            ....:.|....|.... ..:||:|:|..|..:| |.:|.|.:|   .|...||.....:...|.:
Mouse   810 GCKLVTIGSGKVFATTGYGIAMQKDSHWKRAIDLALLQFLGDGETQKLETVWLSGICHNEKNEVM 874

  Fly   640 AQQEALMNIQKFWSSFVALLIGYVISMLTLLAER---WHFKHIVMKHPMYD---VYNPSLYYNFK 698
            :.:   ::|......|..||:...:::|....|.   |..:|.|......|   .::..:|..|.
Mouse   875 SSK---LDIDNMAGVFYMLLVAMGLALLVFAWEHLVYWKLRHSVPSSSQLDFLLAFSRGIYSCFN 936

  Fly   699 RI 700
            .:
Mouse   937 GV 938

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68a	NP_648455.2	Lig_chan	429..661	CDD:278489	50/255 (20%)
Grin2c	XP_017169765.1	PBP1_iGluR_NMDA_NR2	90..446	CDD:380601	5/23 (22%)
		PBP2_iGluR_NMDA_Nr2	462..868	CDD:270436	85/472 (18%)
		NMDAR2_C	905..>980	CDD:371139	6/34 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846325
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830