Protein Alignment Ir68a and Grik5

DIOPT Version :9

• Sequence 1: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: XP_030098003.1
• Gene: Grik5 / 14809
• MGIID: 95818
• Length: 1003
• Species: Mus musculus
• Alignment Length: 642
• Identity: 124/642 - (19%)
• Similarity: 222/642 - (34%)
• Gaps: 205/642 - (31%)

  Fly    66 YD----RIFFESVGRRVIPFFVMRTNESDDLQRPSRQVELFVKAIKSSDCELNVITILNGWQVQR 126
            ||    |:.|.|.|:        |||.:..:...||                         |..|
Mouse   378 YDGLTGRVEFNSKGQ--------RTNYTLRILEKSR-------------------------QGHR 409

  Fly   127 FLGYIYDNRSLNMQKKFVLLHDLRLFESDMIHLWSVFIDAIFLKRQLDNKYTISTIAFPGILSGV 191
            .:|..|.||:|.|.                    :..:| |.|.:.|.||    |:....||...
Mouse   410 EIGVWYSNRTLAMN--------------------ATTLD-INLSQTLANK----TLVVTTILENP 449

  Fly   192 LVMKNIANWELGKGLNGRILFADKTSNLFGTSLPVAISEHVPMVLWANATKSFQGVEVEIMNALG 256
            .||:. .|::   .|:|                                .:.|:|..|:::..|.
Mouse   450 YVMRR-PNFQ---ALSG--------------------------------NERFEGFCVDMLRELA 478

  Fly   257 KALNFKPVYYKPNQTENMDWTELDGGASVAYGSGNPDGYAQNGTHIDSMLVDEVAAHSARFAIGD 321
            :.|.|:   |:....|       ||    .||:..|:| :..|     |:.:.:....|..|:..
Mouse   479 ELLRFR---YRLRLVE-------DG----LYGAPEPNG-SWTG-----MVGELINRQKADLAVAA 523

  Fly   322 LHLFQVYLKLVELSAPHNFECLTFLT--------PESSTDNSWQTFILPFSAGMWVGVLLSLFVV 378
            ..:.....|:::.|.|       |:|        ........:.:|:.|||..:|:.:||:...|
Mouse   524 FTITAEREKVIDFSKP-------FMTLGISILYRVHMGRKPGYFSFLDPFSPAVWLFMLLAYLAV 581

  Fly   379 GTVFYAISFLNAIINGNVSSEFFR---CLRPNRNVPMDPKIYRRISFRIAISRYRSSKGDRMPRD 440
            ..|.:..:.|:..       |::.   |||..                              |..
Mouse   582 SCVLFLAARLSPY-------EWYNPHPCLRAR------------------------------PHI 609

  Fly   441 LFDGYT--NCILLTYSMLLYVALPRMPRNWPLRVLTGWYWIYCILLVATYRASFTAILANPAARV 503
            |.:.||  |.:.......:......|||....|.::|.:|.:.::::::|.|:..|.|......|
Mouse   610 LENQYTLGNSLWFPVGGFMQQGSEIMPRALSTRCVSGVWWAFTLIIISSYTANLAAFLTVQRMEV 674

  Fly   504 TIDTLEDLL-RSHIPPST---GATENRQFFLEANDEVARKVGEKME-----VFGYS-DDLTSRIA 558
            .:::.:||. :::|...|   |:|  ..||..:..:..:::...|:     ||..| ::..:|:.
Mouse   675 PVESADDLADQTNIEYGTIHAGST--MTFFQNSRYQTYQRMWNYMQSKQPSVFVKSTEEGIARVL 737

  Fly   559 KGQCAYY----DNEFYLRYLRVADESGSALHIMKECVLYMPVVLAMEKNSALKPRVDASIQHLAE 619
            ..:.|:.    .||::.|......:.|..|. .|...:.||:      .|..:..:..:|..|.|
Mouse   738 NSRYAFLLESTMNEYHRRLNCNLTQIGGLLD-TKGYGIGMPL------GSPFRDEITLAILQLQE 795

  Fly   620 GG----LIAKWLKDAIEHLPAEALAQQEALMNIQKFWSSFVALLIGYVISMLTLLAE 672
            ..    |..||.:..  ..|.|...:.:.| .::.....||.|:.|.:|::...:.|
Mouse   796 NNRLEILKRKWWEGG--RCPKEEDHRAKGL-GMENIGGIFVVLICGLIIAVFVAVME 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68a	NP_648455.2	Lig_chan	429..661	CDD:278489	51/251 (20%)
Grik5	XP_030098003.1	PBP1_iGluR_Kainate_KA1_2	23..424	CDD:380616	19/98 (19%)
		Periplasmic_Binding_Protein_Type_2	437..808	CDD:419667	92/483 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846328
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740