Protein Alignment Ir68a and Grik3

DIOPT Version :9

• Sequence 1: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_001074566.1
• Gene: Grik3 / 14807
• MGIID: 95816
• Length: 919
• Species: Mus musculus
• Alignment Length: 536
• Identity: 112/536 - (20%)
• Similarity: 193/536 - (36%)
• Gaps: 152/536 - (28%)

  Fly   194 MKNIANWELGKGLN------GRILFADKTSNLFGTSLPVAISEHVPMVLWANATKS------FQG 246
            ::.:..|....|||      ||  ..:.|.:|...||.|......|.|::..:.::      |:|
Mouse   402 LEKVGVWSPADGLNITEVAKGR--GPNVTDSLTNRSLIVTTVLEEPFVMFRKSDRTLYGNDRFEG 464

  Fly   247 VEVEIMNALGKALNFKPVYYKPNQTENMDWTELDGGASVAYGSGNPDGYAQNGTHIDSMLVDEVA 311
            ..::::..|...|.|.   |:....|       ||    .||:.:..| ..||      :|.|:.
Mouse   465 YCIDLLKELAHILGFS---YEIRLVE-------DG----KYGAQDDKG-QWNG------MVKELI 508

  Fly   312 AHSARFAIGDLHLFQVYLKLVELSAPHNFECLTFLT--------PESSTDNSWQTFILPFSAGMW 368
            .|.|..|:..|.:..|..|.::.|.|       |:|        ..:.|:.|..:|:.|.|..:|
Mouse   509 DHKADLAVAPLTITHVREKAIDFSKP-------FMTLGVSILYRKPNGTNPSVFSFLNPLSPDIW 566

  Fly   369 VGVLLSLFVVGTVFYAISFLNAIINGNVSSEFFRCLRPNRNVPMDPKIYRRISFRIAISRYRSSK 433
            :.|||:...|..|.:.|:                                |.|
Mouse   567 MYVLLAYLGVSCVLFVIA--------------------------------RFS------------ 587

  Fly   434 GDRMPRDLFDGY----------TNCILLT---YSM--LLYVALPRMPRNWPLRVLTGWYWIYCIL 483
                |.:.:|.:          .|..||.   :.|  |:......||:....|::.|.:|.:.::
Mouse   588 ----PYEWYDAHPCNPGSEVVENNFTLLNSFWFGMGSLMQQGSELMPKALSTRIIGGIWWFFTLI 648

  Fly   484 LVATYRASFTAILANPAARVTIDTLEDLLR----SHIPPSTGATENRQFFLEANDEVARKVGEKM 544
            ::::|.|:..|.|........||:.:||.:    .:.....|||  ..||.::      |:....
Mouse   649 IISSYTANLAAFLTVERMESPIDSADDLAKQTKIEYGAVKDGAT--MTFFKKS------KISTFE 705

  Fly   545 EVFGYSDDLTSRIAKGQCAYYDNEFYLRYLRVAD-----ESGSALHI-MKECVLYMPVVLAMEK- 602
            :::.:.....|.:.|      :||..::....||     ||.:..:| .:.|.|.....|...|
Mouse   706 KMWAFMSSKPSALVK------NNEEGIQRTLTADYALLMESTTIEYITQRNCNLTQIGGLIDSKG 764

  Fly   603 -------NSALKPRVDASIQHLAEGGLI----AKWLKDAIEHLPAEALAQQEALMNIQKFWSSFV 656
                   .|..:.::..:|..|.|...:    .||.:.:  ..|.|...:..|| .|||....|:
Mouse   765 YGIGTPMGSPYRDKITIAILQLQEEDKLHIMKEKWWRGS--GCPEEENKEASAL-GIQKIGGIFI 826

  Fly   657 ALLIGYVISMLTLLAE 672
            .|..|.|:|:|..:.|
Mouse   827 VLAAGLVLSVLVAVGE 842

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68a	NP_648455.2	Lig_chan	429..661	CDD:278489	54/268 (20%)
Grik3	NP_001074566.1	PBP1_iGluR_Kainate_GluR5_7	34..417	CDD:107388	4/14 (29%)
		PBP2_iGluR_Kainate_GluR7	433..801	CDD:270441	90/457 (20%)
		Glutamate binding. /evidence=ECO:0000250	690..692		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846323
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740