Protein Alignment Ir68a and Grid1

DIOPT Version :10

• Sequence 1: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_032192.2
• Gene: Grid1 / 14803
• MGIID: 95812
• Length: 1009
• Species: Mus musculus
• Alignment Length: 525
• Identity: 102/525 - (19%)
• Similarity: 195/525 - (37%)
• Gaps: 123/525 - (23%)

  Fly   194 MKNIANWELGKGLNGRILFADKTSNLFGTSLPVAISEHVPMVLWA----NATKSFQGVEVEIMNA 254
            |:.:|.|:..|||||.:......|.|.|.:|.|......|.|:.|    ...|.::|..:::::|
Mouse   409 MRKLATWDSEKGLNGSLQERPMGSRLQGLTLKVVTVLEEPFVMVAENILGQPKRYKGFSIDVLDA 473

  Fly   255 LGKALNFK-PVYYKP-----NQTENMDWTELDGGASVAYGSGNPDGYAQNGTHIDSMLVDEVAAH 313
            |.|||.|| .:|..|     :|..|..|                     ||      ::.|:.:.
Mouse   474 LAKALGFKYEIYQAPDGRYGHQLHNTSW---------------------NG------MIGELISK 511

  Fly   314 SARFAIGDLHLFQVYLKLVELSAPHNFECLTFLTPESSTDNSWQTFILPFSAGMWVGVLLSLFVV 378
            .|..||..:.:......:|:.|..:....:..|..:.....|..:...||...:|..:..::.||
Mouse   512 RADLAISAITITPERESVVDFSKRYMDYSVGILIKKPEEKISIFSLFAPFDFAVWACIAAAIPVV 576

  Fly   379 GTVFYAISFLNAIINGNVSSEFFRCLRPNRNVPMDPKIYRRISFRIAISRYRSSKGDRMPRDLFD 443
            |.:.:.::.:.|:.:.:.:..     ||:.:..:...|:      |....:....|:
Mouse   577 GVLIFVLNRIQAVRSQSATQP-----RPSASATLHSAIW------IVYGAFVQQGGE-------- 622

  Fly   444 GYTNCILLTYSMLLYVALPRMPRNWPLRVLTGWYWIYCILLVATYRASFTAILA-----NPAARV 503
                      |.:..||         :|::.|.:|::.:::.::|.|:..|.|.     ||
Mouse   623 ----------SSVNSVA---------MRIVMGSWWLFTLIVCSSYTANLAAFLTVSRMDNP---- 664

  Fly   504 TIDTLEDLLRSHIPPSTGATENR---QFF-------LEAND---EVARKVGEKMEVFGYSDDLTS 555
             |.|.:||.: .:..|.|...:.   ::|       ||.:.   |:.|.:.:.    |.:|:..|
Mouse   665 -IRTFQDLSK-QLEMSYGTVRDSAVYEYFRAKGTNPLEQDSTFAELWRTISKN----GGADNCVS 723

  Fly   556 -------RIAKGQCAYYDNEFYLRYLRVADESGSALHIMKECVLYMPVVLAMEKNSALKPRVDAS 613
                   :..||..|:..:...:.|..:.|:..| :.::...:......:|::..|..:......
Mouse   724 NPSEGIRKAKKGNYAFLWDVAVVEYAALTDDDCS-VTVIGNSISSKGYGIALQHGSPYRDLFSQR 787

  Fly   614 IQHLAEGG----LIAKWLK-----DAIEHLPAEALAQQEALMNIQKFWSSFVALLIGYVISMLTL 669
            |..|.:.|    |..||..     |...|...:...:.   :.:..|...|..|.||.:::.|..
Mouse   788 ILELQDTGDLDVLKQKWWPHTGRCDLTSHSSTQTEGKS---LKLHSFAGVFCILAIGLLLACLVA 849

  Fly   670 LAERW 674
            ..|.|
Mouse   850 ALELW 854

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68a	NP_648455.2	Lig_chan	367..661	CDD:459656	55/327 (17%)
Grid1	NP_032192.2	Interaction with CBLN1. /evidence=ECO:0000269|PubMed:27418511	21..436		10/26 (38%)
		PBP1_iGluR_delta_1	25..425	CDD:380615	8/15 (53%)
		PBP2_iGluR_delta_1	436..806	CDD:270448	82/445 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	931..960