Protein Alignment Ir68a and grin2b

DIOPT Version :9

• Sequence 1: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: XP_017948700.2
• Gene: grin2b / 100490580
• XenbaseID: XB-GENE-949327
• Length: 1449
• Species: Xenopus tropicalis
• Alignment Length: 469
• Identity: 94/469 - (20%)
• Similarity: 169/469 - (36%)
• Gaps: 107/469 - (22%)

  Fly   245 QGVEVEIMNALGKALNFKPVYY-----KPNQTENMDWTELDGGASVAYGSGNPDGYAQNGTHIDS 304
            :|..::|:..:.|.:.|....|     |..:..|..|                     ||
 Frog   455 KGFCIDILKKIAKTVKFTYDLYLVTNGKHGKKINGTW---------------------NG----- 493

  Fly   305 MLVDEVAAHSARFAIGDLHLFQVYLKLVELSAPHNFECLTFLTPESSTDNSWQTFILPFSAGMWV 369
             ::.||....|..|:|.|.:.:...::|:.|.|.....::.:...|:...|...|:.||||.:||
 Frog   494 -MIGEVVTKRAYMAVGSLTINEERSEVVDFSVPFIETGISVMVSRSNGTVSPSAFLEPFSADVWV 557

  Fly   370 GVLLSLFVVGTV-FYAISFLNAIINGNVSSEFFRCLRPNRNVPMDPKIYRRISFRIAISRYRSSK 433
            .:.:.|.:|..| .:...:.:.:       .:.|||...|. |..|      ||.|.
 Frog   558 MMFVMLLIVSAVAVFVFEYFSPV-------GYNRCLADGRE-PGGP------SFTIG-------- 600

  Fly   434 GDRMPRDLFDGYTNCILLTYSMLLYVALP-RMPRNWPLRVLTGWYWIYCILLVATYRASFTAILA 497
                         ..|.|.:.::...::| :.|:....:::...:..:.::.:|:|.|:..|.:.
 Frog   601 -------------KAIWLLWGLVFNNSVPVQNPKGTTSKIMVSVWAFFAVIFLASYTANLAAFMI 652

  Fly   498 NPAARVTIDTLED-----------LLRSHIPPSTGATEN--RQFFLEANDEVA----RKVGEKME 545
            .......:..|.|           ..|....|: |:||.  |..:||.:..:.    |.|.:.:
 Frog   653 QEEYVDQVSGLSDKKFQRPNDFSPAFRFGTVPN-GSTERNIRNNYLEMHSYMVKFNQRSVQDAL- 715

  Fly   546 VFGYSDDLTSRIAKGQCAYYDNEFYLRYLRVADESGSALHIMKECVLYMP-VVLAMEKNSALKPR 609
                   |:.:..|.....|| ...|.|:...||....:.|....|.... ..:|::|:|..|.:
 Frog   716 -------LSLKTGKLDAFIYD-AAVLNYMAGRDEGCKLVTIGSGKVFATTGYGIAIQKDSGWKRQ 772

  Fly   610 VDASIQHLAEGG----LIAKWLKDAIEHLPAEALAQQEALMNIQKFWSSFVALLIGYVISMLTLL 670
            ||.:|..|...|    |.|.||.....:...|.::.|   ::|......|..|.....:|::|.:
 Frog   773 VDLAILQLFGDGEMEELEALWLTGICHNEKNEVMSSQ---LDIDNMAGVFYMLAAAMALSLITFI 834

  Fly   671 AER---WHFKHIVM 681
            .|.   |..:|..|
 Frog   835 MEHLFFWQLRHCFM 848

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68a	NP_648455.2	Lig_chan	429..661	CDD:278489	48/254 (19%)
grin2b	XP_017948700.2	PBP1_iGluR_NMDA_NR2	28..383	CDD:380601
		PBP2_iGluR_NMDA_Nr2	400..800	CDD:270436	83/416 (20%)
		NMDAR2_C	837..1449	CDD:402274	3/12 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910