Protein Alignment Ir68a and grik3

DIOPT Version :10

• Sequence 1: NP_648455.2
• Gene: Ir68a / 39269
• FlyBaseID: FBgn0036150
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: XP_017206939.1
• Gene: grik3 / 100334689
• ZFINID: ZDB-GENE-211021-1
• Length: 991
• Species: Danio rerio
• Alignment Length: 712
• Identity: 133/712 - (18%)
• Similarity: 223/712 - (31%)
• Gaps: 242/712 - (33%)

  Fly    27 PAPLSGYEMQLKILLQKILWVANVKRCFAVITDDLHYPIYDRIFFESVGRRVIPFFVMRTNESDD 91
            |.|.||       ||:.|:...      |.:|       ||.:...||..:..|...:     :.
Zfish   301 PKPDSG-------LLEGIMTTD------AALT-------YDAVHIVSVSYQHAPQMTV-----NS 340

  Fly    92 LQ----RPSRQVELFVKAIKSSDCELNVITILNGWQVQRFLGYIYDNRSLNMQKKFVLLHDLRLF 152
            ||    :|.|....|:..||.|.           |  ....|.:..||:..::..|.|
Zfish   341 LQCHRHKPWRFGGRFMSFIKESH-----------W--DGLTGRLCFNRTTGLRTDFDL------- 385

  Fly   153 ESDMIHLWSVFIDAIFLKRQLDNKYTISTIAFPGILSGVLVMKNIANWELGKGLN----GRILFA 213
                        |.:.||..                    .::.:..|....|||    .|....
Zfish   386 ------------DIVSLKED--------------------GLQKVGKWSASGGLNITEVPRQNGM 418

  Fly   214 DKTSNLFGTSLPVAISEHVPMVLWANATKS------FQGVEVEIMNALGKALNFK-PVYYKPNQT 271
            :.|.:|...||.:......|.|:...:.|:      |:|..::::..|...|.|. .::..|
Zfish   419 NITDSLSNRSLVITTILEEPYVMLKKSDKALVGNDRFEGFCIDLLKELASILGFSYEIHLVP--- 480

  Fly   272 ENMDWTELDGGASVAYGSGNPDGYAQNGTHIDSMLVDEVAAHSARFAIGDLHLFQVYLKLVELSA 336
                    ||    .||..:..| ..||      ::.|:..|.|..|:..|.:..:..|.::.|.
Zfish   481 --------DG----KYGFQDDKG-QWNG------MIRELMEHRADLAVAPLTITFMREKAIDFSK 526

  Fly   337 PH-NFECLTFLTPESSTDNSWQTFILPFSAGMWVGVLLSLFVVGTVFYAISFLNAIINGNVSSEF 400
            |. |..........:||::.:.:|:.|.:..:||.:||:...|..|.:.|:
Zfish   527 PFLNTGISILYRKPNSTNSGFFSFLNPMTPDIWVYILLAYLGVSCVLFVIA-------------- 577

  Fly   401 FRCLRPNRNVPMDPKIYRRISFRIAISRYRSSKGDRMPRDLFDGY----------TNCILLT--- 452
                              |.|                |.:.:|.:          .|..||.
Zfish   578 ------------------RFS----------------PYEWYDAHPCNPGSDVVENNFTLLNSFW 608

  Fly   453 --YSMLLYVALPRMPRNWPLRVLTGWYWIYCILLVATYRASFTAILANPAARVTIDTLEDLLR-- 513
              ...|:......||:....|::.|.:|.:.::::::|.|:..|.|........:|:.:||.:
Zfish   609 FGVGSLMQQGSELMPKALSTRIIGGIWWFFTLIIISSYTANLAAFLTVERMDSPVDSADDLAKQT 673

  Fly   514 --SHIPPSTGATENRQFFLEANDEVARKVGEKMEVFGYSDDLTS----------RIAKGQCAYYD 566
              .:.....|||  ..||.::.....    |||..|..|...||          |:.|...|...
Zfish   674 KIEYGVVKDGAT--MSFFKKSRVSTF----EKMWAFMSSRQSTSFVKSIEDGIQRVLKSDYALLM 732

  Fly   567 NEFYLRYLR-----------VADESGSALHIMKECVLYMPVVLAMEKNSALKPRVDASIQHLAEG 620
            ....:.|:.           :.|..|..              :...|.|..:.::..:|..:.|.
Zfish   733 ESTTIEYVTRRNCNLTQVGGIIDSKGYG--------------IGTPKGSPYRDKITIAILGILED 783

  Fly   621 G----LIAKW------LKDAIEHLPAEALAQQEALMNIQKFWSSFVALLIGYVISMLTLLAE 672
            |    |..||      |:|.         ..:...|.||.....|:.|..|.|:|:...:.|
Zfish   784 GRLHMLKEKWWSGSSCLEDE---------RYETGPMGIQNLGGIFIVLASGLVLSVFVAIGE 836

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir68a	NP_648455.2	Lig_chan	367..661	CDD:459656	60/343 (17%)
grik3	XP_017206939.1	PBP1_iGluR_Kainate	32..410	CDD:380605	35/185 (19%)
		Periplasmic_Binding_Protein_Type_2	426..794	CDD:473866	83/457 (18%)