DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42671 and esc1

DIOPT Version :9

Sequence 1:	NP_001287029.1	Gene:	CG42671 / 39268	FlyBaseID:	FBgn0261553	Length:	1302	Species:	Drosophila melanogaster
Sequence 2:	NP_593230.1	Gene:	esc1 / 2543286	PomBaseID:	SPAC56F8.16	Length:	413	Species:	Schizosaccharomyces pombe

Alignment Length:	458	Identity:	93/458 - (20%)
Similarity:	161/458 - (35%)	Gaps:	148/458 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 ADTTPENIKKIAEIIDSPDGTTSANSPIPSP---RHVQLR-NPMNPGFVGLGAAIDDSCGKFCLG 142
            |.:||.:.:::.        .|..:.|:.:|   :|.|.| .|:|                 ||.
pombe    34 ASSTPYSPQQVP--------LTHNSYPLSTPSSFQHGQTRLPPIN-----------------CLA 73

  Fly   143 KP-------------PPSPAEKAAAAQSRANQQH---------------GTPPGNSNSSNSNHKS 179
            :|             |.|.:..:|...:.|:..|               ..||.||.:|.::.|.
pombe    74 EPFNRPQPWHSNSAAPASSSPTSATLSTAAHPVHTNAAQVAGSSSSYVYSVPPTNSTTSQASAKH 138

  Fly   180 AAAVEEENSSESNTTTKASLAFTID--HFDASENDSAAQAARYKNMMERFQNRHKRGASMSKLET 242
            :|.....:..:|.|.|.:    |.|  ..|.|.:||.:.:|...|            ||.:...|
pombe   139 SAVPHRSSQFQSTTLTPS----TTDSSSTDVSSSDSVSTSASSSN------------ASNTVSVT 187

  Fly   243 EKDNTTATSNSGRQSQRSSL----DAGSSMADDVSSLTAATPSSEQAPPVQVKMRVRDRSASRVR 303
            ...:::||....:.||:..|    ||.::....|.:           .|:|..|.|..:..|...
pombe   188 SPASSSATPLPNQPSQQQFLVSKNDAFTTFVHSVHN-----------TPMQQSMYVPQQQTSHSS 241

  Fly   304 DAS-KRHSWSP------RSSANATEAVAAPAPRPASRSKLPPPPA------ATKGTSNMVAN--R 353
            .|| :..|.:|      :.|.:..:..:.|..:..|.|..|..|:      |.:..|::.||  .
pombe   242 GASYQNESANPPVQSPMQYSYSQGQPFSYPQHKNQSFSASPIDPSMSYVYRAPESFSSINANVPY 306

  Fly   354 TANQFTPRSTAMQLALRQVEMLCPQPPLVDGKPSAENDAVSEAGTYTLDGDNYT-------EEQK 411
            ..|::          ||:|..|.|..|             ...|.||.:.:..|       :.:|
pombe   307 GRNEY----------LRRVTSLVPNQP-------------EYTGPYTRNPELRTSHKLAERKRRK 348

  Fly   412 DLMNIDRNLKEAAAKQRPKQLPVKSSRGSNVLEVNYYHETPLQEQLPQQLPAQRSSTGAYLDQLK 476
            ::..:..:||:|.    |.....|||:...:.....|.|         ||.:::.:..||:..|:
pombe   349 EIKELFDDLKDAL----PLDKSTKSSKWGLLTRAIQYIE---------QLKSEQVALEAYVKSLE 400

  Fly   477 SRV 479
            ..:
pombe   401 ENM 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42671	NP_001287029.1	None
esc1	NP_593230.1	HLH	336..386	CDD:278439	12/62 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR22934
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100