DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7600 and AT1G35220

DIOPT Version :9

Sequence 1:	NP_648453.1	Gene:	CG7600 / 39267	FlyBaseID:	FBgn0064766	Length:	928	Species:	Drosophila melanogaster
Sequence 2:	NP_001321751.1	Gene:	AT1G35220 / 840411	AraportID:	AT1G35220	Length:	1005	Species:	Arabidopsis thaliana

Alignment Length:	1054	Identity:	253/1054 - (24%)
Similarity:	408/1054 - (38%)	Gaps:	336/1054 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LQQCVRGNVTWELLPVHLRSVLHNNQRDYEKFVFNYSLKNQLRFRGNLAAKVFRREQRYYELLIQ 91
            :.:.||....||.||..|:|:| .::.::.:.|..:.:|.:|.:....|.||. :|..|||.:::
plant    13 ISKAVREECQWENLPKRLQSIL-GSKDEWHRRVTAHCIKKRLLWNTCFACKVC-KEGEYYEDMMR 75

  Fly    92 KSINGLGAFPYHLADIVTKGLRVTPFNYYLDVLGQLLQSDKSYDTLPNFTAADCLRVLGIGRNEY 156
            .....|..||||||:.|.:.:|::||.||.|::.:::::::.||::|||:|||..|:.||||||:
plant    76 YLRKNLALFPYHLAEYVCRVMRISPFRYYCDMIFEVMRNEQPYDSIPNFSAADAFRLTGIGRNEF 140

  Fly   157 LALISDMKTHTPRSLIFGSRPNPLDFLPRFPVRIHIEPWWRLD-IGYVLEADIRYLSPAERGLLD 220
            :.:::  |..:.:.:...::....||||..||...|:|||.:. :.:.:| :.:.||..|...:|
plant   141 IDIMN--KCRSKKIMWKLNKSIAKDFLPTLPVDFPIDPWWGVCLVNFTIE-EFKKLSEDEMATID 202

  Fly   221 DLIDFGAQPAGKCDHDVVHSLYRKGLIYLDVPISGEDRISIPPLRNFVMNRVSG--DYFENLLYK 283
            .:....|......|.:|:..||::||:|.|||:..:||..:..|..|:.||...  |..|.|||.
plant   203 KICKEEANAYFLFDPEVIKGLYQRGLVYFDVPVYQDDRFKVSKLEGFISNREQSYEDPIEELLYA 267

  Fly   284 IFVSADEHMTIAELAQMLQLELDSVKQAISFICRLGFAHRKEDLVNQTNHSSWEGYNQQQTPDTP 348
            :||.::|:.|:||||..||.::..::.|.||:||||:|.:..|                  |.:.
plant   268 VFVVSNENSTVAELASTLQADVTQLQAAASFVCRLGWAVKLID------------------PSSV 314

  Fly   349 QITPLNYNLHTSSSFEFDQSPKSPKTPKEREKDKDKDSSSIGYLSSDGNTSDFSFANLNTTPQER 413
                    ||....        ||:.....::|..:.|.|..|.|:||               |.
plant   315 --------LHDKIG--------SPRAILSDDEDASRASISSTYRSADG---------------EE 348

  Fly   414 VNNSDEQELSSELEQEDMCAPKQAAPSAAISAAVLPKSGKRVGFLFDSTLTAFLMMGNLSPGLKN 478
            ..:.|  .|.:|             .|.:.|:.|      ||.|:.|:.:|::||||::|||||:
plant   349 AQHGD--NLGTE-------------SSGSRSSHV------RVAFIVDANITSYLMMGSVSPGLKS 392

  Fly   479 HAVTMFEVGKLCEESLDSFLAELEQVSLLDAEGEGDVSRYFAHAVILRSTICSLRHLLPGG---- 539
            ||||::|.|||...|:.....:|.  :|..|:.||::..:..||..||   |.|..|:.||
plant   393 HAVTLYEAGKLGHTSIPDLCQDLS--TLEGAKFEGELQEFANHAFSLR---CVLECLISGGVATD 452

  Fly   540 ----------------------------------------------------------------- 539

plant   453 AIVDTMGSGTLSNDEAVTLLADVNLPDNSGDSLTSQIIEASMVSDAPQEVPLSTEHVPESTKHEA 517

  Fly   540 -----------------------------------------------LDLLRLECLEGLDQQTRD 557
                                                           :|:||.|.|..|...|.|
plant   518 ASSTPSVDTTALTETFSSNLNLQNEGKPIPVEGPDTGKGNKKRKKYRVDILRCESLASLTPATLD 582

  Fly   558 RVLEKKYKFIIA--ASPLTASLSHTFSIPYFGQFLRSSDVAPMWSKLFYNHITGYGPPSLLLCRG 620
            |:..:.|..:::  ..|||..|.......:||....||  ...|.||......|.||.|::|.:|
plant   583 RLFSRDYDIVVSMIPLPLTTVLPGPSGPVHFGPPSHSS--MTQWMKLVLYSTVGIGPLSVILMKG 645

  Fly   621 TVLKTLPRLFLGYGKLLVNILHSDAYVLNSENFRSLNSQLKNGCVLLQGYGIRTAGALHYESFPF 685
            ..|:.||....|..|.::       :..:..:...|.::.:..  |::| ||
plant   646 QCLRMLPAPLAGCEKAII-------WSWDGSSVGGLGNKFEGN--LVKG-GI------------- 687

  Fly   686 QAADTRQAKWAAHRAVHKLSSLLDLRQQCGYITFLNTGVPDLGCEDYELQVRLKPAQRQKRTSIA 750
                          .:|.|:.||    :|.                   .|.::|..:....|
plant   688 --------------LLHCLNCLL----KCS-------------------AVLVQPLSKHDLDS-- 713

  Fly   751 APSKPNHVPTNEVTSFQLKSPDENHFAATPEHG-----PANEFTAPDCSQVLASELAKCSSRADL 810
                     :..:.:..:..|.:|...:.|..|     |..|.|.      |.|.|.|.::..:|
plant   714 ---------SGRIVTLDIPLPLKNSDGSIPHFGDELGLPLEENTK------LNSLLTKLANNMEL 763

  Fly   811 ----------VSQSSVEIEEISPSVVQEEDATEEWTLLDVNFGVPLFDVDTNTRICEQLV--QGL 863
                      :.::...::..||    :.|...||..|.|.||.|||.......||:::|  |.|
plant   764 KTVGYIRLLKLFKAKDSLKHFSP----DNDEKYEWVPLTVEFGFPLFSPKLCNNICKRIVSSQLL 824

  Fly   864 CSDANLEALPAAASQAQVLFLDFVQQC----------LYFEDDPAR----QSVQAARPLPHPRIN 914
            .:|:.:|...|             .||          ||....||.    |..||..|   .|.|
plant   825 QADSLMEQHDA-------------MQCIRKRLKDICALYQATGPAAKLLYQKEQAKEP---TRTN 873

  Fly   915 --LAFENGHVCHWN 926
              :.:.:|   .||
plant   874 KLMNYASG---RWN 884

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7600	NP_648453.1	FAM91_N	32..336	CDD:291320	104/306 (34%)
CG7600	NP_648453.1	FAM91_C	452..922	CDD:291321	127/620 (20%)
AT1G35220	NP_001321751.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	190	1.000	Domainoid score	I944
eggNOG	1	0.900	-	-		E1_KOG3707
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H13388
Inparanoid	1	1.050	310	1.000	Inparanoid score	I741
OMA	1	1.010	-	-		QHG54137
OrthoDB	1	1.010	-	-		D164905at2759
OrthoFinder	1	1.000	-	-		FOG0005587
OrthoInspector	1	1.000	-	-		oto3325
orthoMCL	1	0.900	-	-		OOG6_104766
Panther	1	1.100	-	-	LDO	PTHR28441
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4558
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.930