DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ube3a and GAS7

DIOPT Version :9

Sequence 1:NP_648452.1 Gene:Ube3a / 39266 FlyBaseID:FBgn0061469 Length:973 Species:Drosophila melanogaster
Sequence 2:NP_958839.1 Gene:GAS7 / 8522 HGNCID:4169 Length:476 Species:Homo sapiens


Alignment Length:351 Identity:65/351 - (18%)
Similarity:109/351 - (31%) Gaps:126/351 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   407 WAAHCSDQLHSLIAACQQQITLQVLLDEESM------RENESII------SVTKVLKIVFYANIL 459
            |.....|.|.....|...|     ||::..|      .|::::|      |........:|.|..
Human    40 WEGEKEDGLRGWFPASYVQ-----LLEKPGMVPPPPGEESQTVILPPGWQSYLSPQGRRYYVNTT 99

  Fly   460 ASEL--ERPSC-----------RVPLEDRTEAATASGSAA------------------------- 486
            .:|.  ||||.           |..|........|||:.|                         
Human   100 TNETTWERPSSSPGIPASPGSHRSSLPPTVNGYHASGTPAHPPETAHMSVRKSTGDSQNLGSSSP 164

  Fly   487 ----VEDDLFVYNSLLEPHMPKFAEDQFEKELQVSAID---------------------CRKPL- 525
                .:::....|.:..||.....|.|..|..:.|..|                     .:|.| 
Human   165 SKKQSKENTITINCVTFPHPDTMPEQQLLKPTEWSYCDYFWADKKDPQGNGTVAGFELLLQKQLK 229

  Fly   526 -IPLEEFYNEALSENIQMHHDY------LSYKTLAMESEIGSGHANYFSFMLYAFI---LTPSTK 580
             ..:::..:|.:.|.|::..||      ||..:||.:.|...|.|       :|.:   |....:
Human   230 GKQMQKEMSEFIRERIKIEEDYAKNLAKLSQNSLASQEEGSLGEA-------WAQVKKSLADEAE 287

  Fly   581 VDALYYDSRMRMYSERYSSLHSILNNIGQVGQEDNPRPDLKLTVRRDQL-------------IND 632
            |       .::..::.:|.:...|.|..:..::|..:.|..:...|.||             :.:
Human   288 V-------HLKFSAKLHSEVEKPLMNFRENFKKDMKKCDHHIADLRKQLASRYASVEKARKALTE 345

  Fly   633 ALIGLEM------VAMSN--PKDLKK 650
            ....|||      :.:||  .:|:||
Human   346 RQRDLEMKTQQLEIKLSNKTEEDIKK 371

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ube3aNP_648452.1 AZUL 40..94 CDD:293166
HECTc 620..971 CDD:238033 11/52 (21%)
HECTc 647..970 CDD:214523 3/4 (75%)
GAS7NP_958839.1 SH3_GAS7 5..57 CDD:212763 4/16 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 100..171 11/70 (16%)
WW_FCH_linker 109..201 CDD:374680 14/91 (15%)
F-BAR_GAS7 214..446 CDD:153333 33/172 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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