Protein Alignment Ube3a and UPL1

DIOPT Version :10

• Sequence 1: NP_648452.1
• Gene: Ube3a / 39266
• FlyBaseID: FBgn0061469
• Length: 973
• Species: Drosophila melanogaster
• Sequence 2: NP_001185245.1
• Gene: UPL1 / 842036
• AraportID: AT1G55860
• Length: 3681
• Species: Arabidopsis thaliana
• Alignment Length: 1200
• Identity: 283/1200 - (23%)
• Similarity: 452/1200 - (37%)
• Gaps: 374/1200 - (31%)

  Fly    49 HQLQSGCGNANCSNANCASSGKVAPMTPNEVAA-------------RALQLFSQDAQLCEAFTSE 100
            ::|.|.....|..|......|.:....| ||.|             ||..|.||.||..:..|.|
plant  2577 NELSSMEATENVRNDEQVEEGSLDGRAP-EVNAIDPTFLEALPEDLRAEVLASQQAQSVQPPTYE 2640

  Fly   101 ANSPQDVD-----MLSPNDSS------------SSSSGSSTSTITSASTTTTTSRQSQ-----ST 143
            .....|:|     .|.|:..:            ..|.|.:.. :.:||...|.....:     ::
plant  2641 PPPVDDIDPEFLAALPPDIQTEVLAQQRAQRMVQQSQGQAVD-MDNASIIATLPADLREEVLLTS 2704

  Fly   144 PAAVVVPVSSPYLTQSVPQLDIAGAEHSSGDSEPCTPTLAPVHSLD--ANSLIALYEQCRAADSY 206
            ..||:..:.||.|.::....|.|.:.:.:..|     .....|.|:  .|.|           .|
plant  2705 SEAVLAALPSPLLAEAQMLRDRAMSHYQARSS-----VFGSSHRLNNRRNGL-----------GY 2753

  Fly   207 DRIC---HAIGV------VFSSVDRLG---------------KSFI---RSAEPAASSSLQELLA 244
            :|:.   ..:||      |.||.|.|.               ||.|   |.|:|.....||.||.
plant  2754 NRLTGMDRGVGVTIGQRAVSSSADGLKVKEIEGDPLVNADALKSLIRLLRLAQPLGKGLLQRLLL 2818

  Fly   245 NSPGALNKEQLRTLEGEHDKDEDSTQQVDEQSESAANATATAESVE---SEAEPEEEDDDVCSSQ 306
            |                                ..|::...|..|:   ....||.|      :.
plant  2819 N--------------------------------LCAHSFTRANLVQLLLDMIRPEME------TS 2845

  Fly   307 SSDTLVDLPGLRRVQRLLFGCQ------------------IRAITEKLT---SSVIQLSDWVIYM 350
            .|:..:..|     || |:|||                  .|.:.|.||   ::...::|.:.|.
plant  2846 PSELAITNP-----QR-LYGCQSNVVYGRSQLLNGLPPLVFRRVLEVLTYLATNHSAVADMLFYF 2904

  Fly   351 ----------RTDWERVIHCLVICFDLATNTNN----SVVDMDYLDRVLPKLCQAAS-------A 394
                      |...|:|.|        .|::.:    .||.:..|:|  |:|.|:.|       .
plant  2905 DSSLLSQLSSRKGKEKVTH--------VTDSRDLEIPLVVFLKLLNR--PQLLQSTSHLGLVMGL 2959

  Fly   395 MPVPAQARLARI--WA-----------------------------------------AHCSDQLH 416
            :.|......:||  |:                                         .:|::..:
plant  2960 LQVVVYTAASRIEGWSPSSGVPEKLENKPVGEEASSETRKDAESELVGEADLSVARRKNCAEIYN 3024

  Fly   417 SLIAACQQQI-TLQVLLDEESMRENESIISVT-KVLKIVFYANI------------LASELERPS 467
            ..:...|..: .|.:||..|.:  ::.|.|:. :|||.:...::            |||.|...:
plant  3025 IFLQLPQSDLCNLCILLGYEGL--SDKIYSLAGEVLKKLAAVDVAHRKFFTKELSELASSLSSST 3087

  Fly   468 CR--VPLEDRTEAATASGS---AAVEDDLFVYNSLLEPHMPKFAEDQFEKELQVSAIDCRKPLIP 527
            .|  ..|..:.:.:.::||   |::...|.|.:||..|........:.|.|.:...| .::..:.
plant  3088 VRELATLSSKQKMSRSTGSMAGASILRVLQVLSSLTSPIDESNVGTERETEQEEQNI-MQRLNVA 3151

  Fly   528 LEEFYNEALSENIQMHHDYLSYKTLAMESEIGSG-HANYFS-------------------FMLYA 572
            ||..::| ||:.|.|....|.:...|  |.|..| |....|                   |:|..
plant  3152 LEPLWHE-LSQCISMTELQLDHTAAA--SNINPGDHVLGISPTSSLSPGTQRLLPLIEAFFVLCE 3213

  Fly   573 FILTPSTKVDALYYDSRMRMYSERYSSLHS----------------------------ILNNIGQ 609
            .|.|||    .|..|:.:.....:.||.|.                            :||:.
plant  3214 KIQTPS----MLQQDTNVTAGEVKESSAHGSSSKTSVDSQKKTDGSVTFSKFAEKHRRLLNSF-- 3272

  Fly   610 VGQE--------------------DNPRP----------------DLKLTVRRDQLINDALIGLE 638
            :.|.                    ||.:.                .|:::|||..::.|:   ..
plant  3273 IRQNPSLLEKSLSMMLKAPRLIDFDNKKAYFRSRIRHQHDQHISGPLRISVRRAYVLEDS---YN 3334

  Fly   639 MVAMSNPKDLKKQLVVEFVGEQGIDEGGVSKEFFQLIVEEIFNPAFGMFIQQEETNNMWFNATP- 702
            .:.|.:|:|||.:|.|:|.||:|||.||:::|::||:...||:.  |..:.....|:..|...|
plant  3335 QLRMRSPQDLKGRLNVQFQGEEGIDAGGLTREWYQLLSRVIFDK--GALLFTTVGNDATFQPNPN 3397

  Fly   703 ----FENGAQFTLIGIIIGLAIYNNVTLAVNFPMVVYRKLIGYCGTFADLSDWSPALYKSLKSML 763
                .|:.:.|..:|.::..|:::...|.|.|....|:.::|...|:.|:....|..||:||.:|
plant  3398 SVYQTEHLSYFKFVGRMVAKALFDGQLLDVYFTRSFYKHILGVKVTYHDIEAVDPDYYKNLKWLL 3462

  Fly   764 DYQGQDMEEVFEQTFK--------ISYSDVFGDVVQHELVPNGQDVLVGQHNKELFVNLYSDFLL 820
            :   .|:.::.:.||.        |.|...  :|..:||.|.|:::.|.:..|..:|:|.:..:|
plant  3463 E---NDVSDILDLTFSMDADEEKHILYEKT--EVTDYELKPGGRNIRVTEETKHEYVDLVAGHIL 3522

  Fly   821 NTNIEQQFNAFRKGF-EMVTDESPLKLLFRPEEIEMLVCGSREFDFVELENSTVYEGGYTEKSQY 884
            ...|..|.|||.:|| |::..|  |..:|..:|:|:|:.|..|.||.:|:.:|.|. .||..|..
plant  3523 TNAIRPQINAFLEGFNELIPRE--LVSIFNDKELELLISGLPEIDFDDLKANTEYT-SYTAGSPV 3584

  Fly   885 IQDFWSIVHAMPSEDKHKLLEFTTGSARVPVGGLKCL-------RLLITRHGPDSDRLPTSHTCF 942
            |..||.:|.|...||..:.|:|.||:::||:.|.|.|       ||.|.:.....:|||::||||
plant  3585 IHWFWEVVKAFSKEDMARFLQFVTGTSKVPLEGFKALQGISGPQRLQIHKAYGAPERLPSAHTCF 3649

  Fly   943 NVLLLPEYSSREKLEERLMKAIN-YSKGFG 971
            |.|.||||.|:|:|:|||:.||: .|:|||
plant  3650 NQLDLPEYQSKEQLQERLLLAIHEASEGFG 3679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ube3a	NP_648452.1	AZUL	40..94	CDD:465173	16/57 (28%)
		HECTc	620..971	CDD:238033	127/372 (34%)
UPL1	NP_001185245.1	DUF908	88..357	CDD:428721
		DUF913	418..763	CDD:461803
		UBA_atUPL1_2_like	1273..1310	CDD:270512
		UBM	2603..2631	CDD:464159	9/28 (32%)
		UBM	2641..2672	CDD:464159	4/30 (13%)
		HECTc	3319..3679	CDD:238033	127/372 (34%)