DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ube3a and Magi1

DIOPT Version :9

Sequence 1:NP_648452.1 Gene:Ube3a / 39266 FlyBaseID:FBgn0061469 Length:973 Species:Drosophila melanogaster
Sequence 2:XP_038964101.1 Gene:Magi1 / 500261 RGDID:1586025 Length:1491 Species:Rattus norvegicus


Alignment Length:359 Identity:77/359 - (21%)
Similarity:115/359 - (32%) Gaps:130/359 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 GGGEDDQ-----HLPGVSSA-------SGSAAGAVGGRATPEMKRSAVRSLIKRYFHQLQSGCGN 57
            ||.|..:     |:..:.:|       ||.....|.|  ||.:.:|  ..|:.:...|.      
  Rat   857 GGNEPGEPIYIGHIVPLGAADTDGRLRSGDELICVDG--TPVIGKS--HQLVVQLMQQA------ 911

  Fly    58 ANCSNANCASSGKV---APMTPNEVAARALQLFS--QDAQLCEAFTSEANSPQDVDMLSPNDSSS 117
            |...:.|.....||   .|...|||.:.|....|  |.|.|    |.|..:||            
  Rat   912 AKQGHVNLTVRRKVVFTVPKAENEVPSPASSHHSSNQPASL----TEEKRTPQ------------ 960

  Fly   118 SSSGSSTSTITSASTTTTTSRQSQSTPAAVVVPVSSPYLTQSVPQLDIAGAEHS-------SGDS 175
             .|.:|.:|::|.|.:|:.........:.||..|..||      .::|...|:.       |..|
  Rat   961 -GSQNSLNTVSSGSGSTSGIGSGGGGGSGVVSAVLQPY------DVEIRRGENEGFGFVIVSSVS 1018

  Fly   176 EPCTPTLAPVHSLDANSLIALYEQCRAADSYDRICHAIGVVF--SSVDRLGK------------- 225
            .|...|     :...|:.:|:             .|.||.:.  |..||.||             
  Rat  1019 RPEAGT-----TFAGNACVAM-------------PHKIGRIIEGSPADRCGKLKVGDRILAVNGC 1065

  Fly   226 -----------SFIRSAE--------PAASSSLQELLANSPGALNKEQLRTLEGEHDKDEDSTQQ 271
                       :.|:.|.        |...||...||.|:      |::.|:...|...:..||:
  Rat  1066 SITNKSHSDIVNLIKEAGNTVTLRIIPGDESSNATLLTNA------EKIATITTTHAPSQQGTQE 1124

  Fly   272 VDEQSESAANATATAESVESEAE------PEEED 299
                     ..|.|....:|:.|      .:|:|
  Rat  1125 ---------TRTTTKPKPDSQFEFKGPQATQEQD 1149

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ube3aNP_648452.1 AZUL 40..94 CDD:293166 14/58 (24%)
HECTc 620..971 CDD:238033
HECTc 647..970 CDD:214523
Magi1XP_038964101.1 NK 122..293 CDD:418433
WW 302..331 CDD:395320
WW 362..393 CDD:197736
PDZ 469..555 CDD:214570
PDZ 640..723 CDD:214570
MAGI_u5 724..806 CDD:406953
PDZ_signaling 847..922 CDD:238492 16/74 (22%)
PDZ_signaling 996..1091 CDD:238492 20/118 (17%)
PDZ 1152..1234 CDD:214570
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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