Protein Alignment Ube3a and CG42797

DIOPT Version :9

• Sequence 1: NP_648452.1
• Gene: Ube3a / 39266
• FlyBaseID: FBgn0061469
• Length: 973
• Species: Drosophila melanogaster
• Sequence 2: NP_572574.2
• Gene: CG42797 / 31905
• FlyBaseID: FBgn0261931
• Length: 1426
• Species: Drosophila melanogaster
• Alignment Length: 1276
• Identity: 264/1276 - (20%)
• Similarity: 433/1276 - (33%)
• Gaps: 419/1276 - (32%)

  Fly     8 EDDQHLPGVSSASGSAAGAVGG----------------RATPEMKRSAVRS-------------- 42
            |:|:....|.|..|:||.....                :.:|...|...||
  Fly   258 EEDEEAAAVESLLGAAAALQASAHVQRRQQQQHHQHLRQPSPPQHRPLERSWPPRAVGRDLKLQG 322

  Fly    43 ---------LIKRYFHQLQSGCGNAN---------------------CSNANCASSGKVA----- 72
                     ..:|...::..|.|::|                     .|..|..|:.||.
  Fly   323 DVFQFDILDTDERLAEEMAQGSGSSNNSPLATPPVRFKPLLKKKIGPDSYINTISTQKVPVHQSY 387

  Fly    73 --PMTPNEVAA-------RALQL--FSQDAQLCEAFTS-EANSPQDVD----MLSPNDSSSSSSG 121
              |..|:..|.       .:||.  ..|...|..|.:: :|:|.::..    :|||....|..||
  Fly   388 EFPTFPSSSAVGSSSSSPNSLQFPYLRQHRPLTRALSNGKASSSEEQASPRLLLSPKRPRSPPSG 452

  Fly   122 SSTSTITSASTTTTTSRQSQSTPAAV------VVPVSSPYLTQSVPQLDI-------AGAEHSSG 173
            .||.:.:....:.:..:.|.:....|      .||..:|......||..:       |||..:.|
  Fly   453 CSTRSASPLDISLSPEQHSPTRGRGVGGALQDAVPPGTPTFHGQRPQQRLLKRVGGGAGAGATGG 517

  Fly   174 -DSEP--CTPTLAPVH---------SLDANSLIALYEQCRAADSYDRICHAIGVVFSSVDRLGKS 226
             ...|  |.||  |.|         ::.|||.:|                            ...
  Fly   518 ATGSPLVCPPT--PTHHARRHARLQAVTANSSLA----------------------------SGG 552

  Fly   227 FIRSAEPAASSSLQELLANSPGALNKEQLRTLEGEHDKDE----DSTQ--QVDEQSESAANATAT 285
            .|.|..||.||.|..:.....|   :||     |:...||    .||:  .:.|:|.:||.|.|.
  Fly   553 AIPSDPPAVSSQLDYIYLQDGG---QEQ-----GQEQSDEVVHISSTRLPSIPERSAAAAAAAAA 609

  Fly   286 AESVESEAEP-----------------------EEEDDD-----VCSSQSSDTLVDLPGL----- 317
            |.:..:..||                       |...|.     .....:..|....||.
  Fly   610 AAAGAALMEPGTGTVSGSSGAGAAGEPPLPPAWEARMDSHGRIFYIDHTTRTTSWQRPGAAPSGG 674

  Fly   318 -------------RRVQRLLFGCQIRAITEKLTSSVIQLSDWVIYMRTDWERVIHCLVICFDLAT 369
                         ||.|.:.     |.||.:  |...||                     ::|.|
  Fly   675 PAGREQHHRQQLDRRYQSIR-----RTITNE--SRAAQL---------------------YNLPT 711

  Fly   370 NTNNSVVDMDYLDRVLPKLCQAASAMPVPAQARLARIWAAHCSDQLHSLI------------AAC 422
            :.|::.             ...|.|.|.||.|....|... |....:||:            .|.
  Fly   712 SANSNA-------------NSTAPAAPPPATAIHPAILML-CRPDFYSLLHTNEAALAIYNRNAA 762

  Fly   423 QQQITLQVLLDE---ESMRENESIISVTKVLKIVFYANILASELERPSCRVPLEDRTEAATASGS 484
            .:.:.:::..|.   :..:.|:.::::...     :|.:   ..|.|||.....|:      ||.
  Fly   763 LKHMVMRIRRDPPCFQRYQYNKDLVALVNT-----FAQM---SRELPSCWETKLDQ------SGK 813

  Fly   485 AAVEDDLFVYNSLLEPHMP-------KFAEDQFEKELQV-------------------------S 517
            ....|......|.::|.:|       :..:...:::..|                         |
  Fly   814 QFFIDHQHRRTSFMDPRLPVECPRVVRHRQQHSQQQSSVGYYYPDLVDGNCLSATSGHINASPAS 878

  Fly   518 AIDCRKPLIPLEEFYNEALSENIQMH-H--------------DYLSYKTLAMESEIGSGHANY-- 565
            ::....||.|.....:.:.|.:...| |              |..:|....|.| .|:..|.|
  Fly   879 SVSGVPPLPPPRPSSSSSSSRSSHGHGHNCNTTSAISCALNADRSAYGAAGMAS-AGATAAGYED 942

  Fly   566 ----FSFMLYAFILTPS-------------------TKVDAL----------------------- 584
                ::..:.||:..|:                   .|::.|
  Fly   943 VPIAYNEKVIAFLRQPNILEILRERQGQHTMSRQLREKINILRVEGVPALERLGHDLQLTILLSL 1007

  Fly   585 --------------------YYDSRMRMYS------ERYSSLHSILNNIGQVGQEDNPRPDLKLT 623
                                ..:|||...:      :..:.|.|....:...|....|. .|||.
  Fly  1008 FEQEIMGFVPIEERSPQGSPVLNSRMPQRAPPPFRRDFEAKLRSFYRKLESKGYGQGPH-KLKLH 1071

  Fly   624 VRRDQLINDALIGLEMVAMSNPKDLKK-QLVVEFVGEQGIDEGGVSKEFFQLIVEEIFNPAFGMF 687
            :||..|:.||   ...:..:|.|||:: :|.|.:..|:|:|.||.|:|||.|:..|:|||.:|:|
  Fly  1072 IRRSHLLEDA---FRRIMSANKKDLQRGRLAVLWDTEEGLDYGGPSREFFFLLSRELFNPYYGLF 1133

  Fly   688 IQQEETNNMWFNATP---FENGAQ--FTLIGIIIGLAIYNNVTLAVNFPMVVYRKLIGYCGTFAD 747
             :....:......:|   |.:...  |...|.::|||:.:...|...|....|:.|:......:|
  Fly  1134 -EYSANDTYTVQVSPLSAFVDNCHDWFRFSGRVLGLALVHQYLLDAFFTRPFYKALLRLPVALSD 1197

  Fly   748 LSDWSPALYKSLKSMLDYQ---GQDMEEVFEQTFKISYSDVFGDVVQHELVPNGQDVLVGQHNKE 809
            |.......::||:.:.|..   |.|:...|..|     .::.|.||..||.|.|:::::.:.||:
  Fly  1198 LESLDNEFHQSLQWIRDNDIGTGVDLGLTFCVT-----EELLGSVVDRELKPGGKNIIINEKNKK 1257

  Fly   810 LFVNLYSDFLLNTNIEQQFNAFRKGFEMVTDESPLKLLFRPEEIEMLVCGSREFDFVELENSTVY 874
            .::.....:.|...:::|..:..:||..|.| |.|..:|...|:|:::.|:.|.|..:...:|.|
  Fly  1258 EYLERMIKWRLERGVQEQTESLVRGFYEVID-SRLVSVFDARELELVIAGTAEIDTNDWRLNTEY 1321

  Fly   875 EGGYTEKSQYIQDFWSIVHAMPSEDKHKLLEFTTGSARVPVGGLKCL-------RLLITRHG-PD 931
            ..||.:..|.|..||.::....:|.:.:||:|.||::.:|..|...|       |..|.:.| |:
  Fly  1322 RSGYHDNHQVIVWFWQVIERFSNEQRLRLLQFVTGTSSIPYEGFSALRGSTGPRRFCIEKWGKPN 1386

  Fly   932 SDRLPTSHTCFNVLLLPEYSSREKLEERLMKAINYSKGFGM 972
            :  ||.:|||||.|.||.|.:.|.|.|:|:.|:..:..||:
  Fly  1387 A--LPRAHTCFNRLDLPPYPTPELLYEKLLLAVEETNTFGI 1425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ube3a	NP_648452.1	AZUL	40..94	CDD:293166	17/113 (15%)
		HECTc	620..971	CDD:238033	110/367 (30%)
		HECTc	647..970	CDD:214523	100/339 (29%)
CG42797	NP_572574.2	WW	638..667	CDD:278809	3/28 (11%)
		HECTc	1068..1424	CDD:238033	110/367 (30%)
		HECTc	1092..1423	CDD:214523	100/339 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446969
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740