Protein Alignment Ube3a and Plekha7

DIOPT Version :9

• Sequence 1: NP_648452.1
• Gene: Ube3a / 39266
• FlyBaseID: FBgn0061469
• Length: 973
• Species: Drosophila melanogaster
• Sequence 2: XP_017177675.1
• Gene: Plekha7 / 233765
• MGIID: 2445094
• Length: 1359
• Species: Mus musculus
• Alignment Length: 596
• Identity: 119/596 - (19%)
• Similarity: 190/596 - (31%)
• Gaps: 189/596 - (31%)

  Fly    13 LPGVSSASGSAAGAVGGRATPEMKRSAVRSLIKRYFHQLQSGCGNANCSNANCASSGKVAPMTPN 77
            |||         |..|.:|.|:   .|.::.:..|      |.|..|.:|    ...:.||...|
Mouse   376 LPG---------GPRGQQAQPQ---RAEKNGVPPY------GLGEQNGTN----GYQRTAPPRAN 418

  Fly    78 EVAARALQLFSQDAQLCEAFTSEANSPQDVDMLSPNDSSSSSSGSSTSTITSASTTTTTSRQSQS 142
                                 .|.:|.:...:......:.:..|..    .|.....|..||..|
Mouse   419 ---------------------PEKHSQRKTGLAQAEHWTKAQKGDG----RSLPLDQTLPRQGPS 458

  Fly   143 TPAAVVVPVSSPYLTQSVPQLDIAGAEHSSGDSEPCTPTLAPVHSLDANSLIALYEQCRAA---- 203
            .      |:|.|...||:|:    ...|.||.|.|      |..:|.::   ..|.|.||:
Mouse   459 Q------PLSFPENYQSLPK----STRHLSGSSSP------PPRNLPSD---YKYAQDRASHLKM 504

  Fly   204 DSYDRICHAIGVVFSSVDRLGKSFIRSAEPAASSSLQELLANSPGALNKEQLRTL---------- 258
            .|.:|..|..|.|:...:...:...|...|.|     .:.|.||....:.:.|:|
Mouse   505 SSEERRAHRDGTVWQLYEWQQRQQFRHGSPTA-----PIGAGSPEFTEQGRSRSLLEVPRSISVP 564

  Fly   259 -----------------EGEHDKDEDSTQQVDEQSESA------------ANATATAESVESEAE 294
                             ...|...|..|.:..||..|.            .:|...:..|:..:.
Mouse   565 PSPSDIPPPGPPRPFPPRRPHTPAERVTVKPPEQRRSVDISLGGSPRKARGHAAKNSSHVDRRSM 629

  Fly   295 PE-------EEDDDVCSSQSSDTLVDLPGLRRVQRLLFGCQIRAITE----KLTSSVIQLSDWVI 348
            |.       .....:......:..:.|..|:|.|..|...:..|:.:    .||....|..|..:
Mouse   630 PSMGYMTHTVSAPSLHGKSLEELSLLLTRLQRHQSKLASVRNFAVGQLLHHYLTFPACQADDTYL 694

  Fly   349 YMRTDWERVIHCLVICFDLATNTNNSVVDMDYLDRVLPK---------------LCQAASAMPVP 398
            .::.|.|.:        ||....|..::::.|  :||.|               |.:..|..|:
Mouse   695 QLKKDLEYL--------DLKIKNNEPLINVLY--KVLKKSARGCRPGRSMTGRDLLKDRSLKPM- 748

  Fly   399 AQARLARIWAAHCSDQLHSLIAACQQQITLQVLLDE-ESMREN-ESIISVTKVL----------- 450
               ::|.      ||....|...|:|...||.|.|: .:::|| :.:.||.:||
Mouse   749 ---KIAE------SDIDVKLSIFCEQDRILQDLEDKIRALKENKDQLESVLEVLHRQTEQYRDQP 804

  Fly   451 ----KIVFYANILASEL---ERPSCRVPLEDRTEAATA-SGSAAVEDDL-FVYNSLLEPHMPKF- 505
                ||.....:|..:|   ....||    :.||...| :....:|.|: .:..:|.|.|...|
Mouse   805 QHLEKITCQQRLLQEDLVHIRAELCR----ESTEMENAWNEYLKLEKDVEQLKQTLQEQHRRAFF 865

  Fly   506 --AEDQFEKEL 514
              .:.|.:|:|
Mouse   866 FQEKSQIQKDL 876

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ube3a	NP_648452.1	AZUL	40..94	CDD:293166	8/53 (15%)
		HECTc	620..971	CDD:238033
		HECTc	647..970	CDD:214523
Plekha7	XP_017177675.1	WW	10..39	CDD:366073
		WW	55..84	CDD:366073
		PH_PEPP1_2_3	158..280	CDD:270068
		Smc	<692..>894	CDD:224117	46/209 (22%)
		PHA03247	<903..1009	CDD:223021
		PRK10263	<912..>1118	CDD:236669

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900