DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ube3a and Magi1

DIOPT Version :9

Sequence 1:NP_648452.1 Gene:Ube3a / 39266 FlyBaseID:FBgn0061469 Length:973 Species:Drosophila melanogaster
Sequence 2:XP_006505643.1 Gene:Magi1 / 14924 MGIID:1203522 Length:1484 Species:Mus musculus


Alignment Length:361 Identity:77/361 - (21%)
Similarity:123/361 - (34%) Gaps:116/361 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 GGEDDQHLPGVSS-ASGSAAGAVGGRATPEMKR-------------------------------- 37
            ||.:....|.|.: |:..|||..||...|::..                                
Mouse    34 GGAEHGEFPYVGAVAAAEAAGLPGGGEGPKLAEGELLLEVQGVRVSGLPRYDVLGVIDSCKEAVT 98

  Fly    38 -SAVRS---LIK--RYF-----------HQLQSGCGN------ANCSNANCASSGKVAPMTPNEV 79
             .|||.   |.|  |:|           |:||....:      ..|:..: ...|:|..:..:.:
Mouse    99 FKAVRQGGRLNKDLRHFLNQRFQKGSPDHELQQTIRDNLYRHAVPCTTRS-PREGEVPGVDYSFL 162

  Fly    80 AARALQLFSQDAQLCEAFTSEANSPQDVDMLSPNDSSSSSSGSSTSTITSASTTTTTSRQSQSTP 144
            ..:......|...|.|..|.|.|.     ..:|...|...||   ..||:.:..:..|...||||
Mouse   163 TVKEFLDLEQSGTLLEVGTYEGNY-----YGTPKPPSQPVSG---KVITTDALHSLQSGSKQSTP 219

  Fly   145 -----------AAVVVPVSSPYLTQSVPQLDIAGAEHSSGDSEPCT---PTLAPVHSLDANSLIA 195
                       |.:|.|.:..  .:.||::: :.....|||.:..|   .||.||:|    |::|
Mouse   220 KRTKSYNDMQNAGIVHPENEE--EEDVPEMN-SSFTADSGDQDEHTLQEATLPPVNS----SILA 277

  Fly   196 --LYEQCRAADSYDRICHAIGVVFSSVDRLG-------KSFIRSAE-------PAASSSLQELLA 244
              :.:..:....|        :..|:.|.||       .::..:.|       ...:|.|     
Mouse   278 APITDPSQKFPQY--------LPLSAEDNLGPLPENWEMAYTENGEVYFIDHNTKTTSWL----- 329

  Fly   245 NSPGALNKEQLRTLEGEHDKDEDSTQQVDEQSESAA 280
             .|..|||:|....|.|.|::...|:::|.:.|..|
Mouse   330 -DPRCLNKQQKPLEECEDDEEGVHTEELDSELELPA 364

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ube3aNP_648452.1 AZUL 40..94 CDD:293166 13/75 (17%)
HECTc 620..971 CDD:238033
HECTc 647..970 CDD:214523
Magi1XP_006505643.1 PDZ_signaling 15..100 CDD:238492 11/65 (17%)
GuKc 122..293 CDD:214504 40/194 (21%)
WW 302..331 CDD:366073 3/34 (9%)
WW 362..393 CDD:197736 1/3 (33%)
PDZ 462..548 CDD:214570
PDZ 633..716 CDD:214570
MAGI_u5 715..798 CDD:374709
PDZ_signaling 840..915 CDD:238492
PDZ_signaling 989..1084 CDD:238492
PDZ 1145..1227 CDD:214570
PRK12678 1203..>1452 CDD:237171
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5021
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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