Protein Alignment Ube3a and herc3

DIOPT Version :9

• Sequence 1: NP_648452.1
• Gene: Ube3a / 39266
• FlyBaseID: FBgn0061469
• Length: 973
• Species: Drosophila melanogaster
• Sequence 2: XP_002938676.3
• Gene: herc3 / 100488790
• XenbaseID: XB-GENE-968537
• Length: 1050
• Species: Xenopus tropicalis
• Alignment Length: 1092
• Identity: 268/1092 - (24%)
• Similarity: 440/1092 - (40%)
• Gaps: 275/1092 - (25%)

  Fly     5 GGGEDDQHLPGVSSASGSAAGAVGGRATPEMKRSAVRSLIKRYFHQ--LQSGCGNANCSNANCAS 67
            |.|.|.|.                |.||.| ..|.:..:||:...|  .|..|||.:|
 Frog   109 GSGNDGQL----------------GHATVE-HSSRIPRIIKKLNQQKIQQVSCGNDHC------- 149

  Fly    68 SGKVAPMTPNEVAARAL----QLFSQDAQ------LCEAFTSEANSPQDVDMLSPNDSSSSSSGS 122
                          .||    |||:....      |...|.|: :|||.|..|.....:..::|.
 Frog   150 --------------MALGDDGQLFTWGQNLHGQLGLGNGFLSQ-SSPQRVKSLEGIPLAQVTAGG 199

  Fly   123 STSTI------------TSASTTTTTSRQSQSTPAAVVVPVSSPYLTQSVPQLDIAGAEHS---- 171
            |.|..            .||........:.:.||..|     .|..|..|..:. .|.||:
 Frog   200 SHSFALSLSGAVFGWGNNSAGQLGLNDEKVRETPCHV-----KPLRTHKVIYIS-CGEEHTAILT 258

  Fly   172 ------------SGD--------------------SE---------------PCTPTLAPVHSLD 189
                        ||.                    ||               |.:.||......|
 Frog   259 KAGGLFTFGAGGSGQLGHDSLNNEINPRRVLELMGSEVSQIACGRQHTLAFVPSSGTLYAFGCGD 323

  Fly   190 ANSL----------IALYEQCRAADSYDRICHAIGVVFSSVDRL----GKSFIRSAEPAASSSLQ 240
            ...|          .|:.:...||.|.....||....::.|.::    .|:|:..::..:|....
 Frog   324 LGQLGTGHKNNVKCPAVVKGKWAAHSGQISMHADRAAYNIVKQIFSGGNKTFVLCSKLESSQPAD 388

  Fly   241 EL----LANSPGALNKEQL-----RTLEGEHDKDEDSTQQVDEQSESAANATATAESVESEAEPE 296
            :.    ..|....:|:|.:     :.||..:....:...|           |.::.:..:.:..|
 Frog   389 DFRFCSQRNHTSVINEETIDVWRQKVLENSNTNSMNGIVQ-----------TLSSLACWNGSFLE 442

  Fly   297 EEDDDVCSSQSSDTLVDLPGLRRVQRLLFGCQIRAITEKLTSSVIQLSDWVIYMRTDWERVIHCL 361
            :.:|     :...|...:||:..       |.|:.:.|||             |.....|::..:
 Frog   443 KRND-----EHFRTSPKIPGINM-------CSIKVLFEKL-------------MNVHHSRLLEQI 482

  Fly   362 VICFD--LATNTNNSVVDMD----YLDRVLPK--LCQAAS---AMPVPAQARLARI--------- 406
            :..|:  |....::|..|::    |:  :||:  |.|.:.   .:.:|....:.|:
 Frog   483 LKGFESFLIPQLSSSPPDVEAMRIYI--ILPEFPLLQDSKYYITLTLPLAMAILRLDTNPSKVLD 545

  Fly   407 --WAAHCSDQLHSLIAACQQQITLQVLLDEESMRENESIISVTKVLKIVFYANILASELERPSCR 469
              ||..|......||:..::.:.  .||:...          |.::.::|.:.|.|:
 Frog   546 NWWAQVCPKYFLKLISLYKEAVV--YLLNGRK----------TLLIPVLFTSYITAA-------- 590

  Fly   470 VPLEDRTEAATASGSAA-VEDDLFVYNSLLEPHMPKFAEDQFEKELQVSAIDCRKPLIPLEEFYN 533
              |:...:....:|.|. ||.|.|        ::|:.:          |.:|.::..  |..|.|
 Frog   591 --LKLLEKLHKVNGKAQHVEHDTF--------YIPEIS----------SLVDIQEDY--LMWFLN 633

  Fly   534 EALSENIQMHHDYLSYKTLAMESEIGSGHANYFSFMLYAFILTPSTKVDALYYDSRMRMYSERYS 598
            ||          .|..:...|:..|        :...|.|:.....|...|..|:.::|   :.:
 Frog   634 EA----------GLKLRPTIMQDSI--------TLCSYPFVFDAQAKTKMLQTDAELQM---QVA 677

  Fly   599 SLHSILNNIGQVGQEDN---PRPDLKLTVRRDQLINDALIGLEMVAMSNPKDLKKQLVVEFVGEQ 660
            ...:.|.|:..:...|.   ..|.|.|.|||..|:.||   |..:::.:..||||.|.|.|.||:
 Frog   678 INGANLQNVFMLLTLDPMLVKNPFLVLHVRRTSLVADA---LRELSIYSDIDLKKPLKVIFDGEE 739

  Fly   661 GIDEGGVSKEFFQLIVEEIFNPAFGMFIQQEETNNMWFNATPFENGAQFTLIGIIIGLAIYNNVT 725
            .:|:|||:||||.|:::|:.||.:|||...:::|.:||:...|.....|.||||:.||||||...
 Frog   740 AVDDGGVTKEFFLLLLKELLNPIYGMFTVYQDSNLLWFSDICFVEHNWFHLIGIMCGLAIYNFTV 804

  Fly   726 LAVNFPMVVYRKLIGYCGTFADLSDWSPALYKSLKSMLDYQGQDMEEVFEQTFKISYSDVFGDVV 790
            :.:.||:.:|:||:....|..||.:.||...:||:.:|||...|:::||...|.|. .:.:|...
 Frog   805 VDLYFPLALYKKLLNVQPTLEDLKELSPTEGRSLQELLDYPEDDVDDVFCLNFTIC-RESYGLAE 868

  Fly   791 QHELVPNGQDVLVGQHNKELFVNLYSDFLLNTNIEQQFNAFRKGFEMVTDESPLKLLFRPEEIEM 855
            :..||..|..:.|.:.|::.||:.|.:::.|.::::.:.||..||..|.....|: ||:|.|:..
 Frog   869 RRPLVAGGDHITVTKDNRQQFVDAYVNYVFNQSVQEWYEAFSTGFLKVCGGKILE-LFQPSELRS 932

  Fly   856 LVCGSREFDFVELENSTVYEGGYTEKSQYIQDFWSIVHAMPSEDKHKLLEFTTGSARVPVGGLKC 920
            :|.||..:::.|||.:.:|:|.|:.....::.||...|..|.|.|.|.|.|.|||.|:|:.|:..
 Frog   933 MVVGSNNYNWQELEENAIYKGDYSTAHPTVRMFWETFHDFPLEKKKKFLLFLTGSDRIPIYGMSS 997

  Fly   921 LRLLITRHGPDSDRLPTSHTCFNVLLLPEYSSREKLEERLMKAINYSKGFGM 972
            ||::|.......|.||.:|||:|:|.||:|||:|.|..||.:||::.:||.:
 Frog   998 LRIIIQSISSGEDHLPVAHTCYNLLDLPKYSSKETLRRRLTQAIDHYEGFSL 1049

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ube3a	NP_648452.1	AZUL	40..94	CDD:293166	13/65 (20%)
		HECTc	620..971	CDD:238033	135/350 (39%)
		HECTc	647..970	CDD:214523	125/322 (39%)
herc3	XP_002938676.3	RCC1	3..49	CDD:395335
		ATS1	44..353	CDD:227511	57/288 (20%)
		HECTc	702..1048	CDD:238033	135/350 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276447at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920