Protein Alignment Plod and Plod

DIOPT Version :10

• Sequence 1: NP_648451.1
• Gene: Plod / 39265
• FlyBaseID: FBgn0036147
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: XP_321614.5
• Gene: Plod / 1281666
• VectorBaseID: AGAMI1_004093
• Length: 727
• Species: Anopheles gambiae
• Alignment Length: 692
• Identity: 373/692 - (53%)
• Similarity: 505/692 - (72%)
• Gaps: 1/692 - (0%)

  Fly    31 VFTVATEPTDGYTRYIRSARVYDIEVTTLGLGEEWKGGDMQKPGGGFKLNLLREAIAPYKNEPET 95
            :||||:..|:||.||:|||:.||:.|||||:|:.|.||:|:..|||:|:||||||:.||:.:.:.
Mosquito    36 IFTVASNATEGYVRYLRSAKHYDLTVTTLGMGKPWLGGNMKSVGGGYKINLLREALKPYRADKDR 100

  Fly    96 IILFTDSYDVIITTTLDEIFEKFKESGAKILFSAEKYCWPDKSLANDYPEVEGKASRFLNSGAFI 160
            ::||||||||:......:|.|||....|.|:|.||.:||||:||.:.||.:||:..|:||||.|:
Mosquito   101 LVLFTDSYDVLFLAPWAKIQEKFASFEASIVFGAEGFCWPDESLKSAYPPLEGRGMRYLNSGLFM 165

  Fly   161 GYAPQVFALLVDPIEDTADDQLYFTKIFLDETKRAKLGLKLDVQSRLFQNLHGAKNDVKLKVDLE 225
            |||.:::.||..|::|..|||||:||.:|||..|.:|.:|||..:.|||||:|.:..|.|.::..
Mosquito   166 GYADKLYKLLKTPVKDAEDDQLYYTKAYLDEELRQELNIKLDHMATLFQNLNGVEEQVVLSLEPS 230

  Fly   226 SNQGVLQNVDFMTTPSIIHGNGLSKVDLNAYGNYLARTF-NGVCLLCQENLLDLEETNLPVISLA 289
            ..:..|.|.::.|.|:|:||||.||:.||:|.||||..| :|.|...:|..|.|.:..||::::|
Mosquito   231 EKEATLANSEYNTKPAIVHGNGPSKLTLNSYANYLAGAFVDGECQTVKEGRLTLSDGELPLVTMA 295

  Fly   290 LMVTQPVPFFDQFLEGIESLNYPKEKLHLLIYSNVAFHDDDIKSFVNKHAKEYATAKFALSTDEL 354
            |.|.:|.||.:::...|..||||.::|.:|::||||:|...:|:|::.....|.:.|......:.
Mosquito   296 LFVEKPTPFLEEWFGTIAKLNYPADRLDVLVHSNVAYHAGTVKAFLDAQEGRYRSLKVIEHDGDF 360

  Fly   355 DERQGRQLALDKARLHQSDYIFFVDADAHIDDGEVLRELLRLNKQFVAPIFSKHKELWSNFWGAL 419
            .|...|..|.....|...||:|.||::..:||..|||.|:..|:..:||:.::.:::||||||||
Mosquito   361 TETAARNFATKHCELRGCDYLFVVDSEGRLDDPNVLRALIEANRNVIAPVLTRPEKVWSNFWGAL 425

  Fly   420 SEGGYYARSHDYVDIVKRELIGMFNVPHVTSIYLVKKTAFDAISFKHKEFDPDMAMCESLRNAGI 484
            |..|:||||:||:|||.|:|:|::|||.|:.:||||:.....:|::.:|.|||||:|...|:.||
Mosquito   426 SGQGFYARSNDYMDIVGRKLLGLWNVPFVSIVYLVKRAVLPEVSYELQETDPDMALCWHFRSKGI 490

  Fly   485 FMYASNLRIFGHLVNADDFNTTVTRPDFYTLFSNEIDWTEKYIHPNYSLQLNESNKIQQPCPDVY 549
            ||:..|:..:|||::.:.|:.|.|.||||.||:|..||.::|:...|..||......||||||||
Mosquito   491 FMHVINVEQYGHLIDTEYFDMTRTHPDFYQLFNNRHDWEQRYLAHGYKQQLEADFVPQQPCPDVY 555

  Fly   550 WFQIVSDAFCDDLVAIMEAHNGWSDGSNNDNRLEGGYEAVPTRDIHMKQVGLERLYLKFLQMFVR 614
            ||.|.||.|||||..|:||...|||||::|.||:|||||||||||||.|||||:|:|||||::||
Mosquito   556 WFAIGSDRFCDDLREIVEAFGEWSDGSHSDKRLQGGYEAVPTRDIHMNQVGLEQLWLKFLQLYVR 620

  Fly   615 PLQERAFTGYFHNPPRALMNFMVRYRPDEQPSLRPHHDSSTYTINIAMNRAGIDYQGGGCRFIRY 679
            ||||:.|.||||:|||:||||:|||||||||||||||||||||||||:|.||:||:||||||:||
Mosquito   621 PLQEKVFIGYFHDPPRSLMNFVVRYRPDEQPSLRPHHDSSTYTINIALNTAGVDYEGGGCRFLRY 685

  Fly   680 NCSVTDTKKGWMLMHPGRLTHYHEGLLVTNGTRYIMISFIDP 721
            |||||||:|||||:|||||||:|||||.|.|||||||||:||
Mosquito   686 NCSVTDTRKGWMLLHPGRLTHFHEGLLTTKGTRYIMISFVDP 727

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Plod	NP_648451.1	GT_LH	27..257	CDD:459235	112/225 (50%)
		Glyco_tranf_GTA_type	303..>395	CDD:472172	31/91 (34%)
		P4Hc	555..719	CDD:214780	131/163 (80%)
Plod	XP_321614.5	None