Protein Alignment Plod and Plod1

DIOPT Version :10

• Sequence 1: NP_648451.1
• Gene: Plod / 39265
• FlyBaseID: FBgn0036147
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_446279.2
• Gene: Plod1 / 116552
• RGDID: 621382
• Length: 728
• Species: Rattus norvegicus
• Alignment Length: 733
• Identity: 324/733 - (44%)
• Similarity: 467/733 - (63%)
• Gaps: 22/733 - (3%)

  Fly     5 QSALLLLLLA--VTSQGDAESNWNDKIKVFTVATEPTDGYTRYIRSARVYDIEVTTLGLGEEWK- 66
            :|.|||..||  :.:|...::...|.:.|.||||:.|:|:.|:.|||:.::.::.:|||||:|.
  Rat     2 RSLLLLASLAWLLLAQAKDDAKLEDNLLVLTVATKETEGFRRFKRSAQFFNYKIQSLGLGEDWSA 66

  Fly    67 GGDMQKPGGGFKLNLLREAIAPYKNEPETIILFTDSYDVIITTTLDEIFEKFKESGAKILFSAEK 131
            .|.....|||.|:.||::|:..|.::.:.:|||.|||||:..:...|:.:||:::.::::||||:
  Rat    67 AGGPSAAGGGQKVRLLKKALKKYADKEDLVILFVDSYDVVFASGPRELLKKFQQAKSRVVFSAEE 131

  Fly   132 YCWPDKSLANDYPEV-EGKASRFLNSGAFIGYAPQVFALLVD-PIEDTADDQLYFTKIFLDETKR 194
            ..:||:.|...||.| :||  |||.||.||||||.:..|:.: ..:|...|||::||||||..||
  Rat   132 LIYPDRRLEAKYPTVPDGK--RFLGSGGFIGYAPSLSKLVAEWEGQDNDSDQLFYTKIFLDPEKR 194

  Fly   195 AKLGLKLDVQSRLFQNLHGAKNDVKLKVDLESNQGVLQNVDFMTTPSIIHGNGLSKVDLNAYGNY 259
            .::.:.||.:.|:||||.||.::|.||.::...:.  :|:.:.|.|.:|||||.:|:.:|..|||
  Rat   195 EQINISLDHRCRIFQNLDGALDEVVLKFEMGHVRA--RNLAYDTLPVVIHGNGPTKLQVNYLGNY 257

  Fly   260 LAR--TFNGVCLLCQENLLDLE---ETNLPVISLALMVTQPVPFFDQFLEGIESLNYPKEKLHLL 319
            :.|  ||...|.:|.|.|..|:   :..||.:.:.:.:.||.||...|...:..|.||::::.|.
  Rat   258 IPRFWTFETGCTVCDEGLRSLKGIGDEALPTVLVGVFIEQPTPFLSLFFRRLLHLRYPQKQMRLF 322

  Fly   320 IYSNVAFHDDDIKSFVNKHAKEYATAKFALSTDELDERQGRQLALDKARLHQS-DYIFFVDADAH 383
            |::....|...::.|:.:|..||.:.|.......:.....|.:..|..|..|: .|.|.||||..
  Rat   323 IHNQEQHHKLQVEQFLAEHGGEYQSVKLVGPEVRMANADARNMGADLCRQDQTCTYYFSVDADVA 387

  Fly   384 IDDGEVLRELLRLNKQFVAPIFSKHKELWSNFWGALSEGGYYARSHDYVDIVKRELIGMFNVPHV 448
            :.:...||.|:..||..:||:.::|..||||||||||..||||||.||||||:...:|::|||::
  Rat   388 LTEPNSLRLLIEQNKNVIAPLMTRHGRLWSNFWGALSADGYYARSEDYVDIVQGRRVGVWNVPYI 452

  Fly   449 TSIYLVKKTAFDA-----ISFKHKEFDPDMAMCESLRNAGIFMYASNLRIFGHLVNADDFNTTVT 508
            ::|||:|.:|..|     ..|.:.:.||||:.|.::|...:||:.:|...||||::.|::.||..
  Rat   453 SNIYLIKGSALRAELRHVDLFHYSKLDPDMSFCANVRQQEVFMFLTNRHTFGHLLSLDNYQTTHL 517

  Fly   509 RPDFYTLFSNEIDWTEKYIHPNYSLQLNESNKIQQPCPDVYWFQIVSDAFCDDLVAIMEAHNGWS 573
            ..|.:.:|||..||.|||||.||:..| ....::.||||||||.|.::..||:||..||.:..||
  Rat   518 HNDLWEVFSNPEDWKEKYIHENYTKAL-AGKLVETPCPDVYWFPIFTEVACDELVEEMEHYGQWS 581

  Fly   574 DGSNNDNRLEGGYEAVPTRDIHMKQVGLERLYLKFLQMFVRPLQERAFTGYFHNPPRALMNFMVR 638
            .|.|.|||::||||.|||.||||.|:..||.:.|||..::.||.|:.:.||:......|. |:||
  Rat   582 LGDNKDNRIQGGYENVPTIDIHMNQITFEREWHKFLVEYIAPLTEKLYPGYYTKAQFDLA-FVVR 645

  Fly   639 YRPDEQPSLRPHHDSSTYTINIAMNRAGIDYQGGGCRFIRYNCSVTDTKKGWMLMHPGRLTHYHE 703
            |:|||||||.||||:||:|||||:||.|.||:||||||:||||||...:|||.||||||||||||
  Rat   646 YKPDEQPSLMPHHDASTFTINIALNRVGEDYEGGGCRFLRYNCSVRAPRKGWALMHPGRLTHYHE 710

  Fly   704 GLLVTNGTRYIMISFIDP 721
            ||..|.|||||.:||:||
  Rat   711 GLPTTKGTRYIAVSFVDP 728

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Plod	NP_648451.1	GT_LH	27..257	CDD:459235	96/232 (41%)
		Glyco_tranf_GTA_type	303..>395	CDD:472172	24/92 (26%)
		P4Hc	555..719	CDD:214780	99/163 (61%)
Plod1	NP_446279.2	GT_LH1	26..255	CDD:438560	96/232 (41%)
		P4Hc	563..726	CDD:214780	99/163 (61%)