Protein Alignment Plod and plod2

DIOPT Version :10

• Sequence 1: NP_648451.1
• Gene: Plod / 39265
• FlyBaseID: FBgn0036147
• Length: 721
• Species: Drosophila melanogaster
• Sequence 2: NP_001082933.1
• Gene: plod2 / 100036767
• ZFINID: ZDB-GENE-070326-1
• Length: 754
• Species: Danio rerio
• Alignment Length: 751
• Identity: 317/751 - (42%)
• Similarity: 477/751 - (63%)
• Gaps: 44/751 - (5%)

  Fly     8 LLLLLLAVTSQGDAESNWN---DKIKVFTVATEPTDGYTRYIRSARVYDIEVTTLGLGEEWKGGD 69
            :|:|:..|......|:|.:   :|:.|.||||:.|||:.|:::||..::..|..||:||||||||
Zfish    11 VLMLVTCVHCTLGMETNKDIPTEKLLVLTVATQETDGFLRFMQSANYFNFNVKVLGMGEEWKGGD 75

  Fly    70 M-QKPGGGFKLNLLREAIAPYKNEPETIILFTDSYDVIITTTLDEIFEKFKESGAKILFSAEKYC 133
            : ...|||.|:.||:||:.....:.:.::||.||||:|.....:||..||::|..|::|:||...
Zfish    76 VGHSIGGGQKVRLLKEAMESLDQQEDLVVLFVDSYDLIFAGGAEEILRKFQQSNHKVVFAAEGII 140

  Fly   134 WPDKSLANDYPEV-EGKASRFLNSGAFIGYAPQVFALLVD-PIEDTADDQLYFTKIFLDETKRAK 196
            |||..||..||.| .||  ||||||..|||||.:..|:.. .:.|..||||::|||::|..:|.|
Zfish   141 WPDSQLAEKYPSVRSGK--RFLNSGGIIGYAPYIQKLVSQWDLHDNDDDQLFYTKIYVDPIQREK 203

  Fly   197 LGLKLDVQSRLFQNLHGAKNDVKLKVDLESNQGVLQNVDFMTTPSIIHGNGLSKVDLNAYGNYLA 261
            |.:.||.:..:||||:||.::|.||...|..:  ::|..:.:.|::||||..:||..|...||:.
Zfish   204 LNMTLDHKCEIFQNLNGALDEVLLKFGTERVR--VRNTIYNSLPAVIHGNVNTKVYFNYLANYIP 266

  Fly   262 RTFN---GVCLLCQENLLDLEE-TNLPVISLALMVTQPVPFFDQFLEGIESLNYPKEKLHLLIYS 322
            ..:|   | |.:|.::::||.: ...|.:::.:.:.||.||..:|||.:.||:|||:||::.|::
Zfish   267 NAWNYERG-CTICDQDMVDLSQLKEFPQVTVGVYIEQPTPFLPEFLERLLSLDYPKDKLNIFIHN 330

  Fly   323 NVAFHDDDIKSFVNKHAKEYATAKFALSTDELDERQGRQLALDKARLHQS-DYIFFVDADAHIDD 386
            :..:|:..|:.|..::...:.:.|.....:.|.:.:.|.:.:|..|...| ||.|.:|||..:.:
Zfish   331 SEVYHEKHIQKFWEENKDVFGSFKAVGPEENLTQGEARNMGMDVCRRDPSCDYFFNIDADVMLTN 395

  Fly   387 GEVLRELLRLNKQFVAPIFSKHKELWSNFWGALSEGGYYARSHDYVDIVKRELIGMFNVPHVTSI 451
            .:.|:.|:..|::.:||:.::|.:||||||||||..||||||.||:|||:.:.:|::|:|.:..:
Zfish   396 RQTLKLLIEQNRKIIAPLVTRHGKLWSNFWGALSLDGYYARSEDYIDIVQGKRVGVWNIPFLAHV 460

  Fly   452 YLVK-KTAFDAIS----FKHKEFDPDMAMCESLRN---------------------AGIFMYASN 490
            ||:| :|..:.:.    |..::.|||||||.:.|:                     .|:|||.:|
Zfish   461 YLIKGQTLRNELKERNVFVLEKLDPDMAMCRNARDLTVHRERESPSPESFHMLRSPKGLFMYLTN 525

  Fly   491 LRIFGHLVNADDFNTTVTRPDFYTLFSNEIDWTEKYIHPNYSLQLNESNKIQQPCPDVYWFQIVS 555
            ...||.|::..::||:....|.:.:|.|.:||.|||||.||:....| |.::||||||:||.::|
Zfish   526 RHEFGRLISTANYNTSHYNNDLWQIFENPLDWREKYIHANYTRIFTE-NLLEQPCPDVFWFPVLS 589

  Fly   556 DAFCDDLVAIMEAHNGWSDGSNNDNRLEGGYEAVPTRDIHMKQVGLERLYLKFLQMFVRPLQERA 620
            :..|::||..||.|..||.|.:.|.|:.||||:|||.||||||:..::.:|.|::.|:.|:..:.
Zfish   590 EKACNELVEEMENHGTWSGGKHEDKRITGGYESVPTDDIHMKQINYDQEWLHFIREFISPVTLKV 654

  Fly   621 FTGYFHNPPRALMNFMVRYRPDEQPSLRPHHDSSTYTINIAMNRAGIDYQGGGCRFIRYNCSVTD 685
            |:||: ....|:|||:|:|.||.|..|||||||||:|||||:|..|:|:.||||||.|||||:..
Zfish   655 FSGYY-TKGYAIMNFVVKYTPDRQAYLRPHHDSSTFTINIALNNKGLDFLGGGCRFHRYNCSIES 718

  Fly   686 TKKGWMLMHPGRLTHYHEGLLVTNGTRYIMISFIDP 721
            .:|||..||||||||.||||.||||||||.:||:||
Zfish   719 PRKGWSFMHPGRLTHLHEGLPVTNGTRYIAVSFVDP 754

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Plod	NP_648451.1	GT_LH	27..257	CDD:459235	102/232 (44%)
		Glyco_tranf_GTA_type	303..>395	CDD:472172	27/92 (29%)
		P4Hc	555..719	CDD:214780	93/163 (57%)
plod2	NP_001082933.1	GT_LH	33..262	CDD:459235	102/232 (44%)
		BcsA	289..>404	CDD:440828	33/114 (29%)
		P4Hc	589..752	CDD:214780	93/163 (57%)