Protein Alignment GlcAT-P and B3GAT3

DIOPT Version :10

• Sequence 1: NP_648448.1
• Gene: GlcAT-P / 39262
• FlyBaseID: FBgn0036144
• Length: 479
• Species: Drosophila melanogaster
• Sequence 2: NP_036332.2
• Gene: B3GAT3 / 26229
• HGNCID: 923
• Length: 335
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 101/257 - (39%)
• Similarity: 142/257 - (55%)
• Gaps: 28/257 - (10%)

  Fly   221 RPTFVAASLP-----PPLYIITPTYRRPEQLAELTRLGYTLKHVVNLLWLVIEDANKTNPLVGHT 280
            ||....|..|     |.:|::||||.|..|.|||.||..||..|..|.||::|||....|||...
Human    60 RPPPAPAQPPEPEALPTIYVVTPTYARLVQKAELVRLSQTLSLVPRLHWLLVEDAEGPTPLVSGL 124

  Fly   281 LDRIGVPYEYMVAPMPEKYKQTKKAK-----PRGVSNRNRGLEYLREH-------------ATEG 327
            |...|:.:.::|...| |.::.::.:     ||||..||:.|::||..             .|:|
Human   125 LAASGLLFTHLVVLTP-KAQRLREGEPGWVHPRGVEQRNKALDWLRGRGGAVGGEKDPPPPGTQG 188

  Fly   328 VLYFADDDNTYDISIFEQMRYISKVAMWPVGLVTKTGVSSPIIQAGKLVGYYDGWIGGRKYPVDM 392
            |:|||||||||...:||:||:...|::||||||.......|.:|.|::||::..|...|.:||||
Human   189 VVYFADDDNTYSRELFEEMRWTRGVSVWPVGLVGGLRFEGPQVQDGRVVGFHTAWEPSRPFPVDM 253

  Fly   393 AGFAVSVKFLKERPNAQMPFKP--GYEEDGFLRSLAPLDDAEIELLADECRDILTWHTQTKK 452
            |||||::..|.::||||.....  |:.|...|..|  :|..::|..|..|..:|.|||:|:|
Human   254 AGFAVALPLLLDKPNAQFDSTAPRGHLESSLLSHL--VDPKDLEPRAANCTRVLVWHTRTEK 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GlcAT-P	NP_648448.1	GlcAT-I	231..452	CDD:132995	96/240 (40%)
B3GAT3	NP_036332.2	GlcAT-I	75..313	CDD:132995	96/240 (40%)
		Interaction with galactose moiety of substrate glycoprotein	243..252		3/8 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	312..335		1/2 (50%)